Boston University Kenneth Lutchen Professor and Chair Workshop on BME Teaching of Innovation, Design & Entrepreneurship BOSTON U N I V E R S I T YU N I V E R S I T Y

The BU-BME Senior Project Program u Course 1Communicate Realistic u Course 1: How to Approach, Perform, Manage and Communicate Independent Technical Projects, most in Realistic “Team”. u Course 2 u Course 2: Introduce Students to Best Practices in Design, Development, Marketing and Entrepreneurship in BME Industry u Engages all Full-time Faculty, Industrial Advisory Board, School Management, and use of Outside Hospitals, Laboratories, Companies as additional project mentors. u Faculty Provide Technical Guidance and Mentoring u Builds Repertoire of Technical Communication Skills –how skills complement scientific progress and discovery Continuous u Detailed Technical/Scientific (Individual) Accountability is Enforced through “Continuous” Technical Communication u Holy Grail of Accountability is Final Conference –subliminal competition among students (and faculty) BOSTON U N I V E R S I T YU N I V E R S I T Y

Course 1: Biomedical Engineering Senior Projects. u Semester I (2 credits) –Introduction –Approach to Independent Research –Proposal Writing –Statistical Analysis –Oral Presentation Techniques (proposal) »By good & bad example u Semester II (4 credits u Semester II (4 credits) –Progress Report Writing –Scientific Ethics –Abstract Writing –Final Report Writing –Oral Presentation Techniques (final report) BOSTON U N I V E R S I T YU N I V E R S I T Y

Course 2: Design, Development, Marketing, and Entrepreneurship in Biomedical Engineering u Transition from Engineer to Product Developer –Art Rosenthal, Chief Scientific Officer, Boston Scientific Co. u Medical Device Development Art Coury, Vice President, Genzyme Corp. u Marketing Driven Strategies and Marketing –Peter Russo, Director Entrep. & Management Institute, BU SMG u Intellectual Property and Innovation in BME –Steve Girouard, Manager Heart Group, Guidant Corp. u Quality Control and Reliability in Hardware and Software Medical Device Industry –David Jones, Director Quality Control, Phillips Medical Systems u Clinical Regulatory Issues in BME –Robert Kung, Vice President, Abiomed u Entrepreneurship in Biomedical Engineering –Peter Russo, Director Entrep. & Management Institute, BU SMG –Panel: Case Studies (Three BME faculty with Start Up Companies)

Novel & Effective Methods: Innovation & Entrepreneurship u Proposals (must defend what is novel) u Senior Conference (public presentation motivates innovation) u Lectures on process of innovations –Deliverables (patent search and analysis) u Lectures on Entrepreneurship –Deliverable (mini-business plan) u Panel Discussion from Faculty with Concrete Experience in Innovation and Entrepreneurship BOSTON U N I V E R S I T YU N I V E R S I T Y

How do you measure outcomes? u Editing Capabilities u Proposals (Science-type Format) u Progress Reports u Outcomes Related to Product Design and Innovation: –Recasting of Project in Terms of Functional vs. Performance Specifications –Casting Project via a projected product and addressing Intellectual Property, Market Analysis, and Business Plan for Potential Product u Final Report u Final “Public” Conference BOSTON U N I V E R S I T YU N I V E R S I T Y

Senior Project Conference “The Capstone within a Capstone ” BOSTON U N I V E R S I T YU N I V E R S I T Y

u Formal Technical Conference: Oral Only u Attended by: u All BME Faculty u All BME Seniors u Many UG & Grads & Alumni u Numerous BME Companies & Laboratories (> 150 guests/yr)

18th Annual Biomedical Engineering Senior Project Conference 7:50Opening Remarks 8:00Session 1: Cell and Tissue Engineering & Micro BioSystems 9:35Break 10:00Session 2: Patient Monitoring, Bioinstrumentation & Biomedical Optics 11:50Lunch 12:40Session 3A: Genomic Engineering Session 3B: Neuromuscular and Neurofeedback Enginereing 1:55Break 2:05Session 4: Auditory and Neuro Bioengineering 3:25Break 3:45Session 5: Biomedical Imaging & Cell-Tissue-Organ Biomechanics 5:35Closing Remarks BOSTON U N I V E R S I T YU N I V E R S I T Y

Examples and Range of Topics for Senior Capstone Projects u Nanoporous Inorganic Biocapsules for Cellular Immunoisolation and Controlled Drug Delivery u Fabrication of Vascular Network In Vitro u Optical Measurement of Drug Diffusion into Tissue u Design and Implementation of a System for Real-Time Experimental Control of Auditory Stimuli u Using a Genetic Toggle Switch and Bacteriophage to Control Biofilm Formation u Use of Foot Pressure Related Feedback to Improve Balance Control u Modeling Intracellular Signaling Pathways u Perfusion MRI of Brain Tumors in a Mouse Model of Arterial Spin Labeling u Induction of a Joint Structure by Controlled Stimulation During Fracture Healing u Quantifying Lung Compliance in Acute Respiratory Distress via High Resolution Computer Tomography BOSTON U N I V E R S I T YU N I V E R S I T Y