Morinda citrifolia (Noni). Major Component  Vitamin C, carotene, vitamin A  Potassium  Sterol  flavanoid.

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Presentation transcript:

Morinda citrifolia (Noni)

Major Component  Vitamin C, carotene, vitamin A  Potassium  Sterol  flavanoid

Biological activity  Antimicrobial Antibacterial: fruit, root Antiviral: root Anti TB: leaves Anti helmintic: ascaris: leaves  Antitumor activity: fruit juice Animal cancer Leukemia cell line

 Analgesic activity: animal  Antiinflammatory: in vitro cox-2 inhibitor  Hypotensive activity: root  Immunological: fruit Inhibit TNF-, stimulate IF, IL2  antioxidant activity Biological activity

Clinical Survey  67% of cancer(847) significant lessening symptoms  72% of overwt lose wt  87% of hypertensive has drop in BP  90% of chronic pain improve pain  80% arthritis improve symptom

Conclusion  Animal model or in vitro study  In human study: descriptive, subjective, byass

The effects of green tea consumption on incidence of breast cancer and recurrent of breast cancer: a systematic review and meta-analysis  Aim: determine the efficacy of green tea on risk of BC development and BC recurrent  SR and meta-analysis of observational studies 8 Integ Cancer Ther 2005, 4:

 Pool relative risk of developing BC in highest consumption 0.89 [ ], p =0.28  In case control: OR 0.44 [ ]. P=0.14  Subgroup analysis of recurrent in stge I, II pool RR 0.56[ ] p=0.004  Dose response relationship The effects of green tea consumption on incidence of breast cancer and recurrent of breast cancer: a systematic review and meta-analysis Integ Cancer Ther 2005, 4:

 Consumption of > 5 cups of green tea/d shows non statistical sig trend towards prevention of BC  Green tea consumption may possibly help prevent breast cancer recurrence in stage I, II The effects of green tea consumption on incidence of breast cancer and recurrent of breast cancer: a systematic review and meta-analysis Integ Cancer Ther 2005, 4:

Conclusion of potential therapeutic application are currently impossible  Small number of studies  lack of clinical trial evidence  Lack of consistent dose-response relationship  Potential for interaction with standard care

Fatty Acid Content in Edible Oil % of total fat