Fungal infections Dr.Majdy Naim.

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Presentation transcript:

Fungal infections Dr.Majdy Naim

Majdy Naim Fungal infections of the skin Superficial fungal infections ( affecting the skin primarily ) Deep fungal infections ( starting in the internal organs and involve the skin secondarily ) Majdy Naim Fungal infections of the skin

Superficial fungal infections Dermatophytes Epidermophyton Trichophyton Microsporum Yeasts Candida Malassezia furfur Majdy Naim Fungal infections of the skin

Classification of dermatophytic infections Tinea capitis Tinea corporis ( Tinea circinata ) Tinea faceie Tinea barbae Tinea cruris Tinea pedis Onychomycosis Majdy Naim Fungal infections of the skin

Majdy Naim Fungal infections of the skin Tinea capitis Majdy Naim Fungal infections of the skin

Majdy Naim Fungal infections of the skin Tinea capitis In general 3 types Scaly Kerion Black-dot Majdy Naim Fungal infections of the skin

Majdy Naim Fungal infections of the skin Scaly ringworm In school children Single or multiple round patches with fine grayisch-white scales The hairs in this area become loos and break off leaving stumps about 3 mm long These stumps are easily pulled out Mainly due to Trichophyton violaceum and Microsporum canis Majdy Naim Fungal infections of the skin

Majdy Naim Fungal infections of the skin Kerion The patches form follicular pustules, or boggy swelling like an abscess Causes fall out of the hair May end by scaring and permanent baldness Usually due to fungi of an animal origin ( mainly Trichophyton verrucosum and microsporum canis ) Majdy Naim Fungal infections of the skin

Majdy Naim Fungal infections of the skin Kerion Majdy Naim Fungal infections of the skin Dr. Majdy Naim

Kerion ( after 4months therapy) Dr. Majdy Naim Majdy Naim Fungal infections of the skin

Kerion differs from an abscess in: Less painfull Absence of general symptoms Contains no pus Kerion should not be incised Majdy Naim Fungal infections of the skin

Majdy Naim Fungal infections of the skin Black-dot The hairs do not form stumps but break of nesr the surface of the follicles May show slight scaling Caused by Trichophyton violaceum Majdy Naim Fungal infections of the skin

Tinea capitis (mode of infection) Direct Man to Man Animal Indirect Use of patient‘s fomites Friseur Majdy Naim Fungal infections of the skin

Diagnosis of tinea capitis Clinical examination Woods Light Microskopic examination ( KOH) Culture (Sabourauds agar medium) Majdy Naim Fungal infections of the skin

Treatment of tinea capitis Systemic therapy Essential Griseofulvin for 8 weeks Terbenafen (Lamisil) 6 weeks Topical therapy Alone useless Antifugal ceams Antifugal shampoo Majdy Naim Fungal infections of the skin

Majdy Naim Fungal infections of the skin Tinea corporis Majdy Naim Fungal infections of the skin

Majdy Naim Fungal infections of the skin Tinea corporis Seen in any age, but children are most susceptible Caused by almost all species of trichophyta and microspora Lesions are annular with central healing and active edge They are single or multiple, and can be itchy Majdy Naim Fungal infections of the skin

Majdy Naim Fungal infections of the skin Treatment Topical antifungul By localized moderate cases Systemic antifungal By extensive or resistant cases Majdy Naim Fungal infections of the skin

Majdy Naim Fungal infections of the skin Tinea Facei Face except moustache and beard area in adult male Any part of the face in children May be steroid modified Majdy Naim Fungal infections of the skin

Majdy Naim Fungal infections of the skin Tinea barbae Deep fungus infection Adult men Mostly by animal farmers Majdy Naim Fungal infections of the skin

Majdy Naim Fungal infections of the skin Tinea cruris More frequently during the summer months most cases caused by Epidermophyton floccosum and Trichphyton rubrum Affect the upper and inner surface of the thighs Often extend into the gluteal folds and onto the buttocks Itching occurs especially in acute types Majdy Naim Fungal infections of the skin

Majdy Naim Fungal infections of the skin Tinea Cruris Acute Subacute Chronic Majdy Naim Fungal infections of the skin

Majdy Naim Fungal infections of the skin Tinea Cruris Majdy Naim Fungal infections of the skin

Tinea cruris Differential diagnosis Simple intertrigo Seborrheic dermatitis Candidiasis Erythrasma Flexural psoriasis Contact dermatitis Majdy Naim Fungal infections of the skin

Majdy Naim Fungal infections of the skin Treatment Topical antifungul By mild to moderate cases Systemic antifungal By extensive or resistant cases Majdy Naim Fungal infections of the skin

Majdy Naim Fungal infections of the skin Tinea pedis Most common fungus infection In general a disease of adult life Often in summer months The mode of infection is usually by using infected socks, shoes or other towels, also from wet floor-boards Caused mainly Trichophyton interdigitale, T. rubrum Epidermophyton floccosum Majdy Naim Fungal infections of the skin

Tinea pedis (Athletes foot) Majdy Naim Fungal infections of the skin

Majdy Naim Fungal infections of the skin Tinea pedis Majdy Naim Fungal infections of the skin

Dermatophyte infections Keratinised epithelium: Tinea corporis Tinea faciale Tinea cruris Tinea manus Tinea pedis Nails: Tinea unguium (Onychomycosis ) Hairs: Tinea capitis Tinea barbae Majdy Naim Fungal infections of the skin

Majdy Naim Fungal infections of the skin Onychomycosis Majdy Naim Fungal infections of the skin

Majdy Naim Fungal infections of the skin Onychomycosis Nail may show discoloration, thickining, cracking, subungular hyperkeratosis or onycholysis One or more nails are involved May be associated with tinea pedis Majdy Naim Fungal infections of the skin

Majdy Naim Fungal infections of the skin Tinea manuum Majdy Naim Fungal infections of the skin

Majdy Naim Fungal infections of the skin Yeasts infection Candidiasis Tinea versicolor Majdy Naim Fungal infections of the skin

Majdy Naim Fungal infections of the skin Candidiasis 80 % Candida albicans Majdy Naim Fungal infections of the skin

Majdy Naim Fungal infections of the skin Oral candidiasis Thrush Angular cheilitis Majdy Naim Fungal infections of the skin

Majdy Naim Fungal infections of the skin Candidiasis Majdy Naim Fungal infections of the skin

Majdy Naim Fungal infections of the skin Candidiasis Oral candidiasis Thush,Angular stomatitis,Candidal glossitis,Black hairy tongue Intertriginous candidiasis Genital candidiasis Vulvovaginal candidiasis, Candidial balanoposthitis Candidal paronychia Napkin candidiasis Majdy Naim Fungal infections of the skin

Majdy Naim Fungal infections of the skin Predisposing factors Trauma Friction Moisture and sweating Drugs Conditions associated with low resistance Majdy Naim Fungal infections of the skin

Pityriasis versicolor Majdy Naim Fungal infections of the skin

Pityriasis versicolor Very common superfacial mycotic infection Caused by malassezia furfur Commonly affects young adults Climatic factors and familial predisposition appear to be important Majdy Naim Fungal infections of the skin

Majdy Naim Fungal infections of the skin Treatment Short application of selenium sulfate (10-15 min) for 2 weeks Topical antifungals as shampoo or cream Systemic antifungals Majdy Naim Fungal infections of the skin