04.10 The Sodium-Potassium Pump

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04.10 The Sodium-Potassium Pump Slide number: 1 Extracellular fluid with high concentration of Na+ Na+ K+ Na+ ATP ADP P P K+ Cytoplasm with high concentration of K+ P 1 Three Na+ bind to the cytoplasmic side of the protein. 2 Phosphate is transferred from ATP to the protein. 3 Phosphorylation changes the shape of the protein, moving Na+ across the membrane. 4 K+ binds to the protein, causing phosphate release. 5 Release of phosphate changes the shape of the protein, moving K+ to the cytoplasm. Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

04.10 The Sodium-Potassium Pump Slide number: 2 Extracellular fluid with high concentration of Na+ 1 Three Na+ bind to the cytoplasmic side of the protein. Na+ Cytoplasm with high concentration of K+ Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

04.10 The Sodium-Potassium Pump Slide number: 3 Extracellular fluid with high concentration of Na+ 1 Three Na+ bind to the cytoplasmic side of the protein. 2 Phosphate is transferred from ATP to the protein. ATP ADP P Cytoplasm with high concentration of K+ Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

04.10 The Sodium-Potassium Pump Slide number: 4 Extracellular fluid with high concentration of Na+ 1 Three Na+ bind to the cytoplasmic side of the protein. 2 Phosphate is transferred from ATP to the protein. Na+ 3 Phosphorylation changes the shape of the protein, moving Na+ across the membrane. P Cytoplasm with high concentration of K+ Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

04.10 The Sodium-Potassium Pump Slide number: 5 Extracellular fluid with high concentration of Na+ 1 Three Na+ bind to the cytoplasmic side of the protein. 2 Phosphate is transferred from ATP to the protein. K+ 3 Phosphorylation changes the shape of the protein, moving Na+ across the membrane. 4 K+ binds to the protein, causing phosphate release. P Cytoplasm with high concentration of K+ Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

04.10 The Sodium-Potassium Pump Slide number: 6 Extracellular fluid with high concentration of Na+ 1 Three Na+ bind to the cytoplasmic side of the protein. 2 Phosphate is transferred from ATP to the protein. 3 Phosphorylation changes the shape of the protein, moving Na+ across the membrane. 4 K+ binds to the protein, causing phosphate release. K+ 5 Release of phosphate changes the shape of the protein, moving K+ to the cytoplasm. Cytoplasm with high concentration of K+ Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

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