Bell Ringer Why is it important for people in a hospital to get the right blood type when they need if for a transfusion?
History 1901 Austrian Karl Landsteiner discovered human blood groups blood transfusions became safer Awarded Noble Prize in 1930.
Blood Type Determined by proteins called antigens on the surface of your blood. With different antibodies Ex: Type A blood has A antigens but B antibodies. A antibodies would attack A blood.
Human Blood Types
Phenotype (Blood Type) Genotype Antigen on Red Blood Cell Safe Transfusions To From ABO Group
O – universal donor No antigens AB – universal recipient No antibodies Important in blood transfusions and paternity suits
ABO Blood Group Single gene I - has 3 different alleles Multiple Alleles Blood type A genotype I A I A I A i Blood type B genotype I B I B I B i Blood type ABgenotype I A I B (codominant) Blood type O genotype ii (recessive)
Rh Group Determined by single gene with 2 alleles Rh positive (Rh + /Rh + or Rh + / Rh - ) Rh negative (Rh - /Rh - ) Rh + can never be given to Rh - people Can cause a mother’s body to attack a fetus.