Integrating ChemAxon technology into your End User Applications Java solutions for cheminformatics Ver. Mar., 2005

Broad range of products functionality Strong scientific base Ease of implementation and partnering Open licensing position Partners and Case study

Broad product range

Customer relevant applications File conversion Compound registration Internet/intranet structure editing, viewing, structural prediction and search Online publishing and education Java toolkit platform development Library Enumeration Virtual Screening Drug Design

100% Java = wide deployment range Platform independence: IBM PC, Macintosh, Linux, Solaris Database independence: Oracle, MS SQL Server, DB2, MYSQL, PostgreSQL, InterBase, Access, etc Browser independence: Internet Explorer, Netscape, Mozilla, Safari, Opera, etc

Broad range of products functionality Strong scientific base Ease of implementation and partnering Open licensing position Partners and Case study

Scientific base - People Developers: 16 (8 Phd, 6 MSc, 2 BSc) Technical expertise: –Cheminformatics –Synthetic and physico-chemistry –Virtual drug design –Java and web technology Working with clients: –Client driven development and QA for global life science leaders

Scientific base - Technology Sophisticated virtual chemistry technology High performance and capacity Broad range of format support (combine available technologies) Customizable chemistry knowledge bases Ongoing benchmarking and optimization (with users)

Broad range of products functionality Strong scientific base Ease of implementation and partnering Open licensing position Partners and Case study

Multiple deployment formats Applications Java Applets Signed Java Applets Java Web Start Java Beans Plugins JSP

Implementation support Fast support response – max. 24 hour response (fast solution also!) – via or Support Forum Skilled and relevant human support quality (direct developer to developer communications) Example implementations available Final and beta releases available online Detailed documents available online and extensive help bundled within software Freely available implementations from our site

Sales support ChemAxon available for online Webex type client presentations and teleconferences Full client support during client evaluation (developer and scientific) Flash demonstration tutorials for training and features explanation Open communications channels and professional commercial approach Established marketing support and coordination

Broad range of products functionality Strong scientific base Ease of implementation and partnering Open licensing position, easy business Partners and Case study

Flexible contracting Various commercial models to allow implementation, VARLA, OEM. Standard documentation and agreements Custom/flexible terms Flexible pricing models (annual licensing, fixed fees) Fast professional contracting

Selected Value Added Resellers

Case Study Requirement: Provide chemistry-aware components within InforSenses Knowledge Discovery Environment Solution: ChemAxons JChem Cheminformatics platform, Marvin chemical editor and viewer and calculation plugins integrated as workflow components

Case Study Chronology: Exploration: Sept 03 Contracting: Nov 2003 Launch: March 2004 First sale:March 2004 Current clients:Fujisawa Pharmaceutical Boehringer Ingelheim

Broad range of products functionality Strong scientific base Ease of implementation and partnering Open licensing position, easy business Partners and Case study

ChemScience Solutions 1 Single Scalable Software Environment for High- throughput Discovery Access best-of breed third-party components Powerful integration for cross-domain analytics Support for common industry-standard input/output formats. Query Structure Creation and Editing Full integration between structure representations and interactive browser

Flexible Application Composition Wide range of chemistry-specific components for experimentation, analysis, visualization and reporting Data pre-processing, structure format manipulation, structure-, descriptor-, and fingerprint-based processing, library enumeration using reactions rules and R-groups, and data import/export. Powerful interactive and domain specific visualizations one-click rendering of structures in interactive browser and portal. Deployment of Complete Workflows as Web Services via the Discovery Portal ChemScience Solutions 2

Workflow Building

Display and reporting

Workflow deployment

Selected Application Areas Global licenses Custom development projects Value added constructions Websites/portal front and back end Educational