Adult Immunization 2010 MMR Vaccine Segment This material is in the public domain This information is valid as of May 25, 2010

Measles-Mumps-Rubella Vaccine (MMR) Contains live attenuated viruses 1-dose efficacy varies from 80% (mumps) to 95% (measles and rubella) Duration of immunity probably lifelong Schedule is 2 doses All adults born in 1957 or later should have documentation of at least 1 dose (or other evidence of immunity)

Adults at High Risk for Measles College students International travelers Healthcare personnel

MMR Vaccine Contraindications Severe allergic reaction to vaccine component or following prior dose Pregnancy Immunosuppression

Measles Vaccine and HIV Infection MMR recommended for persons with asymptomatic and minimally symptomatic HIV infection NOT recommended for persons with evidence of severe immuno- suppression Prevaccination HIV testing of an otherwise healthy person not recommended

MMR Vaccination of Women of Childbearing Age Ask if pregnant or likely to become so in next 4 weeks Exclude those who say "yes“ For others – explain theoretical risks – vaccinate

MMR Vaccine Precautions Moderate or severe acute illness Recent receipt of a blood product History of thrombocytopenia or thrombycytopenic purpura

MMR Adverse Reactions Fever5%-15% Rash 5% Joint symptoms 25% Thrombocytopenia<1/30,000 doses Parotitis rare Deafness rare Encephalopathy <1/1,000,000 doses

National Center for Immunization and Respiratory Diseases Contact Information Telephone (800) CDC-INFO Website Broadcast Updates and Resources Web Page