Survival, response duration, and activity by BRAF mutation (MT) status of nivolumab (NIVO, anti-PD-1, BMS-936558, ONO-4538) and ipilimumab (IPI) concurrent.

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Presentation transcript:

Survival, response duration, and activity by BRAF mutation (MT) status of nivolumab (NIVO, anti-PD-1, BMS , ONO-4538) and ipilimumab (IPI) concurrent therapy in advanced melanoma (MEL) Presented By Mario Sznol at 2014 ASCO Annual Meeting

Disclosures Presented By Mario Sznol at 2014 ASCO Annual Meeting

Ipilimumab and Nivolumab Clinical Experience in Patients with Advanced Melanoma Presented By Mario Sznol at 2014 ASCO Annual Meeting

Objectives Presented By Mario Sznol at 2014 ASCO Annual Meeting

CA Phase I Study: Dose Cohorts Presented By Mario Sznol at 2014 ASCO Annual Meeting

Patient Demographics Presented By Mario Sznol at 2014 ASCO Annual Meeting

Activity Summary: Concurrent and Sequenced Cohorts from 004 Presented By Mario Sznol at 2014 ASCO Annual Meeting

Response in Target Lesions Presented By Mario Sznol at 2014 ASCO Annual Meeting

Slide 9 Presented By Mario Sznol at 2014 ASCO Annual Meeting

Characteristics of Response Presented By Mario Sznol at 2014 ASCO Annual Meeting

Safety Overview Presented By Mario Sznol at 2014 ASCO Annual Meeting

ORR by BRAF Status for Concurrent Cohorts Presented By Mario Sznol at 2014 ASCO Annual Meeting

ORR by PD-L1 Status (5% cutoff) Presented By Mario Sznol at 2014 ASCO Annual Meeting

ORR by Ipilimumab Exposure at Time of Nivolumab Treatment Presented By Mario Sznol at 2014 ASCO Annual Meeting

Overall Survival for Concurrent Therapy by Dose Cohort Presented By Mario Sznol at 2014 ASCO Annual Meeting

Survival Endpoints for Concurrent and Sequential Therapy by Dose Cohort Presented By Mario Sznol at 2014 ASCO Annual Meeting

Conclusions Presented By Mario Sznol at 2014 ASCO Annual Meeting

Acknowledgments Presented By Mario Sznol at 2014 ASCO Annual Meeting