FUTURE RESEARCH ON MALARIA: Towards a malaria-free country Emiliana Tjitra National Institute of Health Research and Development Jakarta, 30 April 2015.

Slides:

Advertisements

Similar presentations

New Challenges in M&E Lets go. Scaling Up Monitoring & Evaluation Strategic Information PROGRAM GUIDANCE RESULT NEEDS OPPORTUNITIES Resources New directions.

Advertisements

Strategic Information for Anti-RetroViral Treatment Programmes Workshop WHO and UNAIDS Geneva June 30- July Ties Boerma HIV Department Surveillance,

TB/HIV Research Priorities: TB Preventive Therapy.

Track C on prevention issues Recognised Priority technical areas are ITNs, malaria in pregnancy, vector control, including use of DDT epidemics and complex.

Anti-Malaria Chemotherapy

National Strategic Plan for Elimination of Malaria in Cambodia ( )

Malaria Elimination in Zanzibar. Introduction Dramatic declines in malaria morbidity and mortality over the last decade (prevalence remained

Caroline Lynch & Jim Tulloch June 2014 Synthesis of current evidence on the multiple causes of malaria drug resistance.

Challenges & responses for malaria in Asia

Introduction Epidemiology and global situation Policies and targets for malaria control Strategies for control Antimalarial drugs Vector control Progress.

Global Hepatitis C Guidelines 2014: recommendations for a public health approach Gottfried Hirnschall.

Regional initiative to sustain country achievement SEAR Krongthong Thimasarn Regional Adviser, Malaria World Health Organization Regional Office for South-

The Work of WHO in the South-East Asia Region The Work of WHO in the South-East Asia Region Biennial Report of the Regional Director 1 January

World Health Organization

1 Global Malaria Programme Update from the Global Malaria Programme Update from the Global Malaria Programme Silvia Schwarte Diagnosis, Treatment and Vaccines.

1 Global and Regional Tuberculosis (TB) update ACSM workshop, Amman, Jordan April 13-17, 2008 Dr. Sevil Huseynova.

Anti-Malaria Drug Policy Philippines

Malaria Situation & Drug Policy Malaysia Infectious Disease Consultant/Physician MOH Malaysia.

Impact evaluation Evaluate new tools Translate new knowledge into policy and implementation Knowledge gap Program implementation.

Overview of Guyana’s Malaria Situation Dr. Reyaud Rahman.

The Research and Development Goals of the Global Plan to Stop TB Marcos Espinal Executive Secretary.

Ecdc.europa.eu Tommi Asikainen, Tubingen, 22 October 2008 European Centre for Disease Prevention and Control FUTURE DISEASE CHALLENGES IN EUROPE – where.

African Business Leaders on Health: GBC Conference on TB, HIV-TB Co-infection & Global Fund Partnership Johannesburg, October 11, 2010 The state of Global.

Malaria Case management KPA conference. Presentation outline  Introduction  National malaria strategy  Case management targets  AMFm subsidy  The.

Malaria treatment policies: the challenge, strategies and the options SOTA, Nairobi, Kenya 12 th June 2002.

Containment of artemisinin resistance at the Cambodia-Thailand border Sylvia Meek, Technical Director, Malaria Consortium, CMWG Meeting 8 July 2009.

Health Organization The Challenges Facing Tuberculosis Control Blantyre Hospital, Malawi: TB Division, 3 patients per bed.

Issues in malaria diagnosis and treatment May 31, 2007 Jacek Skarbinski, MD Malaria Branch Centers for Disease Control and Prevention.

The Multi-Sectoral Provincial Strategic Plan for HIV & AIDS, STIs & TB of KwaZulu-Natal Presentation to PEPFAR all partners meeting Monday 28.

Group B Comparison of the different types of programs.

Indicators in Malaria Program Phases By Bayo S Fatunmbi [Technical Officer, Monitoring & Evaluation] ERAR-GMS, WHO Cambodia & Dr. Michael Lynch Epidemiologist.

Indicators in Malaria Program Phases By Bayo S Fatunmbi [Technical Officer, Monitoring & Evaluation] ERAR-GMS, WHO Cambodia.

Overall Malaria Situation and Challenges in Lao PDR 7 July 2015 Updating of Malaria NSP Stakeholder Workshop Thalat, Vientiane Province Dr. Bouasy Director,

Zambia Active Parasite Detection (APD) 2011 Questionnaire.

An update of artemisinin resistance and its containment efforts

Case definitions & classification. Malaria case (as defined in elimination programmes) A case in which, regardless of the presence or absence of clinical.

Group1 Vector Control Challenges and OR needs. Challenges: Brainstorming challenges and categorized into 3 groups: 1.Strategic Information – Vector and.

SOP for malaria case surveillance

CASE DETECTION by Dr Mikhail Ejov WHO Training in Malaria Elimination in the Greater Mekong Sub-Region, August 2015, Chiang Mai Thailand 1.

Epidemiology. Epidemiology involves: –determining etiology of infectious disease –reservoirs of disease –disease transmission –identifying patterns associated.

Relative cost of antimalrial drug

+ Quality Assessment of Malaria Diagnosis on the Thai-Burma Border Jaime Moo-Young Noon Conference, Harborview Medical Center June 1, 2010.

STRATEGIC INFORMATION FOR ACTION IN VIET NAM 6 th Viet Nam National Scientific Conference 24 November 2015 Ha Noi, Viet Nam Amitabh Bipin SUTHAR, PharmD,

Summary of potential priority actions for CMWG Case Management Working Group Meeting 8-9 July 2009.

