An Introduction to the Human Body Lecture Outline Chapter 1 An Introduction to the Human Body Lecture Outline

INTRODUCTION The purpose of the chapter is: Introduce anatomy and physiology as specific disciplines. Consider how living things are organized. Reveal shared properties of all living things. Principles of Human Anatomy and Physiology, 11e

Chapter 1: An Introduction to the Human Body Anatomy science of structure relationships revealed by dissection (cutting apart) imaging techniques Physiology science of body functions normal adult physiology is studied in this text some genetic variations are described Principles of Human Anatomy and Physiology, 11e

Levels of Organization Chemical Cellular Tissue Organs System Level Organismic Level Principles of Human Anatomy and Physiology, 11e

LEVELS OF ORGANIZATION (Figure 1.1). The Chemical Level atoms, the smallest units of matter that participate in chemical reactions, and molecules, two or more atoms joined together. Cells the basic structural and functional units of an organism. Tissues groups of similarly specialized cells and the substances surrounding them that usually arise from a common ancestor and perform certain special functions. Principles of Human Anatomy and Physiology, 11e

LEVELS OF ORGANIZATION Organs structures of definite form that are composed of two or more different tissues and have specific functions. Systems related organs that have a common function. The Human Organism a collection of structurally and functionally integrated systems; any living individual. Principles of Human Anatomy and Physiology, 11e

Clinical Application Three noninvasive techniques: used to assess certain aspects of body structure and function. Palpation The examiner feels body surfaces with the hands; an example would be pulse and heart rate determination. Auscultation The examiner listens to body sounds to evaluate the functioning of certain organs, as in listening to the lungs or heart. Percussion The examiner taps on the body surface with the fingertips and listens to the resulting echo. Principles of Human Anatomy and Physiology, 11e

CHARACTERISTICS of the LIVING HUMAN ORGANISM All living things have certain characteristics that distinguish them from nonliving things. Metabolism Responsiveness Movement Growth Differentiation Reproduction Principles of Human Anatomy and Physiology, 11e

Basic Life Processes Metabolism is the sum of all chemical processes that occur in the body, including catabolism and anabolism. Responsiveness is the ability to detect and respond to changes in the external or internal environment. Movement includes motion of the whole body, individual organs, single cells, or even organelles inside cells. Principles of Human Anatomy and Physiology, 11e

Basic Life Processes Growth refers to an increase in size and complexity, due to an increase in the number of cells, size of cells, or both. Differentiation is the change in a cell from an unspecialized state to a specialized state. Reproduction refers either to the formation of new cells for growth, repair, or replacement, or the production of a new individual. Principles of Human Anatomy and Physiology, 11e

Body Fluids Fluid inside body cells is called intracellular fluid. Fluid outside body cells is called extracellular fluid (ECF) and are either: Interstitial fluid- Fluid between the cells. Plasma-The nonliving fluid component of blood. Principles of Human Anatomy and Physiology, 11e

HOMEOSTASIS Homeostasis is a condition of equilibrium in the body’s internal environment produced by the ceaseless interplay of all the body’s regulatory processes. Principles of Human Anatomy and Physiology, 11e

CONTROL OF HOMEOSTASIS Homeostatic imbalances occur because of disruptions from the external or internal environments. Homeostasis is regulated by the nervous system and endocrine system, acting together or independently. The nervous system detects changes by sending nerve impulses. The endocrine system regulates homeostasis by secreting hormones. Principles of Human Anatomy and Physiology, 11e

Feedback Systems A feedback system consists of three basic components. A receptor monitors changes in a controlled condition and sends input in the form of nerve impulses or chemical signals to a control center. The control center sets the range of values within which a controlled condition should be maintained, evaluates the input it receives from the receptors, and generates output commands when they are needed. An effector is a body structure that receives output from the control center and produces a response or effect that changes the controlled condition. Principles of Human Anatomy and Physiology, 11e

Components of Feedback Loop Principles of Human Anatomy and Physiology, 11e

Feedback Systems If a response reverses the original stimulus, the system is a negative feedback system. If a response enhances the original stimulus, the system is a positive feedback system. Principles of Human Anatomy and Physiology, 11e

Negative Feedback Systems A negative feedback system reverses a change in a controlled condition. Homeostasis of Blood Pressure (BP): Negative Feedback The activity of the effector produces a result, a drop in blood pressure, that opposes the stimulus, an increase in blood pressure. Principles of Human Anatomy and Physiology, 11e

Positive Feedback System Normal childbirth provides a good example of a positive feedback system The positive feedback system reinforces a change in a controlled condition. Principles of Human Anatomy and Physiology, 11e

Homeostatic Imbalances Disorder is a general term for any derangement of abnormality of function. Disease is a more specific term for an illness characterized by a recognizable set of signs and symptoms. A local disease is one that affects one part or a limited region of the body. A systemic disease affects either the entire body or several parts. Principles of Human Anatomy and Physiology, 11e

Aging and Homeostasis Aging is characterized by a progressive decline in the body’s responses to restore homeostasis These changes are apparent in all body systems. crinkled skin, gray hair, loss of bone mass, … Principles of Human Anatomy and Physiology, 11e

BASIC ANATOMICAL TERMINOLOGY Anatomical position Regions of the body Anatomical planes, sections and directional terms Principles of Human Anatomy and Physiology, 11e

