What is the WHO classification for non-Hodgkin lymphoma? 10 Precursor B cell neoplasms Peripheral B cell neoplasms Percursor T cell neoplasm Peripheral T cell and NK cell neoplasm

What is the difference between leukaemia and lymphoma? 1 …

WHO classification for Hodgkin’s lymphoma. 10 Nodular sclerosis Mixed cellularity Lymphocyte rich Lymphocyte depletion Lymphocyte predominance

What type of Hodgkin’s lymphoma is most commonly associated with HIV and EBV? 15 Lymphocyte depletion.

Clinically features of a patient with NHL. 1 Painless, generalised lymphadenopathy.

You have a patient who has just presented, you think they may have HL, how likely are they to have B symptoms? 20 Commonly just present with painless lymphadenopathy. Nodular sclerosis and lymphocyte predominance are usually free of systemic symptoms (usually present stage 1 or 2). Stages III – IV, or mixed cellularity, or lymphocyte depletion are more likely to have B symptoms.

What proportion of lymphoid neoplasms are from B cells What proportion of lymphoid neoplasms are from B cells? What are the other cells of origin? 5 80-85% Most of the remainder are T cells, NK cells are quite rare.

Different types of euthanasia. 1 Active voluntary Non-voluntary Involuntary Passive

Arguments in favour of euthanasia. 1 Autonomy. Dignity. Compassion. Difference between active assistance to die and allowing a person to die is morally irrelevant. Already occurring. Palliative care is insufficient. ..

Arguments against euthanasia. 1 Life is sacred. Morale difference between killing and letting someone die. Slippery slope. Procedural safeguards against abuses are impossible to forsee. Adequate palliative care services already exist. …

Describe the process of giving bad news through the use of an acronym. Setting Perception Invitations Knowledge Explore and empathise Strategy and summary

What are we looking for on observation for a haematological examination 10 General appearance racial origin, pallor, bruising, jaundice, scratch marks

What is the pathophysiology of tumor lysis syndrome? 10 Lysis of tumor cells. Release of intracellular contents. Renal failure, multiple organ failure, death.

Clinical manifestations of hypercalcaemia. 15 Fatigue, anorexia, constipation, vomiting Vomiting, confusion, thirst and polyuria Coma, arrhythmia

Aetiology of hypercalcaemia. 15 Primary hyperparathyroidism Malignancy Drug therapy Tourniquet artefact Sarcoidosis

What is of primary concern here. 10

Outline where the hyoid bone would be. 5

Give me four causes of spleen enlargement. 1 Portal hypertension (cardiac failure?) Lymphoma Anaemia Metabolic

What are the immediate and long term complications of lymphoma treatment? 5 Immediate – nausea, vomiting, inflmaation and ulceration of mucus membranes, alopecia, pancytopenia Long term – 2degree malignancies, fertility, thyroid, hepatic or renal function

What variant of Reed-Sternbery cell occurs in Nodular sclerosis Hodgkin’s lymphoma? 50 lacunar