Cell Signaling How cells communicate.

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Presentation transcript:

Cell Signaling How cells communicate

Learning Objectives How do cells communicate long and short distances? What are the 3 stages of cell signaling? What is involved in each of the 3 stages of cell signaling?

Cell Communication Video http://www.bozemanscience.com/037-cell-communication

Signaling Direct Contact Paracrine Synaptic Local Regulators Cell junctions Cell-cell recognition Paracrine Growth factors cause cells to grow and multiply Synaptic Nervous system Electrical signal triggers chemical signal – neurotransmitters

Signaling Hormones Long-Distance “endocrine signaling” Cells release hormone molecules into blood vessels where they travel to other parts of the body Plant hormones can travel through cells, or through air as a gas Vary a lot in size & type: ethylene vs. insulin

Three Stages of Cell Signaling 1. Reception A chemical signal is “detected” when it binds to a receptor protein on the cell’s surface or inside the cell. Three Stages of Cell Signaling A Preview…

Three Stages of Cell Signaling 2. Transduction The receptor protein changes in response to the signal and initiates the process of converting the signal to a form that can bring about the response. Can be a single step or a sequence of changes in multiple molecules (“signal transduction pathway”) Three Stages of Cell Signaling A Preview…

Three Stages of Cell Signaling 3. Response Any cellular activity Must happen in the right cells, at the right time, and in coordination with other cells of the organism Three Stages of Cell Signaling A Preview…

Signal Transduction Video http://www.bozemanscience.com/038-signal-transduction-pathways