Drugs for Diabetes Mellitus ESAT 4001

Diabetes Type I Type II

Management of Diabetes Glucose monitoring Diet and Exercise

Insulin Administration Synthesized from recombinant DNA Absorption rate tied to injection site Recommended that injection site remain same day to day Controls insulin reactions Avoid injecting into exercising muscles Abdomen works well in exercising population

Insulin Storage and Inspection Room temperature Refrigerated after opened and not in use Visually inspect prior to use Clumping, frosting, precipitation, or color changes may = loss of potency

Insulin Injection Devices Syringe Insulin pump Prefilled insulin pen

Insulin Types Rapid-acting Short-acting Intermediate-acting Long-acting

Insulin Types and Actions

Adverse Effects Hypoglycemia Diabetic Ketoacidosis Lipohypertrophy Lipoatrophy Local skin reaction

Oral Antidiabetic Agents Type II diabetes Exercise and diet changes first Used if lifestyle modifications fail

Oral Antidiabetic Agents