Surgical Department of Renhe Hospital of the Three Gorges University

Slides:



Advertisements
Similar presentations
CSF is produced - choroid plexus.
Advertisements

MOTOR NEURON DISEASE The motor neuron diseases (or motor neuron diseases) (MND) are a group of neurological disorders that selectively affect motor neurons.
Treatment of hydrocephalus at the Wessex Neurological Centre
CENTRAL NERVOUS SYSTEM PATHOLOGY
Dr. VASHDEV KHIMANI ASSISTANT PROFESSOR DEPT. OF NEUROSURGERY LUMHS JAMSHORO.
Online Module: Chiari Malformations. About the term To say “Chiari malformations” is slightly misleading. The Chiari malformations actually consist of.
Class grades 3 Quizzes Clinical Notebooks Due: 2 Exams
Congenital Malformations and Hydrocephalus
RCS 6080 Medical and Psychosocial Aspects of Rehabilitation Counseling Cerebral Palsy.
HYDROCEPHALUS.
Presaented by : Faisal Hussain . Majid Ahmed .
VIRAL ENCEPHALITIS A range of viruses can cause encephalitis but only a minority of patients have a history of recent viral infection. In Europe, the most.
Diseases of CNS By Dr. Abdelaty Shawky Dr. Gehan Abdel-Monem.
Assistant Professor Department of Paediatrics ANMC.
Care of Children Experiencing Alterations in Neurologic Function Marydelle Polk, Ph.D., ARNP-CS Florida Gulf Coast University.
1.  Hydrocephalus is the buildup in the cavities (ventricles) deep within the brain. The excess fluid increases the size of the ventricles and puts extra.
HYDROCEPH ALUS NEIL BARRY 11/0537/1159 MEDICAL AND SURGICALCONDITIONS.
Cerebrospinal fluid.
Online Module: Hydrocephalus
Differential Diagnosis of Hydrocephalus By: Nour-Eldin Mohammed Ref : Radiological Differential Diagnosis : Stephen Chapman,2003.
Hydrocephalus. Definition Hydrocephalus is the result of buildup of CSF in the ventricles of the brain Fig Hydrocephalus and Ventriculoperitoneal Shunts.
Dr Shreedhar Paudel May, 2009
Review Normal Pressure Hydrocephalus
Who Wants to be a Millionaire?. Question for $1,000,000 in Aug. 1998: The most common permanently disabling birth defect in the United States is: ● Down.
Online Module: Pseudotumor Cerebri
Barak Bar M.D. UCSF Department of Neurology
Pages Physical Protection:  Bone: Skull and vertebral column  Membranes: Skin/Scalp, Meninges  Watery Cushion: Cerebrospinal fluid (CSF) Chemical.
CEREBROSPINAL FLUID (CSF) AND THE BLOOD-BRAIN BARRIER (BBB)
WILL WESTON 4 TH Year Medical Student HYDROCEPHALUS IN CHILDHOOD.
INCREASED INTRACRANIAL PRESSURE Patrick C.J. Ward, M.D. Professor & Head Dept. of Anatomy, Microbiology & Pathology January, 2008.
SYB 2 Marni Scheiner MS IV Marni Scheiner MS IV. What kind of image is this, and what do you see?
Ventricles and Meninges
Show your best 3 Karl Clebak. Case Presentation  75 year old with rt shoulder numbness, lest sided trapezius muscle soreness fasciculation in left biceps.
