Joe Tartakoff RIT Mechanical Engineering. Paravalvular Leakage in TAVI Problem: Severity of valve calcification linked to degree of paravalvular aortic.

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Presentation transcript:

Joe Tartakoff RIT Mechanical Engineering

Paravalvular Leakage in TAVI Problem: Severity of valve calcification linked to degree of paravalvular aortic regurgitation Needs: Better adhesion for valve stenting to calcified leaflets Better devices/techniques to reduce the need for balloon redilation or second valve implantation 45,000 TAVI procedures done worldwide since start, of which 12-20% develop postprocedural PVL (severe aortic regurgitation is rare)

Endoleaks after TEVAR Procedure Problem: Endoleaks develop in 29% of all TEVAR procedures, leading to increased risk of postprocedural aneurysm rupture Needs: Develop better aortic fixation (Type I endoleaks – 40%) Develop better monitoring of aneurysm sac (Type II endoleaks – 35%) Develop better connections between graft components (Type III endoleaks – 20%) 200,000 AAA per year 30,000 TAA per year

IVC Filter Removal Problem: Successful removal of IVC filters are rare (3.7% of retrievable IVC filters are actually removed) Needs: Develop technique/device to make removal of IVC filters easier for the surgeon (better proximal-distal control) Develop a new IVC filter that can be removed easily About 200,000 IVC filters implanted per year in US (use of IVC filters has increased over the last 3 years)

Ablation in Maze Procedure Problem: MAZE procedures can be time consuming due to non-transmural ablation and variations in the heart’s nervous structure Needs: Improve the delivery and outcome of ablations Develop techniques to design individualized maze pathways Atrial fibrillation affects roughly 2.5 million people in US

VAD Power Line Problem: Transcutaneous power cable responsible for most problems with VADs (infection, cable fraying, limiting device lifetime) Needs: Stronger and more flexible cable (higher fatigue life) Reduce infection at the transcutaneous interface (tissue integration) Roughly 250,000 implanted each year (only 2,000 transplants) Existing Technology: Wireless electromagnetic induction (slow recharge time) Spiral power cable (Jarvic 2000 – still have infection)

Questions/Comments Association of aortic valve calcification severity with the degree of aortic regurgitation after transcatheter aortic valve implantation. International Journal of Cardiology. 150 (2011) pg Endoleaks after endovascular repair of thoracic aneurysms. Journal of Vascular Surgery. September 2006 pg Retrievable Inferior Vena Cava Filters are Rarely Removed. The American Surgeon. May Volume 75, Issue 5 pg The Maze Porcedure: A surgical intervention for ablation of atrial fibrillation. Heart & Lung: The Journal of Acute and Critical Care. Volume 37, Issue 6 pg