Laser Accelerated Proton Beams for Radiation Therapy C-M Ma, T Tajima, B Shahine, JS Li, MC Lee, T Guerrero and AL Boyer Dept. of Radiation Oncology Stanford.

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Presentation transcript:

Laser Accelerated Proton Beams for Radiation Therapy C-M Ma, T Tajima, B Shahine, JS Li, MC Lee, T Guerrero and AL Boyer Dept. of Radiation Oncology Stanford University School of Medicine Stanford, CA 94305, USA

Why/Why Not Proton Beams? l Advantageous dosimetry characteristics l Expensive, cumbersome, inflexible l Potential remains to be explored

Laser Ion Acceleration  = 0.6 degrees

Computational and experimental proton acceleration as a function of laser intensity (Zhidkov et al. 1999).

Theoretical Results

Proton angular distribution Proton spectrum

Energy Conversion and Dose Rate

Combined dose distribution Proton spectrum

Comparison of Isodose Distribution Modulated Proton beamsPhoton IMRT

Comparison of DVH Target DVH Rectum DVH

Current Research at Stanford on Laser-Proton Beams  Particle-in-cell (PIC) simulations of laser-ion interactions  System design for a laser-proton therapy unit  Software development for accurate and fast dose calculation  Treatment optimization for energy-and intensity- modulated proton therapy (EIMPT)

For detailed dose calculation and IMPT treatment optimization, please see:  Jinsheng Li, et al., TU-C-BRA-06  Bilal Shahine et al, TU-C-BRA-07

The Stanford Monte Carlo Team Charlie Ma Gary Luxton David Findley Todd Koumrian Steve Jiang Jinsheng Li Eugene Fourkal Michael Luxton Michael Lee Jasjit Jolly Art Boyer Todd Pawlicki Ed Mok Sam Brain Thomas Guerrero Jun Deng Joerg Lehmann Meisong Ding Ajay Kapur Grisel Mora