By: Colleen Carter Biochemistry Spring 2012

DEPRESSANT MOST ABUSED DRUG PSYCHOACTIVE SUPPRESSES CENTRAL NERVOUS SYSTEM ALOCHOL

CONSUMPTION ABSORPTION stomach and small intestine: gastrointestinal tract DISTRIBUTION (DIFFUSION) concentration gradients ELIMINATION through pores and urination GENERAL METABOLISM

ALCOHOL CANNOT BE STORED: Must be Oxidized !

 Genetics  Culture  Psychologically  Mentally/Emotionally  Physical  Potential liver disease  Malnutrition  Most common disease in the US  Interferes with everyday life  Liver reaches a saturation point  Acetaldehyde accumulation  Mitochondrial dysfunction ALCOHOLISM

FETAL ALCOHOL SYNDROME  5 out of 1,000 births  Indicatiors: stunted growth, CNS dysfunctions, these facial characterics

Campbell, M. K., & Farrell, S. O. (2012). Biochemistry (7th ed.). Belmont, CA: Brooks/Cole. National Institute on Alcohol Abuse and Alcoholism. Accessed on: May 7 th, National Center for Biotechnology Information. Accessed on: May 7 th, 2012http:// Svensson, S., Some, M., Lundsjö, A., Helander, A., Cronholm, T. and Höög, J.- O. (1999), Activities of human alcohol dehydrogenases in the metabolic pathways of ethanol and serotonin. European Journal of Biochemistry, 262: 324–329. doi: /j x REFERENCES