The Molecular Basis of Inheritance Chapter 16 The Molecular Basis of Inheritance Copyright © 2008 Pearson Education, Inc., publishing as Pearson Benjamin Cummings.

The DNA Model What kind of evidence about the structure of DNA came from each of the following branches of science? physics chemistry biology Copyright © 2008 Pearson Education, Inc., publishing as Pearson Benjamin Cummings.

The Genetic Material If the result of the Hershey and Chase experiment had been that radioactive sulfur (35S) was found inside the cells instead of radioactive phosphorous (32P), what could have been concluded? Copyright © 2008 Pearson Education, Inc., publishing as Pearson Benjamin Cummings.

Semiconservative Replication Define and diagram “semiconservative” as it applies to DNA replication. Copyright © 2008 Pearson Education, Inc., publishing as Pearson Benjamin Cummings.

Replication If a segment of DNA (circular or linear) is able to replicate, it must include which of the following? two double helices at least one origin of replication at least 3 million nucleotide pairs two or more mutated regions a binding site for ligase Copyright © 2008 Pearson Education, Inc., publishing as Pearson Benjamin Cummings.

Replication Enzymes In what order do the following enzymes and polypeptides function during replication? single-strand binding proteins DNA polymerase III helicase primase topoisomerase ligase DNA polymerase I Copyright © 2008 Pearson Education, Inc., publishing as Pearson Benjamin Cummings.

Replication Where and how is a new nucleotide added to the DNA strand during replication? What enzyme is needed? Copyright © 2008 Pearson Education, Inc., publishing as Pearson Benjamin Cummings.

Telomeres Telomeres, or the ends of linear chromosomes, have special structure and function, even though they are non-coding. Describe their structure and function. Copyright © 2008 Pearson Education, Inc., publishing as Pearson Benjamin Cummings.

Shortened Ends What enzyme does a gamete-producing cell include that compensates for replication-associated shortening? DNA polymerase II ligase telomerase DNA nuclease proofreading enzyme Copyright © 2008 Pearson Education, Inc., publishing as Pearson Benjamin Cummings.

Packaging Arrange the following in order of size, from smallest to largest. scaffolded domains double helix metaphase chromosome nucleosome 30 nm fiber Copyright © 2008 Pearson Education, Inc., publishing as Pearson Benjamin Cummings.

Heterochromatin Which of the following is true of heterochromatin but not of euchromatin? It is accessible to enzymes needed for gene expression. It becomes less tightly compacted after cell division. It includes DNA primarily found in expressed genes. It appears more pale when observed microscopically. It remains tightly coiled at the G1 phase. Copyright © 2008 Pearson Education, Inc., publishing as Pearson Benjamin Cummings.