Hypothesis Estrogen and Progestrone are proctective factors against high systolic blood pressure which is a risk factor for the development of cardiovacular diseaes
How will participants be selected Outpatient settings i.e. doctor offices, specialty clinics Community centers Public Health clinics
Why important to study/what we don’t know There has not been much research on estrogen and a correlation to systolic blood pressure
What we know Women who are postmenopausal have an increase in systolic blood to that of men near age Women rate of CVD increase post menopause Boys on average have a higher systolic than boys Systolic stays with the person into adulthood
What pops are most affected
Study Design Cohort over 5 years Population: – 500 Women and Men aged men 250 women. – 175 middle class women/men ;175 women/men below poverty line – Non smokers for at least 8 years – Ethnicity AA Caucasion Asian-American
What comparisons will be made Compare levels of estrogen/progersteron via intravenous blood test Compare those levels of hormones to systolic blood pressure If a person develops CAD their out of the study DATA COLLECTED EVERY THREE MONTHS
Measures used to test hypothesis