Carbohydrates Body’s preferred energy source Human brain uses it exclusively 2 categories simple complex Found in plants and dairy products
Carbohydrates Simple sugars monosaccharides disaccharides sweet Complex sugars polysaccharides not sweet
Glucose Fructose Galactose Found only as part of lactose Sucrose Lactose Maltose
Absorbed directly into blood stream without digestion Glucose (plant sugar) - 4 kcal/g from starch digestion or hydrolysis Other forms of CHO are converted into glucose - needs insulin for take up Dextrose- monohydrate of glucose used in IVF (3.4 kcal/g)
Fructose- fruit and honey Sweetest of all sugars Used almost exclusively in soft drinks Can be used in very small amounts to hide after taste in diet drinks
Galactose Appears in nature only as part of lactose “milk sugar” Changed to glucose for energy Reaction is reversible During lactation glucose reconverted to galactose for use in milk production
Compounds used in medications Cardiac glycosides - digitalis Steroids Antibiotics - streptomycin, erythromycin Deoxy sugars - DNA
Derivatives- sugar ETOH Sorbitol side effects: diarrhea, gas, abdominal discomfort Helps with dental caries Sorbitol occurs naturally in prunes, apple juice, etc. Liquid medications
Glucose Fructose Galactose Found only as part of lactose Sucrose Lactose Maltose
Maltose = glucose and glucose Plant sugar found in germinating cereal grains Used in some infant formulas and cereals Highly significant in human nutrition as intermediate product of starch digestion
Pairs of simple sugars linked together Sucrose = glucose and fructose Sugar beets, sugarcane, molasses, maple syrup Fructose converts to glucose in body 7-11% total kcal in American diet NO difference between honey and sugar
Lactose=glucose and galactose Principle CHO of milk Lactose intolerance common -no lactase or digestive enzyme in digestive system -can be transient after illness
Starch, glycogen, dextrin, dietary fiber Starch- hundreds of linked glucose units Amylopectin and amylose-ratios and structures differ ~80-85% amylopectin- insoluble ~15-20% amylose-soluble
Amlyopectin- thickening agent Amylose - slow even rate of digestion Amylase-digestive enzyme Cereal grains, legumes, potatoes Dextrin-intermediate product from breakdown of starch-makes maltose
Glycogen Stored energy Found in liver and muscle tissue Important link in energy metabolism Sustains normal blood sugars during fasting
Oligosaccharides Small portions of partially digested starches (3-10 monosaccharides) Infant formulas Special dietary formulas Sports drinks Faster and easier to digest
Dietary fiber Soluble and insoluble Celluloses, pectins, mucilages, gums, lignin Need grams/day Have laxative effect, soften stools Increase transit time, influence blood lipid levels
Dietary fiber Increase satiety Bulk helps with weight control, constipation, diverticulosis Undesirable effects- binds Fe ++, Ca ++, & Zn ++ Produce colon bacteria-volatile short chained fatty acids/GAS
Insoluble-Cellulose & Lignin Cellulose-not digestible has no nutrients produces bulk grains, fruits, vegetables Lignin is non-carbohydrate fiber binds bile acids and metals whole grain, strawberries, mature vegetables
Insoluble Soften stools Regulates bowel movements Increase fecal weight Increase transit time Reduce risks of diverticulosis, hemorrhoids, and appendicitis
Non-cellulose fiber Soluble-Absorbs water Slows gastric emptying Binds bile acids Adds some bulk Found in pectin gums mucilage
Carbohydrate Digestion Polysaccharides are broken down to Disaccharides are broken down to Monosacharides which are absorbed through intestinal mucosa and transported to the liver
Carbohydrate Metabolism In the liver: Fructose and Galactose converted to Glucose Blood sugars rise Insulin secreted Insulin moves glucose out to bloodstream and into cells
Carbohydrate Metabolism Muscle cells convert glucose to glycogen if storage CHO is needed. IF energy needed, glucose is burned in cells. Glucose not needed for energy or glycogen is used to make DNA, RNA, or converted to fatty acids and stored as triglycerides.
Carbohydrate Function Provides energy-especially to brain, nervous system, used by muscles 4 kcalories per gram Spares protein Prevents ketosis Quickly digested-principle site is small intestine
Glycogen Immediate fuel for muscle actions kcal on board 2/3 stored in muscle/ 1/3 in liver g of water stored with every gram of glycogen
Glycogen Minimum of 100g CHO/ day to prime citric acid cycle to prevent keto-acidosis to prevent excessive tissue protein breakdown Symptoms from lack of CHO : fatigue, dehydration
Healthy Diet CHO 50-60% of daily diet 10% of this amount should be sweets Fiber intake grams/day CHO alone does not cause obesity remember fat and activity levels
Chronic Diseases Diabetes-Type 2 related to body fatness 95% of DM are Type 2 Heart Disease-fat not sugars Sugar behavior-unproven
Nutrients in 100 Kcalories Food ProteinCalcium Sugar (2T) 0 g trace Cola (1 C) 0 g 6 mg Milk (1 c) 8 g300 mg Bread ( 1 slice) 3 g 48 mg Pinto Beans (1/2 c) 7 g 41 mg
Sugar Alcohols Used in chewing gums 2-3 kcal per gram Examples: Sorbitol Isomalt Xylitol
Artificial Sweeteners Saccharin-pros and cons Aspartame-Equal Acesulfame K- Sunette & Sweet One Sucralose-Splenda Use as replacement, not addition, if used for weight control
Glycemic Response Effect of a particular food on blood glucose reduced to a number Factors: Amount of fat and fiber Method of preparation Amount eaten Use for fine tuning meal planning with DM patients and athletes
GI Food Pyramid Refined Grains Potatoes Sweets Unrefined Grains Pasta Dairy Lean Protein Nuts Legumes Fruits Vegetables
Fat & Energy Used to meet 50% of energy needs Most cells can utilize fat for energy Not brain cells or nerves Fat cannot be converted to glucose
Ketosis? Ketone bodies Acidic, fat related compounds formed from incomplete breakdown of fat when no carbohydrate is available.
Protein and Energy Protein used for energy when glycogen depleted Body starts to auto-digest CHO has protein sparing effect