NOVEL APPROACHES FOR BIOTECHNOLOGY TRAINING AT COMMUNITY COLLEGES Linda R. Rehfuss May 6, 2007 Boston, MA

Biotechnology Education Biotechnology programs offered since Fall Biotechnology programs –A.S., designed for transfer –A.A.S., career track –A.A.S. in Biotechnology, Nanobiotechnology option (4 th semester capstone at Penn State) 5 Biotechnology-specific courses developed

MCCC Biotech Students

Advanced Technology Center (ATC)

New Lab in ATC

MCCC Biotech Program 5 Biotech-specific courses: –Introduction to Biotechnology - recombinant DNA, drug discovery process, patents –Basic Techniques for Biotechnology - pH, micropipettors, UV spec –Biotechnology Research - recombinant DNA techniques, PCR, genetics –Biotechnology Manufacturing - GMP regulations, QA and QC –Biotechnology Internship - field experience

2+2+2 Partners Technical High Schools: –North Montco Technical Career Center –Center for Technical Studies of Mont. Cty. Community Colleges: –Montgomery County Community College –Bucks County Community College –Community College of Philadelphia 4 Year Colleges and Universities: –Thomas Jefferson University –Cabrini College –Penn State – Abington College

Activities Students from Vo-tech schools summer camps Teacher training programs Workforce Investment Board (WIB)

Education Collaborators Kevin Lampe, Assistant Professor of Biotechnology, MCCC Christopher Harendza, Ph.D., Professor of Biology, MCCC Evon Martins, Ph.D., Assistant Professor of Chemistry Laura McAtee, Ph.D., Instructor of Chemistry, MCCC Lori Dodson, Ph.D., Biotechnology Instructor, North Montco Technical Career Center, Lansdale, PA Rich Coletta, Biotechnology Instructor and Program Development, Center for Technical Studies of Montgomery County, Plymouth Meeting, PA Esther E. Biswas-Fiss, Ph.D., Associate Professor and Program Director in Biotechnology, Thomas Jefferson University, Philadelphia, PA Sheryl L. Fuller-Espie, Ph.D., DIC, Associate Professor of Biology, Science Department Chair, Cabrini College, Radnor, PA Melanie Lenahan, Ph.D., Assistant Professor and Program Director in Biotechnology, Raritan Valley Community College, Somerville, NJ Randy Libros, Associate Professor of Physics, Community College of Philadelphia, Philadelphia, PA Laura Anne Roselli, Instructor and Program Consultant for Biotechnology, Burlington County College, Mt. Laurel, NJ

Industry Collaborators Thomas Hartnett, P.E., Sr. Director of Engineering, Pharmaceutical Sourcing Group of the Americas, Johnson and Johnson Family of Companies, Bridgewater, NJ Joseph P. Lingle, P.E., Director, Facilities Operations, GlaxoSmithKline, King of Prussia, PA Thomas B. Lavoie, Ph.D., Section Head, Protein Biochemistry, PBL Biomedical Laboratories, Piscataway, NJ Peter Lowry, Vice President, Operations, The Immune Response Corporation, King of Prussia, PA Thom Moll, Manager, Fluids Manufacturing Area, Merck and Co., Inc., West Point, PA Cynthia Sarnoski, Ph.D. Sr. Vice President, Global Quality Assurance, Wyeth, Collegeville PA Richard P. Schwartz Jr., Ph.D., President, CV Ventures, LLC, Blue Bell, PA Dr. Carol Adukaitis, WLG Program Manager, PA State System of Higher Education, Harrisburg, PA Life Science Career Alliance, Philadelphia, PA Collegiate Consortium

Partnership with Rohm and Haas R & H Chemical company with Healthcare division Developed polymeric separation media Trying to extend platform technologies Want to use media for purification of high molecular weight drugs Partner with MCCC in the ATC for project

R & H –MCCC Partnership Benefit to Company:  Polymers tested in biological systems (R & H doesn’t have cell culture capabilities)  Extend product capability  Materials produced and tested in R & H facilities  Trained students for internships and future employees

R & H –MCCC Partnership Benefit to College:  Well trained students – college paid “internship”  ATC use  Students versed in a variety of techniques and equipment  Students provided on-site training at R & H as well in analytical techniques  Growing the reach of NBC 2

Merck-MCCC Partnership Vaccine division collaboration Aseptic awareness course 1 week for new hires; 1-2 day for incumbent workers Attributes sought: gowning, behavioral practices, skills used in aseptic manufacturing ATC collaboration as well

Merck-MCCC Partnership Students may participate – compliments their didactic and in class laboratory instruction Extends company-college-community reach Provided through non-credit opportunities at the College Pilot with Merck could be extended to other companies

Teacher Training Institute STEM disciplines at College: Biotechnology, Biology, Chemistry, Physics, Engineering, Math Grades 7-12 and Community College teachers and faculty Teachers participate in R&H and Merck projects – help them prepare their students

Funding for Projects offered at the College NSF (preliminary proposals and current grant) DOL Company (R &H, Merck) Private investors State funds ANYONE WITH OTHER FUNDING IDEAS?

Where Are MCCC Interns & Grads?

10 Critical Biomanufacturing Jobs for NBC 2 Process Development Associate Validation Specialist Manufacturing Technician - Upstream Manufacturing Technician - Downstream Instrumentation/Calibration Technician Chemistry QC Technician Microbiology QC Technician Environmental Health & Safety Technician QA Documentation Coordinator Facilities Technician

MCCC Contact Information Linda Rehfuss, Ph.D. Montgomery County Community College 340 DeKalb Pike Blue Bell, PA Kevin Lampe, M.S. Assistant Professor of Biotechnology