معمل البكتيريا التاسع Antibiotics. تأثير المضادات الحيوية على نمو البكتيريا Effect of Antibiotics on Bacterial Growth المضادات الحيوية Antibiotics هي.

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Presentation transcript:

معمل البكتيريا التاسع Antibiotics

تأثير المضادات الحيوية على نمو البكتيريا Effect of Antibiotics on Bacterial Growth المضادات الحيوية Antibiotics هي مواد تنتج من كائنات دقيقة لقتل كائنات دقيقة أخرى ذات اهمية لعلاج الامراض الميكروبية Infectious Diseases

اقسام المضادات حسب طريقة تأثيرها على البكتيريا مضادات مثبطة للجدار الخلوي Cell Wall Inhibition B-lactams – Glycopeptides - Bacitracin – Cephalosporin المضادات المثبطة لتخليق البروتين Protein Synthesis inhibition 30S ribosomal : Tetracyclines- Aminoglycosides 50S ribosomal: Erythromycin- Chloramphenicol المضادات المغيرة لوظيفة الغشاء البلازمي Polymyxin المضادات المؤثرة على بعض العمليات الايضية في الخلية SXT المضادات المثبطة لتخليق الاحماض النووية Nucleic acid inhibition DNA: Quinolones RNA: Rifampicin

Different antibiotics destroy bacteria in different ways. Some short- circuit the processes by which bacteria receive energy. Others disturb the structure of the bacterial cell wall, as shown in the illustration above. Still others interfere with the production of essential proteins. (Illustration by Electronic Illustrators Group.)

Animation Illustrating the Role of Penicillins in Blocking Transpeptidase Enzymes from Assembling the Peptide Cross-Links in Peptidoglycan

Mechanisms of aminoglycoside. Aminoglycoside (AG) entry into cell results in cell death by either caspase-dependent or caspase-independent mechanisms.

Antibiotic Resistance

اختبار حساسية البكتيريا للمضادات الحيوية Sensitivity of Bacteria to Antibiotics Disc Diffusion Method Kirby bower technique Modified Stock Technique