D.B. Sanders, MD UW-Madison Parent Webinar PULMONARY EXACERBATION NUTS AND BOLTS.

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D.B. Sanders, MD UW-Madison Parent Webinar PULMONARY EXACERBATION NUTS AND BOLTS

 An acute worsening of signs and symptoms  Cough, increased sputum, decreased energy, decreased appetite, weight loss  Can include coughing up blood, shortness of breath, chest pain  Usually accompanied by an acute decrease in lung function (usually, FEV 1 )  35-40% of patients with CF require IV antibiotics each year  Many more require oral or inhaled antibiotics DEFINITION/EPIDEMIOLOGY

 Anything that disrupts the bacteria that can be found in the lungs of people with CF:  New bacteria (Pseudomonas aeruginosa)  Old bacteria, new growth, or new virulence  Viral infections (influenza)  Not taking medications regularly  Other: pollution, allergies, reflux (heartburn), ABPA WHAT CAUSES A PULMONARY EXACERBATION?

 You don’t feel good  Missed work, missed school, missed activities  May require hospitalization  May lead to more decline in lung function  ~25% of patients don’t immediately recover all of their lung function after they are hospitalized for an exacerbation WHY ARE EXACERBATIONS IMPORTANT?

 If you are having symptoms of an exacerbation:  Increase chest PT to 3-4 times per day  Make sure you are taking all of your medications  Call us if symptoms are really bad, or if they’re not getting better after 4-5 days WHAT TO DO?

 We may prescribe oral or inhaled antibiotics over the phone  We may ask you to come to clinic for a visit  We may decide to admit you to the hospital  In the hospital:  We use IV antibiotics (usually 2)  We give chest PT 4 times per day  We make sure to increase nutrition  We try to make sure you get rest WHAT ARE OUR OPTIONS?

 Take your medications and do your chest PT  Maintain your weight  Get the flu vaccine every year  Avoid people with colds/wash your hands  Let us know early HOW CAN YOU PREVENT AN EXACERBATION?