Jacob Mirman, MD B.A. in Chemistry, University of MN B.A. in Chemistry, University of MN M.D., University of MN Medical School M.D., University of MN Medical School Board Certified in Internal Medicine Board Certified in Internal Medicine Founding member and Registrar of Minnesota Homeopathic Association Founding member and Registrar of Minnesota Homeopathic Association

Synaptic malfunction disorders (Neurotransmitter Deficiency Disorders) DepressionAnxietyFibromyalgiaMigrainesObesityADD/ADHDOCD Jacob Mirman, MD

The Big Picture: Hardware vs. Software Jacob Mirman, MD

12 year old boy w/ ADHD. Can’t focus on schoolwork, restless. Poor grades. Special ed. Teachers want him on drugs 12 year old boy w/ ADHD. Can’t focus on schoolwork, restless. Poor grades. Special ed. Teachers want him on drugs Rx. Stramonium 1M 1 dose Rx. Stramonium 1M 1 dose 3 months later special ed teacher comes to visit the practice unannounced. She wants to know what kind of magic we do that a kid suddenly improves to the point she can discharge him from her program.

10 year old adopted girl w/ ADHD 3 months later on NR protocol: “Hi Dr. Mirman, I just wanted to send you a quick note telling you how amazing G. is doing!! I absolutely cannot believe the difference. She is calm, focused, enjoyable, loving, non-confrontational, willing to try new things….I could go on and on. The chaos that had become our family life is gone—no more walking on egg shells. She is no longer grumpy, falling apart and no more melt downs! It is simple awesome! Thank you so much for the good working you are doing! You’ve helped change our lives in a very positive way”.

Neurotransmitters: Serotonin Dopamin Norepinephrine ProzacPaxilCelexaLexaproZoloftSerzoneWellbutrin MeridiaPhentermineFen-Phen Concerta Ritalin Adderal Strattera Methamphetamine Cocaine

Neurotransmitters L-tryptophane --> 5HTP --> Serotonin L-tyrosine --> L-dopa --> Dopamine --> --> Norepinephrine --> Epinephrine L-Cysteine L-Cysteine

Treatment Protocol Level 1: 5HTP 300mg + Tyrosine 3,000mg Level 1: 5HTP 300mg + Tyrosine 3,000mg Level 2: 5HTP 600mg + Tyrosine 4,000mg Level 2: 5HTP 600mg + Tyrosine 4,000mg Level 3: 5HTP 900mg + Tyrosine 5,000mg Level 3: 5HTP 900mg + Tyrosine 5,000mg Urine test  adjust component doses based on dynamic changes of urinary neurotransmitter levels from dose changes Urine test  adjust component doses based on dynamic changes of urinary neurotransmitter levels from dose changes

HAHNEMANN MEMORIAL, WASHINGTON DC Dedicated by President McKinley, June 1900

HOMEOPATHY SIMILIA SIMILIBUS CURENTUR Let likes be cured by likes

2 year old with fears Rx. Stramonium 1M once Child starts exploring

1 year old child w/ high fever Rx. Pulsatilla 30C every hour for 6 hours: no change Rx. Belladonna 30C every hour. Better within an hour, almost fine by morning.

3 year old with failure to strive, poor eating, undigested stool, delayed speech, delayed growth Rx. Ant-c LM1 daily Slow improvement: better eating, more normal stool, more happy, perky, speech improves, growth improves to normal

14 year old girl w/ painful periods, “teenage emotions” worse before periods, school difficulties. Family stressed out by her condition Rx. Spigelia LM1 daily Slow improvement over a year: resolution of dysmenorrhea, emotional improvement, family very happy. Treated for 1 year, then stopped and doing well.

15 year old boy w/ diagnosis of ADHD: school difficulties, grades slipping, hard to concentrate and focus. Teachers suggesting Ritalin Rx. NR protocol level 1 Fast improvement within a week. Better focusing, concentration, better grades. Continues on the pills

17 year old girl w/ diagnosis of IBS and anxiety Rx. NR protocol level 1: no improvement in 1 week,raised to level 2 Fast improvement within a week. Resolution of abdominal pains/cramping, anxiety. Continues on the pills

The Big Picture Supplements: simple, often fast, very effective, pricey, paliative Supplements: simple, often fast, very effective, pricey, paliative Homeopathy: difficult, slow, more comprehensive, different measure of effectiveness, less expensive in the long run, curative Homeopathy: difficult, slow, more comprehensive, different measure of effectiveness, less expensive in the long run, curative

Jacob I. Mirman Life Medical 4201 Excelsior Blvd St. Louis Park, MN