Blood

The different components of blood

RBC’s/Erythrocytes Transports O2 (on hemoglobin) Transports CO2 (on hemoglobin)

LEUKOCYTE FUNCTION: SEE TALBE 21.3—GREAT FUNCTION SUMMARY

Leukocytes Functions

Lymphocyte Basophil Neutrophil eosinophil Monocyte Leukocytes—WBC’s Granulocytes: have granules in cytoplasm Agranulocytes: no granules in cytoplasm

Neutrophils Function Phagocytize pathogens –particularly bacteria Structure/ID Multilobed (3-5) nucleus Inconspicuous granules ~2x size of rbc

Eosinophil Function Kills/attacks parasites Phagocytize allergens and antigen antibody complexes –reduces inflammation and allergic rxns Structure/ID ~ 2x size of rbc Very conspicuous red granules Bilobed nucleus

Basophil Function produces histamine and heparin –Promote inflamation: Structure/ID ~2x size of rbc Bilobed nuclues Very conspicuous blue granules

Monocytes Function Leaves vessels and then phagocytizes microorganisms and debri Structure/ID ~ 3x size of RBC/largest WBC Lobed  kidney shaped nucleus No granules

lymphocyte Function Produces antibodies (specific immunity) Structure/ID Slightly larger then rbc Round Nucleus fills most of cell No granules

Comparing Leukocytes A D CB

Platelets Function Reduce blood loss Platelet plug/clotting Stucture/ID Cell fragments Small (much smaller then rbc), darkish

Relative Abundance of Leukocyes Never Let Monkeys Eat Bananas »Nuetrophils (most common wbc) »Lymphocytes »Monocytes »Eosinophils »Basophils (least common wbc)

Differential WBC count Because: there is a typical amount of each WBC Each WBC has a different function WBC respond to their specific challenges by increasing in number Counting the relative abundance of each WBC (differential WBC count) can help assess what a condition/problem is

Normal WBC Frequencies Blood CellNormal Value Neutophil52-62% Eosinophil1-3% BasophilLess then 1% Lymphocyte25-33% Monocyte3-9%