ERYTHEMA NODOSUM DEFINITION-THIS IS A REACTVE DERMATOSIS THAT OCCERS IN RESPONSE TO A MYRIAD OF CONDITION CHARACTERISED BY TENDER, ERYTHEMATOOUS DEFINITION-THIS IS A REACTVE DERMATOSIS THAT OCCERS IN RESPONSE TO A MYRIAD OF CONDITION CHARACTERISED BY TENDER, ERYTHEMATOOUS SUB CUTANEOUS NODULES PRIMARILY AFFECTING THE LOWER EXTREMITIES SUB CUTANEOUS NODULES PRIMARILY AFFECTING THE LOWER EXTREMITIES MOST COMMEN TYPE OF PANNICULITIS MOST COMMEN TYPE OF PANNICULITIS AGE 20 TO 30 YEARS BUT ANY AGE GROUP MAY BE AFFECTED AGE 20 TO 30 YEARS BUT ANY AGE GROUP MAY BE AFFECTED FEMALE:MALE 3-6 :1 FEMALE:MALE 3-6 :1

ETIOLOGICAL AGENTS BACTERIAL- BACTERIAL- STREPTOCOCCAL INFECTION, TUBERCULOSIS,YERSINIOSIS,BRUCELLOSIS,SALMONELL A STREPTOCOCCAL INFECTION, TUBERCULOSIS,YERSINIOSIS,BRUCELLOSIS,SALMONELL A FUNGAL INFECTION – COCCIDIOIDOMYCOSIS,BLASTOMYCOSIS,HISTOPLASMO SIS, DERMATOPHTOSIS FUNGAL INFECTION – COCCIDIOIDOMYCOSIS,BLASTOMYCOSIS,HISTOPLASMO SIS, DERMATOPHTOSIS VIRAL INFECTION– INFECTIOUS MONONUCLEOSIS, ORF, HEPATITIS-B HERPES SIMPLEX VIRAL INFECTION– INFECTIOUS MONONUCLEOSIS, ORF, HEPATITIS-B HERPES SIMPLEX PARASITIC INFESTATION - AMEBIASIS, GIARDIASIS, PARASITIC INFESTATION - AMEBIASIS, GIARDIASIS, DRUGS – SULFONAMIDES,BROMIDES,IODIDES,ORAL CONTRACEPTIVE, MINOCYCLINE,SALISYLATES DRUGS – SULFONAMIDES,BROMIDES,IODIDES,ORAL CONTRACEPTIVE, MINOCYCLINE,SALISYLATES MALIGNANCIES – HODGKIN’S, NON HODGKIN;S LYMPHOMAS MALIGNANCIES – HODGKIN’S, NON HODGKIN;S LYMPHOMAS SARCOIDOSIS SARCOIDOSIS INFLAMMATORY BOWEL DISEASE,ULCERATIVE COLITIS,CRON’S DISEASE,BECET’S DISEASE INFLAMMATORY BOWEL DISEASE,ULCERATIVE COLITIS,CRON’S DISEASE,BECET’S DISEASE

CLINICAL PRESENTATON SUDDEN ONSET SUDDEN ONSET SYMMETRICAL SYMMETRICAL PAINFUL PAINFUL ERYTHEMATOUS ERYTHEMATOUS WARM WARM NONULCERATED NODULES/PLAQUES NONULCERATED NODULES/PLAQUES KNEES, SHINS,FEET KNEES, SHINS,FEET MAY BE AT THIGHS,ARMS, & FACE MAY BE AT THIGHS,ARMS, & FACE UNDERGO COLOUR CHANGES AS ADVANCE IN THE DURATION UNDERGO COLOUR CHANGES AS ADVANCE IN THE DURATION RESOLVE WITHOUT SCARRING OR ATROPHY RESOLVE WITHOUT SCARRING OR ATROPHY ASSOCIATED WITH PYREXIA,MALAISE, HEADACHE ARTHRALGIAS ASSOCIATED WITH PYREXIA,MALAISE, HEADACHE ARTHRALGIAS RECURRENT EPISODES ARE KNOWN RECURRENT EPISODES ARE KNOWN

ERYTHEMA NODOSUM

HISTOPATHOLOGY SEPTAL PANICULITIS WITHOUT VASCULITIS SEPTAL PANICULITIS WITHOUT VASCULITIS

TREATMENT TREATMENT OF UNDERLYING DISEASE TREATMENT OF UNDERLYING DISEASE SPONTANEOUSLY RESOLVES SPONTANEOUSLY RESOLVES NONSTEROIDAL ANTI-INFLAMMATORY AGENTS- ASPIRIN, INDOMETHACINE,NAPROXEN NONSTEROIDAL ANTI-INFLAMMATORY AGENTS- ASPIRIN, INDOMETHACINE,NAPROXEN ORAL POTASSIUM IODIDE 400 TO 800 MG/DAY ORAL POTASSIUM IODIDE 400 TO 800 MG/DAY ORAL PREDNISONE ORAL PREDNISONE