Anatomical Position The anatomical position is a standardized method of observing or imaging the body that allows precise and consistent anatomical references. When in the anatomical position, the subject is: standing upright facing the observer, head level eyes facing forward feet flat on the floor arms at the sides palms turned forward (ventral)

Reclining Position If the body is lying face down, it is in the prone position. If the body is lying face up, it is in the supine position. Principles of Human Anatomy and Physiology, 11e

Clinical terminology is based on a Greek or Latin root word. Common Regional Names cranial (skull), thoracic (chest), brachial (arm), patellar (knee), cephalic (head), and gluteal (buttock) Clinical terminology is based on a Greek or Latin root word. Principles of Human Anatomy and Physiology, 11e

Superior or Inferior Superior towards the head The eyes are superior to the mouth. Inferior away from the head The stomach is inferior to the heart. Principles of Human Anatomy and Physiology, 11e

Dorsal or Ventral Dorsal or Posterior at the back of the body The brain is posterior to the forehead. Ventral or Anterior at the front of the body The sternum is anterior to the heart. Principles of Human Anatomy and Physiology, 11e

Medial or Lateral Medial nearer to the midline of the body The heart lies medial to the lungs. Lateral farther from the midline of the body The thumb is on the lateral side of the hand. Principles of Human Anatomy and Physiology, 11e

Proximal or Distal Proximal nearer to the attachment of the limb to the trunk The knee is proximal to the ankle. Distal farther from the attachment of the limb to the trunk The wrist is distal to the elbow. Principles of Human Anatomy and Physiology, 11e

More terms Intermediate: between two structures Ipsilateral: On the same side of the body Contralateral: on opposite sides of the body Superficial: towards the body surface Deep: Away from the surface of the body Principles of Human Anatomy and Physiology, 11e

Planes Planes are imaginary flat surfaces that are used to divide the body or organs into definite areas Principles of Human Anatomy and Physiology, 11e

Sagittal Planes Sagittal plane divides the body or an organ into left and right sides Midsagittal plane produces equal halves Parasagittal plane produces unequal halves Principles of Human Anatomy and Physiology, 11e

Other Planes and Sections Frontal or coronal plane (vertical) divides the body or an organ into front (anterior) and back (posterior) portions Transverse(cross-sectional) or horizontal plane divides the body or an organ into upper (superior) or lower (inferior) portions Oblique plane (diagonal) some combination of 2 other planes Principles of Human Anatomy and Physiology, 11e

Body Cavities Body cavities are spaces within the body that help protect, separate, and support internal organs. Principles of Human Anatomy and Physiology, 11e

Dorsal Body Cavity Near dorsal surface of body 2 subdivisions cranial cavity holds the brain formed by skull vertebral or spinal canal contains the spinal cord formed by vertebral column Principles of Human Anatomy and Physiology, 11e

Ventral Body Cavity Near ventral surface of body 2 subdivisions thoracic cavity above diaphragm: heart and lungs abdominopelvic cavity below diaphragm: the stomach, spleen, pancreas, liver, gallbladder, small intestine, and most of the large intestine; the urinary bladder, portions of the large intestine and internal female and male reproductive structures. Principles of Human Anatomy and Physiology, 11e

Membranes The serous membranes include the pleura, pericardium and peritoneum The pleural membrane surrounds the lungs (ventral cavity) The pericardium membrane covers the surface of the heart (ventral cavity) The peritoneum is the serous membrane of the abdominal cavity, it lines the abdominal wall Principles of Human Anatomy and Physiology, 11e

Clinical Application: Autopsy An autopsy is a postmortem examination of the body and dissection of the internal organs to confirm or determine the cause of death. Principles of Human Anatomy and Physiology, 11e

MEDICAL IMAGING Medical imaging techniques allow physicians to peer inside the body to provide clues to abnormal anatomy and deviations from normal physiology in order to help diagnose disease.

Conventional Radiography / XRays A single burst of Xrays Produces 2-D image on film Poor resolution of soft tissues Major use is osteology Principles of Human Anatomy and Physiology, 11e

Computed Tomography (CT Scan) Moving x-ray beam Image produced on a video monitor of a cross-section through body Computer generated image reveals more soft tissue detail kidney & gallstones Multiple scans used to build 3D views Principles of Human Anatomy and Physiology, 11e

Digital Subtraction Angiography(DSA) Radiopaque material injected into blood vessels Before and after images compared with a computer program Image of blood vessel is shown on a monitor Principles of Human Anatomy and Physiology, 11e

Ultrasound (US) High-frequency sound waves emitted by hand-held device Safe, noninvasive & painless Image or sonogram is displayed on video monitor Used for fetal ultrasound and examination of pelvic & abdominal organs, heart and blood flow through blood vessels Principles of Human Anatomy and Physiology, 11e

Magnetic Resonance Imaging (MRI) Body exposed to high-energy magnetic field Protons align themselves relative to magnetic field Pulse of radiowaves used to generate an image on video monitor Can not use on patient with metal in their body Reveals fine detail within soft tissues Principles of Human Anatomy and Physiology, 11e

Positron Emission Tomography(PET) Substance that emits positively charged particles is injected into body Collision with negatively charged electrons in tissues releases gamma rays Camera detects gamma rays & computer generates image displayed on monitor Principles of Human Anatomy and Physiology, 11e