Breast cancer – UK The statistics in this presentation are based on the Breast CancerStats report published in 2007. However, the incidence, mortality and survival statistics have been updated to reflect the latest available data. For more information about UK cancer statistics please contact stats.team@cancer.org.uk or visit http://info.cancerresearchuk.org/cancerstats

Table One: Number of new cases and rates of breast cancer, UK, 2006   England Wales Scotland N.Ireland UK Cases Males 275 18 20 1 314 Females 38,004 2,445 4,079 980 45,508 Persons 38,279 2,463 4,099 981 45,822 Crude rate per 100,000 population 1.1 1.2 0.8 0.1 147.1 160.7 154.1 110.3 147.3 75.4 83.0 80.1 56.3 75.6 Age-standardised rate (European) per 100,000 population 0.9 1.0 0.7 CI 95% 0.5 1.4 0.4 0.0 0.2 121.4 124.4 121.7 99.2 121.0 120.2 122.6 119.4 129.3 118.0 125.4 92.9 105.4 119.9 122.1 63.9 65.7 65.3 52.4 63.8 63.2 64.5 63.1 68.3 63.3 67.3 49.1 55.7 64.4

Figure One: Numbers of new cases and age specific incidence rates, by sex, breast cancer, UK 2006 screened age group

* to the European standard population Figure Two: Figure 1.2 Age standardised* (world) incidence rates , female breast cancer in selected countries, 2002 estimates * to the European standard population

* to the European standard population Figure Three: Age standardised *(European) incidence and mortality rates, female breast cancer in EU countries, 2006 estimates * to the European standard population

* to the European standard population Figure Four: Age standardised* (European) incidence and mortality rates, breast cancer, females, GB, 1975-2007 * to the European standard population

Figure Five: Age-specific incidence rates for female breast cancer, Great Britain, 1975–2006

* to the European standard population Figure Six: European age-standardised* incidence rates of invasive breast cancer by age group in Scottish women (1980–2005), and numbers of dispensed items of HRT and raloxifene (1993–2005) * to the European standard population

Table Two: Estimated risk of developing breast cancer by age, females, UK, 2001–2005 Risk up to age 25 1 in 15,000 Risk up to age 30 1 in 1,900 Risk up to age 40 1 in 200 Risk up to age 50 1 in 50 Risk up to age 60 1 in 23 Risk up to age 70 1 in 15 Risk up to age 80 1 in 11 Risk up to age 85 1 in 10 Lifetime risk (all ages) 1 in 9

Figure Seven: Estimated cumulative incidence of breast cancer in developed countries if women had family sizes and breastfeeding patterns typical of developing countries

Relative risk (confidence interval) Oral contraceptive use Table Three: Oral contraception and the relative risk of breast cancer   Relative risk (confidence interval) Oral contraceptive use Never users 1.0 Current users 1.24 (1.15-1.33) 1-4 years after stopping 1.16 (1.08-1.23) 5-9 years after stopping 1.07 (1.02-1.13) 10+ years after stopping 1.01 (0.96-1.05)

Table Four: Relative risk of invasive breast cancer in relation to recency and type of HRT used

Table Five: Rare familial cancer syndromes associated with breast cancer

Table Six: Relative risk (95%CI) of breast cancer in categories of BMI, by menopausal status

Table Seven: UK NHS Breast Screening Programme results April 2006 to March 2007

Table Eight: The main stages of breast cancer

Figure Eight: Age-standardised one-year relative survival rate, female breast cancer, England and Wales 1971-2006

Figure Eight: Age-standardised five-year relative survival rate, female breast cancer, England and Wales 1971-2006

Figure Ten: Age-standardised ten-year relative survival rate, female breast cancer, England and Wales 1971-2000

Figure Eleven: Figure 3.4: Age-standardised twenty-year relative survival rate, female breast cancer, England and Wales, 1991-2003

Table Nine: Number of deaths and mortality rates of breast cancer, UK, 2007   England Wales Scotland N.Ireland UK Deaths Males 76 10 5 1 92 Females 9,986 637 1,062 305 11,990 Persons 10,062 647 1,067 306 12,082 Crude rate per 100,000 population 0.3 0.7 0.2 0.1 38.4 41.7 39.9 34.0 38.6 19.7 21.7 20.7 17.4 19.8 Age-standardised rate (European) per 100,000 population 0.5 CI 95% 0.8 0.0 -0.1 26.7 27.1 26.3 26.2 27.2 24.6 28.7 25.5 28.8 23.3 29.2 14.5 14.7 15.1 14.6 14.2 14.8 13.6 15.8 16.0 12.9 16.2 14.3

Figure Twelve: Number of deaths and age-specific mortality rates, breast cancer, by sex, UK, 2007

Figure Thirteen: Age-standardised Figure Thirteen: Age-standardised *(European) mortality rates, breast cancer, females, UK, 1971-2007

Figure Fourteen: Age-specific mortality rates for female breast cancer, UK, 1971–2007