+ Genital Herpes By: Katie Redinger
+ History Known for at least 2,000 years Emperor Tiberious banned kissing due to cold sores
+ History “Vocational disease of women” Not found to be a virus until the 1940s
+ History Disease became stigmatized during the 1970s Merely a cold sore in an odd place
+ What is Genital Herpes? STD caused by Herpes Simplex Virus – Type 1 or 2 Most caused by HSV-2
+ What is Genital Herpes? Herpesviridae family Similar to Hand, Foot and Mouth disease
+ What is Genital Herpes? Lays dormant in ganglion Never goes away Flare ups occur in location of exposure
+ What is Genital Herpes? Infection at one site prevents infections starting in another site. (Genital, Oral, Ocular, Whitlow) Creates antibodies
+ Structure Double stranded DNA virus Uses RNA polymerase II to create viral DNA
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+ Symptoms Break outs of blisters, chancres, and tender ulcers More serious cases affect the eye and central nervous system
+ Symptoms First outbreak usually occurs within 2 weeks of exposure May also include flu-like symptoms Frequency decreases overtime (4-5 within a year)
+ Complications Bell’s Palsy, facial paralysis, may be caused by HSV-1 Proposed Alzheimer's.
+ Transmission Contact with ruptured sores Skin to skin contact Sexual contact
+ Transmission Can occur between outbreaks Skin may contain virus without sores (small rash)
+ Transmission HSV-2 Genital to Genital HSV-1 Oral to Oral, Hand to Oral, Oral to Genital
+ Demographics 16.2 % (1/6) Americans ages have HSV-2 More common in women Transmission is more common Male Female (8-10%)
+ Demographics Worldwide rate of infection 60-90%
+ Prevention Use of condoms Abstinence
+ Living with Herpes Topical creams Vaccines are in clinical trial Antivirals
+ Sources