Spina Bifida Lecture Format Introduction and Connecting Cause Symptoms Types Treatment Implications for Child, Family, Society.
Common Congenital Neurosurgical Diseases Dr. Abdulrazag Ajlan Modified from Dr. Essam Elgamal.
Ventricular System, Meninges, and CSF Study suggestion: Read the selected pages from Chapter 2 first, then read Chapter 8.
CSF and Ventricular System
Diseases/Disorders of the Nervous System. Categories of Conditions Trauma Structural abnormalities Degenerative Infectious Mental Health.
Congenital malformations and hydrocephalus
Morning Report Acute Ataxia 8/31/09 Lorena Muñiz, MD.
Congenital CNS abnormality إعــــداد م. د. علي طارق عبد الواحد إختصاص جراحة الجملة العصبية كلية الطب / جامعة بغداد 2015.
Diagnosis and Treatment of Idiopathic Normal Pressure Hydrocephalus
Intracerebral Hemorrhage
The Nervous System Responsible for Sending, Receiving, and Processing nerve impulses. Includes 3 sub-systems working together: Central – analyze data,
Diseases of Nervous System Fatima Obeidat, MD Pathologist/Neuropathologist The University of Jordan Lecture 2.
 Common neurosurgical conditions seen in primary care Brian Jochim MSN, APRN, FNP.
Normal Pressure Hydrocephalus
HYDROCEPHALUS. Definition: Hydrocephalus is defined as abnormal accumulation of cerebrospinal fluid (CSF) within the ventricles and subarachnoid spaces.
Do Now 2/9/15 1.Describe possible causes for forgetting a memory. 2.Compare and contrast semantic and episodic memories.
 The term hydrocephalus is derived from the Greek words “hydro” meaning water and “cephalus” meaning head. As the name implies, it is a condition in.
The Nervous System Medical Terminology Unit 10. CNS – Central Nervous System.
The under drainage problems of Low-Pressure Hydrocephalus Patients: A clinical study Vaner Köksal /Recep Tayyip Erdoğan University Introduction; font size.
Case presentation in normal pressure hydrocephalus 中國醫藥大學附設醫院神經部 楊玉婉.
The brain of the blue baby… NEUROLOGY MODULE Pediatrics II.
Hydrocephalus. Hydrocephalus also known as "water on the brain", is a medical condition in which there is an abnormal accumulation of cerebrospinal fluid.
Cerebrospinal fluid. The subarachnoid space on the outside of the brain is in continuity with a similar space around the spinal cord and also with the.
Sponge: Set up Cornell Notes on pg. 19 Topic: 11.2: Ventricles- CSF and TBI Essential Question: None. 2.1 Atoms, Ions, and Molecules 11.2:Ventricles-CSF-
Disorders of the Central Nervous System, Drugs and Alcohol
Nervous System Disorders and Homeostatic Imbalances
HYDROCEPHALUS.
Cerebral Oedema Classification: Vasogenic Oedema Cytotoxic Oedema
Hydrocephalus.
Hydrocephalus.
Increased Intracranial Pressure
Get out work from yesterday
Hydrocephalus Disease
HYDROCEPHALUS.
Cerebrospinal fluid.
Presentation transcript:

