Unique Selling Points (USP) ROXY and Accessories Antec BV Zoeterwoude, The Netherlands 1

Product Overview Accessories - ReactorCell™ - µ-PrepCell™ ROXY™ Potentiostat ROXY™ EC System ROXY™ EC/LC System

USP ReactorCell™ thin-layer ReactorCell™ working electrodes & holder Dedicated analytical cell, low volume 0.7ul Easy and quick exchange of working electrode Zero sample adsorption compared to porous flow through cell (carry over) due to thin-layer flow cell Standard supplied with 4 working electrodes, i.e., Pt, Au, GC, MD

USP µ-PrepCell™ thin-layer µ-PrepCell™ with mounting brace Patent pending Excellent conversion rate (µg quantities of metabolites in a few minutes) Zero sample adsorption with proprietary thin-layer cell, unlike cells with porous electrodes Fast and easy working electrode exchange Generation of intermediate reaction products (amperometric mode)

USP ROXY™ Potentiostat Voltage range, +/- 4.9 Volt for wide range scanning Multiple cell control, standard 2, optional up to 4 Scan mode: for rapid measurement of optimal Redox potential Activation mode: for optimal working electrode conditioning Upgradable to ROXY (LC)/EC system ROXY™ Potentiostat with 2 ReactorCells™

USP ROXY™ EC System ROXY™ EC System Direct on-line EC/MS, no need for LC Fast metabolite profiling, phase I and II metabolism Dedicated Dialogue™ software - for automated voltage scanning and - control of syringe pump and ROXY Huge time and cost savings compared to in vivo or in vitro techniques MS Voltamogramm

USP ROXY™ EC/LC System Automated screening of numerous drug compounds/ xenobiotics on metabolism Electrochemical cell integrated in autosampler 1), for non-compromised EC, LC and MS On-line EC/LC/MS of complex samples Compatibility with any MS 1) Intl. Patent Application PCT/NL2010/ ROXY™ EC/LC System

Last but not least… ROXY™ has been awarded with the prestigious GIT Publisher award (a Wiley Company) as the most innovative product introduced at Analytica 2010, Munich, Germany. Gold Star for ROXY’s 1 st place!