Industrial Biotech Careers ©UF/CERHB

Industrial Biotechnology Biotech means business: The biotechnology industry has surpassed the pharmaceutical industry as the primary source of new medicines in the U.S.* Between 1992 and 2003, U.S. health care revenues from biotechnology increased from $8 billion to $39 billion – 400%** The total value of publicly traded U.S. biotech companies in 2005 was $311 billion** Source: Ernst & Young LLP, 2006 Source: Biotechnology Industry Organization (BIO,) 2006 Source: Biotechnology Industry Organization (BIO,) 2006 *Ernst & Young 2006 **BIO 2006 ©UF/CERHB

Industrial Biotechnology Products include: Biopharmaceuticals/biologics Medicinal or therapeutic In vivo Medical devices Medical implements In vitro diagnostics, including test kits and instruments Functions are non-metabolic Investigative research instruments and materials Food production and testing Enzymes, DNA analysis, species and safety testing

Industrial Biotechnology Supports many careers: R&D QC QA Manufacturing Regulatory Affairs Facilities Resource Management Sales Service and Support Finance Marketing Public Relations IT Each of these categories has sub-categories. One of the broadest ones is R&D, because that could be drug development, assay development, instrument development, software development, etc. Service and Support could be customer service, technical support, field service, training, etc. QC could be Environmental Monitoring, process/product testing, equipment testing, Contracts could be purchasing, selling, legal work, etc. There are tracks unique to the field and career paths you can find in any business or organization. Education and skill requirements will vary depending on the position. ©UF/CERHB

Industrial Biotechnology Products include: Biopharmaceuticals/biologics Medicinal or therapeutic In vivo Medical devices Medical implements In vitro diagnostics, including test kits and instruments Functions are non-metabolic Investigative research instruments and materials

Industrial Biotechnology Biotech instrumentation: Major resource and product in the biotechnology ecosystem Numerous industrial, clinical, and academic applications Integral to rapid increases in productivity, consistency, and accuracy ©UF/CERHB

Industrial Biotechnology Research instruments: Example: QIAGEN, Inc. QIAsymphony Human, viral and bacterial DNA, RNA, protein purification Automated sample transfer, lysis, washing, elution High quality, throughput, and standardization

Industrial Biotechnology Clinical instruments: Example: Siemens Microscan Walkaway Automatic incubation, reagent addition, and test interpretation of clinical bacteriology specimens Up to 96 species ID and antibiotic sensitivity results in 24 hours

Industrial Biotechnology Medical instruments: Example: GE Signa HDxt 3.0T MR Higher resolution for improved diagnosis and image-guided treatment Functional and spectroscopic imaging Key role in monitoring cellular therapeutics Is this a biotechnology instrument? Referred to in “Trends in Biotechnology” on cell.com. Function MRI being used in cell tracking, intracellular labels, cell labels, and in vivo quantification. So it is related. ©UF/CERHB

Industrial Biotechnology Instrumentation lifecycles: 1. Conception 2. Market assessment 3. Engineering and Development 4. Manufacturing and Testing 5. Marketing and Sales 6. Deployment 7. Service and Support 8. Decommission Pick an instrument and describe it’s path through the lifecycle. If the instrument is a medical device, it will require FDA approval before going to market. Research-use-only instruments avoid this requirement. “Testing” includes safety and conformity testing, e.g. UL and CE (conformite europeenne) marking. ©UF/CERHB

Industrial Biotechnology Instrument companies: Need mechanically inclined staff to help develop, produce, test, sell, service, and support their instruments Provide new hires with the specialized training needed to succeed in their positions Offer competitive salaries, benefits, and advancement opportunities

Industrial Biotechnology Supports many careers: R & D QA QC Regulatory Affairs Manufacturing Facilities Resource management Sales Service & Support Finance Marketing Public Relations IT ©UF/CERHB

Industrial Biotechnology Staff placement: R&D, QC, manufacturing, and in-house repair positions located at headquarters and/or production facilities Sales, field application support, and field service positions are regional Number of regions depends on number of placed instruments Can work for a Maryland based company and still live in Florida ©UF/CERHB

Industrial Biotechnology Applied Biosystems GE Baxter Millipore Beckman Coulter Nova Barnstead Qiagen Becton Dickinson Roche All of these companies have instrument placements in Florida, either at hospitals, outpatient facilities, diagnostic laboratories, universities, or other research facilities. There are more like them! Bio-Rad Siemens Eppendorf Thermo Fisher ©UF/CERHB

Industrial Biotechnology Resources: Company websites Hospitals Biomedical positions BioFlorida www.bioflorida.com Florida Biotechnology News www.floridabiotechnews.com

Industrial Biotechnology Biotech education/training contacts: UF-CERHB Tammy Mandell (tmandell@cerhb.ufl.edu) Lori Wojciechowski (lwojo@ufl.edu) Mark Leone (mleone@cerhb.ufl.edu) www.cerhb.ufl.edu/education Indian River State College Casey Lunceford (cluncefo@irsc.edu) Palm Beach State College Libby Handel, Ph.D. (handele@palmbeachstate.edu) Contacts for Equipment training? ©UF/CERHB