Surgical Department of Renhe Hospital of the Three Gorges University Hydrocephalus By M.D. Wenbing Ai Surgical Department of Renhe Hospital of the Three Gorges University

What is Hydrocephalus? The term hydrocephalus is derived from the Greek words “hydro” meaning water and “cephalus” meaning head. As the name implies, it is a condition in which the primary characteristic is excessive accumulation of fluid in the brain. The excessive accumulation of cerebrospinal fluid (CSF) results in an abnormal dilatation of the spaces in the brain called ventricles. This dilatation causes potentially harmful pressure on the tissue of the brain.

What is Hydrocephalus? Also can be defined: diverse group of conditions which result from impaired circulation and resorption CSF.

Hydrocephalus

Hydrocephalus

Pathologic specimen of brain Lateral ventricle Third ventricle Fourth ventricle

Enlarged Ventricles

Enlarged Ventricles

CSF Formation CSF is formed by the choroid plexus . Normal CSF production: 20 ml/h.

CSF functions CSF performs the following functions: Balances the amount of blood in the head. Bathes and protects the brain and spinal cord. Carries nutrients between the brain and spinal cord while removing waste.

CSF pathway Flows from lateral ventricles through foramina of Monro into third ventricle Enters fourth ventricle through aqueduct of Sylvius Enters subarachnoid space Resorbed by arachnoid villi at top of brain

CSF homeostasis (summary) Production: floor of the lateral ventricle and third ventricle, by choroid plexus Circulation: L.V. -> III.V. -> IV.V. -> exits ventricular system into various basal cisterns and then to subarachroid space Drains back to blood via arachnoid granulation to superior sagittal sinus, or via spinal nerve roots, or via olfactory tracts Imbalance causes pathology From Johanson CE

A flash of CSF circulation

Mechanism of hydrocephalus formation CSF * Obstruction of CSF pathway * functional disturbance of CSF absorption * Excessive production of CSF Excessive accumulation Cerebral ventricles or subarachnoid space enlargement Head enlargement Increasing ICP Cerebral dysfunction

A flash of CSF circulation

Types of hydrocephalus According to different standards: Noncommunicating (obstructive) hydrocephalus and communicating hydrocephalus Congenital hydrocephalus(developed before birth) and acquired hydrocephalus(developed during or after birth) Normal pressure hydrocephalus (NPH) and increasing pressure hydrocephalus Acute hydrocephalus and chronic hydrocephalus

Types of hydrocephalus Communicating hydrocephalus:the obstruction occurs in the subarachnoid space. Noncommunicating hydrocephalus: the obstruction is located within the ventricles.

Types of hydrocephalus Obstructive hydrocephalus Congenital malformations After inflammation or hemorrhage Mass lesions Communicating hydrocephalus Overproduction of CSF Defective absorption of CSF Venous drainage insufficienc

Causes of hydrocephalus Congenital causes in infants and children Stenoses of the aqueduct of Sylvius due to malformation: 10% of all cases of hydrocephalus in newborns. Dandy-Walker malformation: 2-4% of newborns with hydrocephalus. Arnold-Chiari malformation type 1 and type 2 Agenesis of the foramen of Monro Congenital toxoplasmosis Bickers-Adams syndrome: an X-linked hydrocephalus accounting for 7% of cases in males. It is characterized by stenosis of the aqueduct of Sylvius, severe mental retardation, and in 50% by an adduction-flexion deformity of the thumb.

Causes of hydrocephalus Acquired causes in infants and children Mass lesions account for 20% of all cases of hydrocephalus in children. Intraventricular hemorrhage Infections: Meningitis (especially bacterial) and cysticercosis Increased venous sinus pressure: related to achondroplasia, some craniostenoses, or venous thrombosis. Iatrogenic: Hypervitaminosis A, by increasing secretion of CSF or by increasing permeability of the blood-brain barrier Idiopathic

Causes of hydrocephalus Causes of hydrocephalus in adults Subarachnoid hemorrhage (SAH) causes one third of these cases by blocking the arachnoid villi. Idiopathic hydrocephalus represents one third of cases of adult hydrocephalus. Head injury, through the same mechanism as SAH, can result in hydrocephalus. Tumors can cause blockage anywhere along the CSF pathways. Posterior fossa surgery Congenital aqueductal stenosis causes hydrocephalus but may not be symptomatic until adulthood. Meningitis, especially bacterial, may cause hydrocephalus in adults. All causes of hydrocephalus described in infants and children are present in adults who have had congenital or childhood-acquired hydrocephalus.

Causes of hydrocephalus Causes of NPH SAH Head trauma Meningitis Tumors Posterior fossa surgery Idiopathic, probably related to a deficiency of arachnoid granulations

Clinical features Clinical features of hydrocephalus are influenced by the following: Patient's age Cause Location of obstruction Duration Rapidity of onset

Clinical features Symptoms in infants Poor feeding Irritability Reduced activity Vomiting

Clinical features Symptoms in children Slowing of mental capacity Headaches (initially in the morning) that are more significant than in infants because of skull rigidity Neck pain suggesting tonsillar herniation Vomiting, more significant in the morning Blurred vision - Consequence of papilledema and later of optic atrophy Double vision - Related to unilateral or bilateral sixth nerve palsy Stunted growth and sexual maturation from third ventricle dilatation: Difficulty in walking secondary to spasticity Drowsiness

Clinical features Symptoms in adults Cognitive deterioration. Headaches: These are more prominent in the morning. As the condition progresses, headaches become severe and continuous. Neck pain: If present, indicate herniation of cerebellar tonsil . Nausea. Vomiting: Sometimes explosive, more significant in the morning. Blurred vision. Double vision from sixth nerve palsy Difficulty in walking Drowsiness Incontinence: This indicates significant destruction of frontal lobes and advanced disease.

