Sodium and Renin Angiotension System Mohammad Saifur Rohman. MD. PhD. FIHA Dept. of cardiology and Vascular Medicine Faculty of Medicine, Brawijaya university.

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Presentation transcript:

Sodium and Renin Angiotension System Mohammad Saifur Rohman. MD. PhD. FIHA Dept. of cardiology and Vascular Medicine Faculty of Medicine, Brawijaya university

Sodium intake: Stone vs. Industrial Era

High Sodium intake: Cellular sodium excess

Sodium intake: Catecholamine release

Sodium-Calcium handling in SMC

Effect of low sodium diet

Sodium intake vs. Salt sensitive

High potassium intake

Effect of low potassium diet

Sodium handling and polymorphism

RAAS and sodium retention

Angiotensin II receptors

RAAS and Increased Arterial Pressure

The effect of brain Ang II

Multi organ effect of Ang II

High vs. low Renin

Angiotensin product

Effect of drugs on RAAS

Ang II and Vascular remodeling

Thank you

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