Improving Animal and Human Health by Accelerating Veterinary Centered Entrepreneurship

Texas A&M Commercialization In 17 years have processed 2400 invention disclosures In the top 10 in the US in agreements generating revenue Received more than $60 million in royalties Complete a license once a week

The Vet School 10 percent of US practicing vets are Texas A&M graduates Small animal clinic and large animal hospital see patients from all over the US Research and discoveries in many aspects of animal health Where are the intersections?

Entrepreneurial Opportunities Increase the connection between industry and the university Translate discoveries in animal health to human health Translate discoveries for human health to animal health Recognize service business opportunities

Texas A&M Institute for Preclinical Studies Basic research Animal testing Clinical trials VISION - to become the leading facility to conduct comprehensive preclinical/GLP large animal studies that will improve the efficacy and efficiency of drug and device development with translational research

Three Main Objectives 6 GLP/pre- clinical studies Molecular and Translational Imaging Spontaneous animal disease

TIPS Facility 112,000 sq feet -state-of-the art large animal hospital -acute housing for 240 large animals; pasture/barn for long term holding -advanced imaging center -incubator space for start-up companies -office of technology commercialization

Research Endeavors  Cardiovascular devices  Emergency medicine  Orthopedics  Oncology  Stem cell research; regenerative medicine  Imaging  Nanotechnology/therapeutics/drug delivery  Spontaneous Animal Models

9 Only 17 universities in the US currently offer programs for regulatory affairs degrees or certificates Northeast, west coast, and one in Georgia. GLP training and study director training limited to in-house customized programs, contract training, or CE at trade conferences.

TIPS Collaborations

From Animal to Human Animal feed additive (special clay) –Absorbs mycotoxins –Sold under brand name Novasil –Generated $500,000 in royalties Recognized impact on intractable diarrhea –Developed a human health company –Has raised more than $2 million –Now in human trials

Human Health to Animal Health Utilizing spontaneous animal disease models –Human health discoveries can treat animals first Especially true with devices Novel drug delivery platforms Novel cancer therapeutic techniques

Service Opportunities Follow examples from human health –Allogenic stem cell techniques for animal health Improve upon existing business models like Vet Stem –Clinic and patient management software

Make an Impact Think like an entrepreneur –Connect your research to industry –Connect to the commercial pathway for research outcomes Become involved with technology transfer –Transfer your inventions and know how –May need to drive the process Help to turn discoveries into products –Impact animal and human health