Clinical features Symptoms of NPH Gait disturbance is usually the first symptom and may precede other symptoms by months or years. Dementia presents as an impairment of recent memory or as a "slowing of thinking." The degree can vary from patient to patient. Urinary incontinence presents as a lack of or diminished awareness of the need to urinate. Some patients may have urgency. Other symptoms that can occur include aggressive behavior, Parkinsonlike symptoms, and seizures.

Clinical features Sign in infants Head enlargement. Dysjunction of sutures. Dilated scalp veins. Tense fontanelle: The anterior fontanelle in infants may be excessively tense. Setting-sun sign: Increased limb tone.

Clinical features Sign of children Papilledema. Failure of upward gaze. Macewen sign: A "cracked pot" sound is noted on percussion of the head. Unsteady gait. Large head. Unilateral or bilateral sixth nerve palsy.

Clinical features Sign of adults Papilledema: If raised ICP is not treated, it will lead to optic atrophy. Failure of upward gaze and of accommodation indicates pressure on the tectal plate. Unsteady gait is related to truncal and limb ataxia. Spasticity in legs also causes gait difficulty. Large head: The head may have been large since childhood. Unilateral or bilateral sixth nerve palsy is secondary to increased ICP.

Clinical features Sign of NPH Muscle strength is usually normal. No sensory loss is noted. Reflexes may be increased, and Babinski response may be found in 1 or both feet. Difficulty in walking varies from mild imbalance to inability to walk or to stand. Gait is characterized by short steps, inability to raise legs, and almost continuous activity in antigravity muscles. The patient cannot perform tandem walking and sways during Romberg test with eyes open or closed. Sucking and grasping reflexes appear in late stages.

Diagnosis How to diagnose hydrocephalus: Cases history. Symptoms and signs mentioned above. diagnostic imaging like Skull X-rays, echoencephalogram ultrasound, CT, and MRI. Lumbar punctures ultrasound CT MRI

Normal brain MRI imaging T1WI T1WI T1WI T2WI T2WI T2WI

Normal brain CT axial view

Normal Ventricles

Enlarged Ventricles

Communicating hydrocephalus

Communicating hydrocephalus

Obstructive hydrocephalus

Obstructive hydrocephalus

Obstructive hydrocephalus

Stenoses of the aqueduct of Sylvius due to malformation

Congenital malformation with hydrocephalus

Hydrocephalus caused by brain hemorrhage

Hydrocephalus after head injury

Hydrocephalus after SAH

Treatment of hydrocephalus The main goal is to minimize or prevent brain damage by improving CSF flow. Main therapy: Medical treatment:To decrease the ICP or reduce the production of CSF with drugs. Surgical interventions.

Surgical interventions Treating the causes:searching for and direct removal of the obstruction is the best strategy. Shunt procedure:the main ways are V-P shunt and V-A shunt, the most common is V-P shunt. Third Ventriculostomy

Shunt procedure A surgical shunt within the brain may allow CSF to bypass the obstructed area, if obstruction cannot be removed.

Shunt procedure Ventriculo-Peritoneal Shunt (V-P Shunt) Ventriculo-Atrial shunt (V-A Shunt)

Before and After

Third Ventriculostomy Third Ventriculostomy allows movement of CSF from a blocked ventricle to the aubarachnoid space. The procedure involves making tiny holes in the floor of the third ventricle allowing CSF to flow into the subarachnoid space. Third Ventriculostomy can eliminate the need for a shunt in some cases, though the procedure is not the apropriate solution in all cases.

Third Ventriculostomy

Third Ventriculostomy Post-operation Pre-operation

Thank you!