New Directions for Mental Health and Drug Abuse Effectiveness and Dissemination Trial Research and Methodology C Hendricks Brown, USF Nick Ialongo, JHU Irwin Sandler, ASU John Reid, OSLC

Bloomberg School of Public Health at Johns Hopkins 2 Prevention Science & Methodology Group Supported by NIMH and NIDA USF – C. Hendricks Brown, Principal Investigator Dagne, Co-Principal Investigator, Brinales, Wang, Stockwell, Greenbaum, Toyinbo, Downes UCLA– Bengt Muthén, Co-Principal Investigator, Nylund American Institutes for Research– Kellam, Poduska Hopkins– Ialongo, Bandeen-Roche U Maryland, Petras Oregon Social Learning Center– Reid, Chamberlain, Smith Stanford -- Jo George Washington– Howe Arizona State U -- MacKinnon UC San Diego – Tsuang, Landsverk, Hurlburt, Aarons UC Davis – Masyn U Colorado -- Henry U Miami – Szapocznik, Pantin, Henderson, Schwartz Florida International U -- Feaster, Prado U Rochester – Wyman, Cross, Peña U Washington – Brown Towson University – VanFossen U Illinois Urbana-Champaign – Klein U Mass–Indurkhya SUNY Upstate Medical University -- Faraone Hvidovre Hospital, Copenhagen – Larsen U Texas, San Antonio -- Wang

Bloomberg School of Public Health at Johns Hopkins 3 Methodology for Mental Health & Drug Abuse Prevention and Early Intervention Specific Aims 1.Develop new statistical designs and analytic methods for examining intervention impact across person, environment, and developmental course. 2.Develop new statistical designs and analytic methods for examining preventive and early intervention impact on low baserate disorders. 3.Develop new designs and analytic methods for examining impact as interventions are implemented community-wide. Inclusion of Genetics in Mental Health and Drug Abuse Prevention and Early Intervention.

Bloomberg School of Public Health at Johns Hopkins 4 Methodology for Mental Health & Drug Abuse Prevention and Early Intervention Advisory Board John Reid Oregon Social Learning Center & Center for Research to Practice Ming Tsuang UC San Diego Steven Faraone, SUNY Upstate Medical University Robert Gibbons, U Illinois, Chicago Circle Co-PI’s C Hendricks Brown, USF Bengt Muthén, UCLA Getachew Dagne, USF UCLA Bengt Muthén, Karen Nylund American Institutes for Research Sheppard Kellam, Jeanne Poduska George Washington University George Howe University of Miami José Szapocznik, Hilda Pantin Arizona State University David MacKinnon

Bloomberg School of Public Health at Johns Hopkins 5 Where Does Prevention Methodolgy Fit?