INFLAMMATION & DEGENERATION ARTHRITIS

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Presentation transcript:

INFLAMMATION & DEGENERATION ARTHRITIS

DEFINITIONS INFLAMMATORY JOINT DISEASE IS SYSTEMIC, CAUSES STIFFNESS ALL OVER, SWELLING IN JOINTS, PAIN AND FATIGUE DEGENERATIVE JOINT DISEASE CAUSES PAIN WITH MINIMAL STIFFNESS AND SWELLING AND NO FATIGUE

DIFFERENCE STIFFNESS IS FAR GREATER IN INFLAMMATORY ARTHRITIS THAN DEGENERATIVE AND SO IS THE FATIGUE/WEAKNESS

ETIOLOGY INFLAMMATORY IS AUTOIMMUNE (RA, LUPUS), CRYSTAL INDUCED (GOUT), INFECTIOUS, METABOLIC (THYROID,PARATHYROID) DEGENERATIVE IS GENETIC, END RESULT OF INFLAMMATORY, TRAUMA, AGE...

CASE - 1 80 YEAR OLD WITH MODERATELY SEVERE BACK PAIN AFTER WALKING LESS THAN A MILE, SHE ALSO IS STIFF IN HANDS FOR 45 MIN IN AM

CASE - 2 45 YO WITH GENERALIZED SEVERE PAIN, IN ALL JOINTS AND STIFFNESS THAT LASTS FOR HRS. AFTER TREATMENT HER DEVELOPED INCREASING LEFT HIP PAIN THAT IS PROGRESSIVELY GETTING WORSE.

TREATMENT HISTORY AND PHYSICAL LAB X-RAY/MRI

TREATMENT PHYSICAL THERAPY AQUA-THERAPY FISH OIL/GLUCOSAMINE EXERCISE TOPICAL APPLICATIONS

TREATMENT GLUTEN FREE MSG, ALFALFA SPROUTS MEAT, SEA FOOD, BBQ, COOKED TOMATOES AND EGGPLANTS ALCOHOL- BEER VERSUS OTHERS

TREATMENT NSAIDs DISEASE MODIFYING DRUGS-NON BIOLOGICS DISEASE MODIFYING DRUGS-BIOLOGICS RESEARCH

TREATMENT NON BIOLOGICS EXAMPLES: MTX, SULFA, LEFLUNOMIDE, PLAQUENIL (HCQ), AZATHIOPRINE, CELLCEPT...

TREATMENT TNF BIOLOGICS: ENBREL, HUMIRA, REMICADE, CIMZIA, SIMPONI, ARIA

TREATMENT NON-TNF: ORENCIA, RITUXAN, ACTEMRA, BENLYSTA, XELJANZ,

TREATMENT HIGH RISK MEDS: EDUCATE, SCREEN, VACCINE, HYGENE