NeSSI Compatible Spectroscopic Flow Cells Mike Doyle Axiom Analytical, Inc.
Unique Requirements of Spectroscopic Process Analysis Use of broad spectrum optical radiation Need to couple to complex remote instruments Need to produce SPC plots from large arrays of data
Comparison Of Four Forms Of Process Molecular Spectroscopy Mid-IR Near-IR UV-Visible Raman Applicable Sampling Methods ATR - liquids Transmission - gases Transmission Diffuse reflectance ATR Raman Scattering Band Types Fundamentals Overtones (CH, OH, etc) Chromophores Calibrations Easy Often Tedious Case dependent Optics Chemically sensitive Resilient Fiber-Optic Coupling Short Distances Only OK Sample Fluorescence Problematic Background Radiation Referencing
Applicability of Various Sampling Methods Sample Type Mid-IR ATR Mid-IR Transmission NIR & UV-Vis NIR Diffuse Reflectance UV-Visible ATR Raman Clear Fluids Yes Some Cases No Scattering Fluids Liquid Phase Only Powders Bulk Solids, Scattering Clear Gases
Spectroscopic Methods Appropriate to the NeSSI Platform Samples Type – Clear liquids Methods: Near-IR: Transmission UV-Visible: Transmission and ATR Raman: Backscatter Mid-IR: ATR ?
The NeSSI Platform Objectives Standardize and simplify systems for process analysis Provide a system of miniature, interchangeable sample handling components Analyzer systems close to the sampling point Short lines, fast response Modular assembly
Axiom Product Overview – Fluid Analysis Near-IR and UV-Visible Transmission Established Products FPT-850 Transmission Probes FCT Series Cross-Line Sampling Systems FFV-300 Series Transmission Cells FST-500 Unistage Transmission Sampler Most Significant Development Permanent Welded-in Metal Seals Recent Developments Self Cleaning Probes Small Diameter Probes Polymer Melt Transmission Probes NeSSI Compatible FFV Transmission Cells
FFV Series Transmission Cells Variable or fixed pathlengths
FFV-320NSI Transmission Cell
FFV-320-NSI Transmission Cell
Tunable Laser Spectra of Isopropanol with Pathlengths from 1 to 7.5 mm
Comparison of FTIR and Tunable Laser Spectra (1 and 2 mm pathlengths)
Product Overview – Fluid Analysis Attenuated Total Reflectance (ATR) Established Products Direct-coupled ATR Probes – Including diamond tipped probes ATR Flow Cells – Process and lab Tunnel Cells Fiber-coupled UV-Visible Tunnel Cells New Developments Fiber-coupled Mid-IR ATR Probes Integrated ATR Sampling Systems UV-Visible ATR Probes (in development) NeSSI Compatible UV-Visible Tunnel Cells
FNL-120 UV-Visible ATR Cell
Fiber-coupled UV-Visible Tunnel Cell
FNL-120EL Extended Length UV-Visible Tunnel Cell
FNL-120NSI UV-Visible ATR Cell
FNL-120UV-NSI UV-Visible ATR Cell
FNL-120EL Spectrum of 50% Red Food Dye
Product Overview Raman Probes Established Products Modular Raman Probes for Lab Applications – RFP-400 Series Robust Process Probes – RFP-500 Series Recent Developments Self-cleaning Raman Probes Multi-pass Raman Sampling NeSSI Compatible Raman Cells (Single- and Multi-pass)
RFP-400 Series Lab Raman Probes
Multipass Raman Probe Design
NeSSI Multipass Raman Cell
Raman Spectra of Isopropanol: Black = single pass, Red = multipass, Blue = black X 8.4
Raman Spectra of Toluene: Black = single pass, Red = multipass, Blue = Black X8.0
NeSSI Sampling System Example
NeSSI Compatible Spectroscopic Cells from Axiom Analytical, Inc. Currently Available FFV Series Transmission Cells (Near-IR, UV-Visible) FNL-120 UV-Visible ATR Cell In Development Raman Cells (Single- and Multi-pass) Possible Development Diffuse Reflectance Cells (For turbid liquids) Mid-IR ATR Cells
Engineering for the Unexpected Axiom Analytical, Inc. Engineering for the Unexpected