A TWO YEAR OLD GIRL WITH PROGRESSIVE WEAKNESS Teaching NeuroImages Neurology Resident and Fellow Section © 2014 American Academy of Neurology.

Slides:

Advertisements

Similar presentations

MOTOR NEURON DISEASE The motor neuron diseases (or motor neuron diseases) (MND) are a group of neurological disorders that selectively affect motor neurons.

Advertisements

Clinical applications

It’s the major control unit of the body. It controls your thinking, memory, and you learning. It detects changes in the body. Controls all muscle activities.

Teaching NeuroImages Neurology Resident and Fellow Section © 2013 American Academy of Neurology A 68 year old woman with transient ptosis on awakening.

Teaching NeuroImages Neurology Resident and Fellow Section © 2013 American Academy of Neurology Intracranial mass presenting with hemorrhage and respiratory.

A 56-year-old man with intense facial pain Teaching NeuroImages Neurology Resident and Fellow Section © 2014 American Academy of Neurology.

A 41 year old African patient with „multifocal neurology“ Teaching NeuroImages Neurology Resident and Fellow Section © 2013 American Academy of Neurology.

A 62-year-old man with progressive action tremor and a 74-year-old man with progressive ataxia Teaching NeuroImages Neurology Resident and Fellow Section.

Teaching NeuroImages Neurology Resident and Fellow Section A 57-year-old woman with blurred vision © 2014 American Academy of Neurology.

Acute neck pain and quadriparesis An 82 year old man with acute neck pain Teaching NeuroImages Neurology Resident and Fellow Section © 2014 American Academy.

48-year-old man with ascending sensory deficits Teaching NeuroImages Neurology Resident and Fellow Section © 2014 American Academy of Neurology.

A 48-year-old man with ptosis and limitation of elevation in the left eye © 2014 American Academy of Neurology Teaching NeuroImages Neurology Resident.

A 68 year old woman with a troublesome chin tremor Teaching NeuroImages Neurology Resident and Fellow Section © 2013 American Academy of Neurology.

84 year old woman with spells of right upper limb weakness and numbness Teaching NeuroImages Neurology Resident and Fellow Section © 2014 American Academy.

Muscle cramps and a raised creatine kinase. Teaching NeuroImages Neurology Resident and Fellow Section © 2013 American Academy of Neurology.

A patient with red dot on the forehead A 32-year old woman presented with red dot on her forehead and eyelid ecchymosis Teaching NeuroImages Neurology.

Teaching NeuroImages An 83-year-old woman with phonatory breaks and left hand rest tremor Neurology Resident and Fellow Section © 2013 American Academy.

A 30 year old man with sub-acute ataxia Teaching NeuroImages Neurology Resident and Fellow Section © 2014 American Academy of Neurology.

Neurology Resident and Fellow Section 40 year old woman with left arm pain, numbness, and weakness Teaching NeuroImages © 2013 American Academy of Neurology.

Teaching NeuroImages Neurology Resident and Fellow Section © 2013 American Academy of Neurology A 3-year-old boy with silvery gray hair and leukodystrophy.

Cases Neuroscience. Case 4 A 45 year old woman with a history of hypertension experienced a brief "blackout". She had complained of severe headaches,

Teaching NeuroImages Neurology Resident and Fellow Section © 2013 American Academy of Neurology A 14 year old male with headache and neck stiffness.

A 17-year-old girl with encephalomyelitis Teaching NeuroImages Neurology Resident and Fellow Section © 2015 American Academy of Neurology.

MOTOR THE WORD MOTOR MEANS M O V E M E N T MOTOR SYSTEM INCLUDES MOTOR CORTEX PYRAMIDAL TRACTS CORTICO SPINAL CORTICO BULBAR EXTRA PYRAMIDAL TRACTS BASAL.

Teaching NeuroImages Neurology Resident and Fellow Section © 2013 American Academy of Neurology A 54 year old man with progressive apathy and cognitive.

A 50 year old man with progressive tetraparesis and blindness Teaching NeuroImages Neurology Resident and Fellow Section © 2013 American Academy of Neurology.

47-year-old with progressive upper limb weakness Teaching NeuroImages Neurology Resident and Fellow Section © 2014 American Academy of Neurology.

Neurology Department of Neurology, The 2nd affiliated hospital,

A 39-year old man with facial diplegia Teaching NeuroImages Neurology Resident and Fellow Section Campbell J, et al © 2013 American Academy of Neurology.

Teaching NeuroImages Neurology Resident and Fellow Section © 2014 American Academy of Neurology A 23 month old full term male with seizures.

68 year old man with aphasia and facial droop © 2014 American Academy of Neurology Teaching NeuroImages Neurology Resident and Fellow Section.

