What’s new in Cochrane? Carol Lefebvre MSc HonFCLIP Senior Information Specialist UK Cochrane Centre Oxford, UK MLA, Minneapolis, 16 May 2011

Presentation overview The Cochrane Library: an overview CDSR and CENTRAL (the clinical trials register in CLIB) How to access The Cochrane Library? What else is new in The Cochrane Collaboration? ‘Cochrane for Librarians’ The Cochrane library: Training and Support Summary Questions and comments

Who uses The Cochrane Library? Who has access to The Cochrane Library ? Who has used The Cochrane Library? Who uses it regularly (weekly)?

Use of The Cochrane Library Usage estimates for 2009: a search of CLIB every 1 second an abstract viewed every 2 seconds a full text review downloaded every 3 seconds (across all web platforms, including Wiley InterScience, cochrane.org, La Bibliotheca Cochrane Plus, Bireme, OVID and EBSCO)

The Cochrane Library: an overview Cochrane Database of Systematic Reviews –(CDSR; Cochrane Reviews) 4,621 Database of Abstracts of Reviews of Effects –(DARE; Other Reviews) 14,602 Cochrane Central Register of Controlled Trials –(CENTRAL; Clinical Trials) 645,086 Cochrane Methodology Register –(CMR; Methods Studies) 14,604 Health Technology Assessment Database –(HTA; Technology Assessments) 9,965 NHS Economic Evaluation Database –(NHSEED; Economic Evaluations) 29,570 About The Cochrane Collaboration (Cochrane Groups) 81 (15 May 2011)

Who produces it? The Cochrane Collaboration 52 clinically-focussed Review Groups e.g. HIV/AIDS, prostate urologic cancers 14 national/regional Centres e.g. UKCC, USCC 12 Fields e.g. Complementary Medicine 15 Methods Groups e.g. Information Retrieval

Who publishes it? Wiley-Blackwell –on behalf of The Cochrane Collaboration –under contract – open competitive tender

Cochrane Database of Systematic Reviews (CDSR) 4,621 full reviews – of the effects of interventions/DTA/overviews 2,020 protocols – reviews in preparation (CLIB – 15 May 2011)

What is special about CDSR? up-to-date systematic reviews of existing evidence higher quality than other systematic reviews (but …) reviews updated with new studies / improved methods amended / updated from comments and criticisms –pre- and post-publication

What is new about CDSR? From January 2010 CDSR is updated monthly online (not quarterly) (The DVD continues to be published quarterly) Other databases continue to be updated quarterly except About The Cochrane Collaboration / “Cochrane Groups” (monthly)

What is new about CDSR? Diagnostic test accuracy reviews (4) Diagnostic Test Accuracy Working Group, DTA Regional Support Units and DTA Editorial Team web site and links to DTA reviews –

What is new about CDSR? Overviews of reviews (10) e.g. Biologics for rheumatoid arthritis: an overview of Cochrane reviews Consumer-oriented interventions for evidence-based prescribing and medicine use: an overview of Cochrane reviews Open, small-incision, or laparoscopic cholecystectomy for patients with symptomatic cholecystolithiasis. An overview of Cochrane Hepato- Biliary Group reviews

What is new about CDSR? Special Collections e.g.World asthma day (3 May ) International Clinical Trials Day (20 May) World no tobacco day (31 May)

What is new about CDSR? The Cochrane Collaboration’s Evidence Aid project: established Dec 2004 (Indian Ocean tsunami) provides reliable, up-to-date evidence from Cochrane Reviews and other systematic reviews interventions for natural disasters / major healthcare emergencies which interventions work / don’t work / need more research / might be harmful provides information to agencies planning for / responding to disasters

What is new about CDSR? Evidence Aid (cont): Wiley-Blackwell / The Cochrane Collaboration / Evidence Aid opened free, one-click access to the whole contents of The Cochrane Library to everyone in Japan on the day of the earthquake / tsunami (11 March 2011) Information translated into Japanese

What is new about CDSR? Impact factor for CDSR for 2009 = ranked 11th in the ‘Medicine, General & Internal’ category out of the 132 journals included in the ISI Medicine, General and Internal journal list (previously 12 th )

CENTRAL – clinical trials register in CLIB c. 650,000 reports of RCTs and other controlled trials –350,000 from MEDLINE (all records indexed as RCT or CCT in PT in humans) –100,000 additional reports of trials from searching EMBASE –200,000 reports of trials from handsearching journals / conference abstracts (CLIB – 15 May 2011)

