Yeast-based automated high-throughput screens to identify anti-parasitic lead compounds by Elizabeth Bilsland, Andrew Sparkes, Kevin Williams, Harry J.

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Yeast-based automated high-throughput screens to identify anti-parasitic lead compounds by Elizabeth Bilsland, Andrew Sparkes, Kevin Williams, Harry J. Moss, Michaela de Clare, Pınar Pir, Jem Rowland, Wayne Aubrey, Ron Pateman, Mike Young, Mark Carrington, Ross D. King, and Stephen G. Oliver Open Biology Volume 3(2): February 27, 2013 ©2013 by The Royal Society

Fluorescence labelling of yeast strains. Elizabeth Bilsland et al. Open Biol. 2013;3: ©2013 by The Royal Society

Relative fluorescence measure detected using a BMG Optima plate reader at 580 nm (excitation)/612 nm (emission) (Cherry), 405 nm (excitation)/510 nm (emission) (Sapphire), 500 nm (excitation)/540 nm (emission) (Venus) and 440 nm (excitation)/490 nm (emissio... Elizabeth Bilsland et al. Open Biol. 2013;3: ©2013 by The Royal Society

Example of a high-throughput screening result. Elizabeth Bilsland et al. Open Biol. 2013;3: ©2013 by The Royal Society

Network of connections between kinetoplastid targets and our hits. Elizabeth Bilsland et al. Open Biol. 2013;3: ©2013 by The Royal Society

Antiplasmodial hits. Elizabeth Bilsland et al. Open Biol. 2013;3: ©2013 by The Royal Society