Teaching NeuroImages A 54-year-old man with progressive muscle weakness, hand tremor, tongue and perioral fasciculation Neurology Resident and Fellow Section.

Teaching NeuroImages Neurology Resident and Fellow Section © 2013 American Academy of Neurology A 32-year-old man with a neuroendocrine disorder.

Amyotrophic lateral sclerosis

A 22 years old man with slow movements and mounding phenomenon © 2013 American Academy of Neurology Teaching NeuroImages Neurology Resident and Fellow.

A 26 year old woman with headache, diplopia, and pulsatile tinnitus Teaching NeuroImages Neurology Resident and Fellow Section © 2013 American Academy.

40 year old male with shooting type of pain in the lower leg Teaching NeuroImages Neurology Resident and Fellow Section © 2013 American Academy of Neurology.

Teaching NeuroImages Neurology Resident and Fellow Section © 2014 American Academy of Neurology A 67 year-old man with progressive facial diplegia and.

A 4 Year Old Boy With Proptosis of Left Eye Teaching NeuroImages Neurology Resident and Fellow Section © 2014 American Academy of Neurology.

52yo male with multiple lower cranial neuropathies Teaching NeuroImages Neurology Resident and Fellow Section by Nathaniel M. Schuster, Stellios Karnezis,

Teaching NeuroImages Neurology Resident and Fellow Section A 77 year-old woman with Parkinson’s disease exhibits re- emergent jaw tremor. © 2015 American.

A 71 year old man with rapid onset of anterograde amnesia Teaching NeuroImages Neurology Resident and Fellow Section © 2015 American Academy of Neurology.

Teaching NeuroImages 38 years old female with leg pain and weakness Neurology Resident and Fellow Section.

Neurological Examination Dr Andrew Gale 23 Feb 2010.

Lecture by DR SHAIK ABDUL RAHIM

Motor Pathways Dr Ayman G. Abu-Tabanja.

2 year old girl with mild ataxia and truncal dystonia Teaching NeuroImages Neurology Resident and Fellow Section © 2014 American Academy of Neurology.

Teaching NeuroImages Neurology Resident and Fellow Section © 2013 American Academy of Neurology Two sisters with scapular winging.

A 36 year old woman with diplopia Teaching NeuroImages Neurology Resident and Fellow Section © 2015 American Academy of Neurology.

Upper motor neuron versus lower motor neuron Lower motor neurons are the anterior gray horn cells (alpha motor neuron) in the spinal cord and the motor.

A 35-year-old patient with motor aphasia Teaching NeuroImages Neurology Resident and Fellow Section © 2013 American Academy of Neurology.

A 71-YEAR-OLD FEMALE WITH MULTIPLE CRANIAL NERVE PALSIES

Hemigeographic tongue following an acute ischemic stroke

Neurology Resident and Fellow Section

Teaching NeuroImages Neurology Resident and Fellow Section

Amyotrophic Lateral Sclerosis (ALS)

A 17 year old male with tremors and wasting of both hands

Teaching Video NeuroImages Neurology Resident and Fellow Section

A 22-year-old woman with progressive ataxia and feet dystonia

A 41-year-old man with progressive quadriparesis

A 58-year-old man with progressive stiffness

A 22 year old woman with progressive vision loss

Resident and Fellow Section

Neurology Resident and Fellow Section

Presentation Sajjad Ahmad Topic Flaccid Paralysis Topic Flaccid Paralysis.

A 45 YEAR OLD WOMAN WITH PROGRESSIVE WEAKNESS

Neurology Resident and Fellow Section

A 45 year-old man with a pathognomonic dyskinesia

A 2 year old girl with progressive neurological deficits

Presentation transcript:

A TWO YEAR OLD GIRL WITH PROGRESSIVE WEAKNESS Teaching NeuroImages Neurology Resident and Fellow Section © 2014 American Academy of Neurology

Vignette This is a two year-olf girl with progressive weakness and hypotonia since birth. Deep tendon reflexes are absent. Her tongue presents very frequent fasciculations. Good eye contact, and normal cognition. Montenegro MA © 2014 American Academy of Neurology

Imaging Montenegro MA © 2014 American Academy of Neurology

Tongue Fasciculations in Spinal Muscular Atrophy Spinal muscular atrophy (SMA) is a heterogeneous, autosomal-recessive neuromuscular disorder. It affects the lower motor neurons. It is characterized by loss of the anterior horn cells in the spinal cord and cranial nerves nuclei. Patients present weakness and muscle wasting. Fasciculations are usually present, especially in the tongue (see video). Montenegro MA © 2014 American Academy of Neurology