What is special about CENTRAL? unique! best single source of reports of randomized controlled trials ‘trials on a plate’

What is new about CENTRAL? In October 2009 Metaxis awarded contract to build a new Cochrane Register of Studies (CRS) – to feed into CENTRAL Due for release internally late 2011 CRS will be study-based and reference-based – as will CENTRAL

How to access The Cochrane Library ? –FREE access to CDSR titles, abstracts and plain language summaries pay-to-view option for full record for non- subscribers –free access to CENTRAL (titles only) –free access to the titles of records from other database FULL access to all records for subscribers through: Wiley-Blackwell, EBSCO and Ovid

How to access The Cochrane Library ? Types of subscription national provisions (population-wide) many countries – but not (yet) the US! regional provisions (population-wide) e.g. some Canadian provinces and Wyoming professional provisions e.g. through professional associations Evidence Aid / HINARI / INASP

What else is new in The Cochrane Collaboration? Editor-in-Chief, Dr David Tovey, appointed late 2008 Focus on ensuring quality in Cochrane Reviews Updating of Cochrane Reviews Web programme a priority CLIB / cochrane.org re-launched early 2010 Information Specialist appointed to the CEU in

What else is new in The Cochrane Collaboration? Improving quality in Cochrane Reviews –MECIR (Methodological Expectations in Cochrane Intervention Reviews) –Expectations / standards / recommendations –Mandatory / highly desirable / good practice –MECIR Searching for Studies WG Searches conducted by an Info Prof? MEDLINE/EMBASE/CENTRAL/SR? Core search strategy in every Protocol? Search strategies peer reviewed by an Info Prof?

What else is new in The Cochrane Collaboration? ‘Cochrane Response’ – brokerage between commissioners of reviews and Cochrane Review Groups ‘Cochrane PICOs’ – concise, readable, digestible and actionable summaries of reviews Podcasts - since Jan 2008

What else is new in The Cochrane Collaboration? RSS feeds from CLIB: e.g. editorials, special collections and highlights of new and updated Cochrane Reviews RSS feeds from cochrane.org: e.g. podcasts, workshops and news items Facebook Twitter

What else is new in The Cochrane Collaboration? Cochrane Journal Club: based on a recent Cochrane review (monthly) relevant background information and related resources podcasts by the authors explaining the key points of the review discussion questions to help explore the review methods and findings in more detail downloadable PowerPoint slides containing key figures and tables focuses on a review of special interest, such as a review that will change practice or one that employs a new statistical method 19 issues currently available

What else is new in The Cochrane Collaboration? Jan accepted as a ‘Non-Governmental Organization in Official Relations with the WHO’ establishes a partnership with formalized communication between our two organisations awarded a seat at the World Health Assembly, allowing us to provide input on WHO health resolutions.

‘Cochrane for Librarians’ The Cochrane Handbook for Systematic Reviews of Interventions – Chapter 6 – Searching for Studies –lists of sources – including databases, trials registers etc –search hints and tips –RCT filters for MEDLINE useful when supporting systematic reviews etc essential when supporting Cochrane Reviews!

‘Cochrane for Librarians’ Where to find the Reviewers’ Handbook Lefebvre C, Manheimer E, Glanville J, on behalf of the Cochrane Information Retrieval Methods Group. Chapter 6: Searching for studies. In: Higgins JPT, Green S, editors. Cochrane Handbook for Systematic Reviews of Interventions. Version [updated March 2011]. The Cochrane Collaboration, Available from:

‘Cochrane for Librarians’ The Cochrane Information Retrieval Methods Group The Cochrane Library Users’ Group Have your say!

‘Cochrane for Librarians’ Next Cochrane Colloquium Madrid, Spain October 2011 Presentations from past Colloquia and Cochrane regional meetings available as videos, slidecasts, podcasts etc e.g. audio synced to PowerPoint slides e.g. video synced to PowerPoint slides cochrane-colloquia-and-meetings

The Cochrane Library: training and support CLIB Search Manual ml User Guide and Quick Reference Guide Online self-paced tutorials Database help files (CENTRAL and Cochrane Methodology Register) WebEx training - Instructor-led tutorials

Summary Focus on improving quality of Cochrane Reviews including the quality of the searches Focus on improving access – free at the point of use Focus on improving interactivity Visit Wiley - Booth # 318

Questions and comments