FOR RESEARCH USE ONLY CONFIDENTIAL Page 1 Enabling Digital Pathology Enabling Digital Pathology September 2007

FOR RESEARCH USE ONLY CONFIDENTIAL Page 2 About BioImagene Mission To enable affordable digital pathology for every pathologist in every hospital and laboratory worldwide Our Business To provide total digital pathology solutions for clinical diagnostics and drug discovery, using innovations in technology and bio sciences BioImagene’s digital pathology solution Fully integrated hardware and software systems to acquire, view, analyze, manage, archive and share tissue images in a pathology laboratory Customers Leading Reference Labs, Clinicians, Pharmaceutical companies

FOR RESEARCH USE ONLY CONFIDENTIAL Page 3 BioImagene, Inc.  Founded in Jan 2003, HQ in Silicon Valley, software development and research center in Pune, India  Team of around 75 professionals globally  Acquired Scimagix Inc, leader in Image Management in Nov 2004  Acquired TissueInformatics Inc, leader in toxicological image analysis provider in June  users

FOR RESEARCH USE ONLY CONFIDENTIAL Page 4 Research Diagnostics Applications 3i Framework Drug Development Drug Development Discovery Diagnosis Prognosis Tissue Slides Markers : H&E, IHC, ISH, & FISH….. TissueMine TM Pathiam TM Image Management Distributed Image Processing Image Analysis Regulatory Module – 21 CFR Part 11 Compliant Image Reference Library Tissue Types : Breast, Postrate, Liver, Colon… Total Digital Pathology Solution Architecture

FOR RESEARCH USE ONLY CONFIDENTIAL Page 5 Total Digital Pathology Solution Tissue sample preparation Reagents CaptureManageAnalyzeReport/Share Mine Interpret Collaborate Digitize Services Efficiency | Accuracy | Consistency | Low Cost | Enables Audits  Breast Panel Analysis  Prostate Panel Analysis  Colon Panel Analysis  IHC Membrane Quantification  IHC Cytoplasmic Quantification  IHC Nuclear Quantification Pathiam™/TissueMine™ Digital Pathology Application On board the iScan

FOR RESEARCH USE ONLY CONFIDENTIAL Page 6 PATHIAM™ RUO  Image Analysis Breast Panel (included); FDA Cleared Her2 image analysis Prostate Panel (optional) Colon Panel (optional)  Image Management Report generation with user selected images Share images in real time online, chat function Search functionality for finding old images/cases Add annotations to images Record measurements 21CFR11 compliant Optional LIS/LIMS integration  Image Acquisition - iScan™ Resolution; 20X and 40X Automated 160 capacity slide loader (1x3 slide format) Eight (8) Sakura rack holders for 1x3 slide format Four (4) rack holders for 2x3 slide format 1D and 2D Barcode support Label image capture Small footprint (18” x 18” x 17”)

FOR RESEARCH USE ONLY CONFIDENTIAL Page 7 TissueMine™  Image Analysis IHC nuclear quantification IHC cytoplasmic quantification IHC membrane quantification TMA gridding tool  Image Management Report generation with user selected images Share images in real time online, chat function Search functionality for finding old images/cases Add annotations to images Record measurements 21CFR11 compliant Optional LIS/LIMS integration  Image Acquisition - iScan™ Resolution; 20X and 40X Automated 160 capacity slide loader (1x3 slide format) Eight (8) Sakura rack holders for 1x3 slide format Four (4) rack holders for 2x3 slide format 1D and 2D Barcode support Label image capture Small footprint (18” x 18” x 17”)

FOR RESEARCH USE ONLY CONFIDENTIAL Page 8 Investments  TissueMine™ Express ($99,000)  Image management  Image analysis Desktop ($49,000)  Image management  Image acquisition Desktop ($99,000)  Image management  Image analysis  Image acquisition  Pathiam™ RUO $0.99 per image created $9.99 per image analyzed Minimums  Monthly rate  Term