Unit 4 Approaches and Interventions in Pre- Elimination, Elimination and Prevention of Reintroduction Case Management, G6PD, etc and selections of interventions.

Group 2 – D3. Question 1.Is the RDT suitable for use in elimination phase? RDT for both P.f, P.v species RDT use in village level, in hard risk areas.

Malaria a story of ELIMINATION A partnership of:.

Global Health Malaria. Transmission Malaria is spread by mosquitoes carrying parasites of the Plasmodium type. Four species of Plasmodium are responsible.

TB in Yorkshire and the Humber Dr Simon Padfield 14 th Sept 2007.

Tuberculosis - the opportunity in our lifetime Dr. Lucica Ditiu | Executive Secretary | Stop TB Partnership 09.April.2013 | Brussels, Belgium.

2007 Pan American Health Organization 2004 Pan American Health Organization Malaria in the Americas: Progress, Challenges, Strategies and Main Activities.

Sayed Ali Mus POST GRADUATES-BATCH 6 FACULTY OF MEDICAL LABORATORY SCIENCES PARASITOLOGY DEPARTMENT ALNEELIN UNIVERSITY March 2015 Symposium on: Advances.

TB AND HIV: “THE STRATEGIC VISION FOR THE COUNTRY” Dr Lindiwe Mvusi 18 May 2012 MMPA Congress 2012.

Malaria Elimination in South East Asia Region Progress, Challenges and the Way Forward Dr. Deyer Gopinath, WHO / Thailand Dr. Leonard Ortega, WHO / SEARO.

World Health Organization

Seasonal Malaria Chemoprevention: WHO Policy and Perspectives

Malaria Elimination Programme Timor Leste

Human Resource Requirements for Malaria Elimination

Malaria in Tribal Areas

FP6 Priority 1, Life Sciences Genomics and Biotechnology for Health

William Burman Denver Public Health Tuberculosis Trials Consortium

Progress: Bangladesh CCM GF SEA Constituency Meeting New Delhi, India

Monitoring the implementation of the TB Action Plan for the WHO European Region, 2016–2020 EU/EEA situation in 2016 ECDC Tuberculosis Programme European.

Call topic identification for 2019 call

"Overview of Malaria incidence (API) and control in Solomon Islands"

FP6 Priority 1, Life Sciences Genomics and Biotechnology for Health

Hannah C. Slater, Lucy C. Okell, Azra C. Ghani Trends in Parasitology

The STOP TB Strategy – 2009 VISION: A TB-free world

Novel Population-Level Malaria Treatment Strategies for the 2020s

Rapid Detection of HIV-1 subtype C Integrase resistance mutations by the Use of High-Resolution Melting Analysis Tendai Washaya BSc, Msc. Pre-PhD Student.

Presentation transcript:

FUTURE RESEARCH ON MALARIA: Towards a malaria-free country Emiliana Tjitra National Institute of Health Research and Development Jakarta, 30 April 2015

OUTLINE NIHRD output indicators NMCP output indicators Malaria Elimination Areas Problems, Challenges and Future Research Summary

NIHRD Output Indicators Recommendation to improve National Malaria Control Program Novelty: Patent, Copy Right etc Publication

NMCP Output Indicators districts are in eliminated malaria stage districts are in eliminated malaria stage districts are in eliminated malaria stage 285 districts are in eliminated malaria stage districts are in eliminated malaria stage Note: 2014: 213

Malaria Elimination Areas in Indonesia Legend Control areas Pre elimination areas Elimination areas Subdit Malaria, 2012

Future Research Challenges Problems

- Marker for imported cases - Prevalence of G-6 PD deficiency - Marker for Pv relapse and resistance - Mode of Pk transmission - Marker for artemisinin resistance - Polymorphism of Pf, Pv and others - Diagnosis of dormant Pv or Po and Pk - Distinguishing of Pv relapse and resistance - Monitoring therapeutic efficacy /drug resistance Towards malaria elimination - Imported/non-indigenous cases - Zoonotic P.kowlesi - Spreading of artemisinin resistance Epidemiology/Surveillance

- Validated and highly sensitive RDT - Marker for Pv/Po liver stage /hypnozoite/dormant stage - Marker for Pk - Tools for field G-6PD deficiency test - Sensitivity of RDT for Pv and other non Pf - Diagnosis of Pk - Field G-6PD test -Microscopist skill -RDT for Pf and non Pf (Pv, Pm dan Po) - None for P.kowlesi - G-6PD deficiency Diagnosis

-Ideal ACT/other antimalarial drugs -Field drug level/concentration measurement technique -Pharmacogenome of artemisinin derivatives resistance - Genotype artemisinin resistance - - Simple and practical alternative ACT - Baseline PK and PD of ACT program in Pf. Pv patients and population - Other radical treatment regimen -Endemic malaria country and mostly in remote areas -All human Plasmodia and zoonotic malaria -Affects all age groups -Compliance -Only DP as ACT program -Decreased ACT efficacy in neighboring countries -Accelerated malaria elimination Treatment

-Effective polyvalent vaccine -Vaccine trial - Vaccine development to prevent infection and relapse/ disease/transmission -Migration and mobile population -All human Plasmodia and Pk -Lots of potential vectors -Health policy priority: promotion and prevention approach Vaccine

Polyvalent vaccine to prevent infection Rapid and highly sensitive diagnostics to detect plasmodia Ideal antimalarial drug for radical treatment Summary Field surveillance tools for low incidence and prevalence

Thank You