AP Biology Review Mr. Brandon Boswell Cypress Bay High School Vista Park Blvd. Weston, FL 33332

Slide 2 of 46 Background  Undergrad: Philosophy & Biochemistry  Masters in Epidemiology  Adherence to Antiretroviral Therapies  HHMI (Howard Hughes Medical Institute) Cohort  Inaugural Fellow University of Florida   Identification-of-Emerging-Pathogens-by-Brandon-Boswell.pdf Identification-of-Emerging-Pathogens-by-Brandon-Boswell.pdf  Translational Medicine Institute UF   AP-Lab-6b-on-Students%E2%80%99-Knowledge-of-the-Methods-Utility-and-Application-of-Biotechnology- Techniques-by-Brandon-Boswell.pdf AP-Lab-6b-on-Students%E2%80%99-Knowledge-of-the-Methods-Utility-and-Application-of-Biotechnology- Techniques-by-Brandon-Boswell.pdf

Slide 3 of 46 AP - Background  AP Summer Institute (2007, 2008, 2009, & 2012)  Nova SE, BCPS, NCS, and Stanford University  AP Annual Conference (2008 & 2012)  2012 AP Fellow Grant recipient from College Board  AP Biology review at 2012 US DOE National Science Bowl in Washington, DC  AP Biology Test Item Contributor

Slide 4 of 46 D-Day: 5/12/14 Source: Source 2:

Slide 5 of 46 63% Pass AP Biology Exam (2013)

Slide 6 of 46 AP Biology 2013 Source:

Slide 7 of 46 The Exam SectionContentTime 1 Part A: 63 Multiple-Choice Part B: 6 Grid-Ins 90 min. Break Varies (10 min.) 2 Long Free Response = 2 Short Free Response = 6 10 min. = Reading Period 80 min. = Writing Period Source:

Slide 8 of 46 Calculator for AP Biology?  ONLY 4-function calculator (with square root)  May bring up to 2 calculators  Can be used throughout The Exam Source:

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Slide 11 of 46 Section 1  Part A  63 Multiple-Choice  4 answer choices  Understanding and Application  Answer EVERY question  No point penalty for incorrect answers  Part B  6 Grid-In questions  Calculations  Enter answers in a grid on the answer sheet Source:

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Slide 14 of 46 Reading Period (Section II)  10 min.  Questions ONLY, No response sheet  Read each Free Response Question (FRQs)  Determine which questions OR parts to answer first  Separate into 3 categories:  Clear  Translucent / Moderate  Unclear Source:

Slide 15 of 46 Essay  Multiple parts  If you do not understand a part, don’t worry.  3.5 of 10  Outline form = 0 points  Outlines will NOT be read by graders  “Only material written in the space provided will be scored.”  “Labeled diagrams may be used to supplement discussion, but a diagram alone will not receive credit.”

Slide 16 of 46 Section II  Long Free-Response  2 questions  Multipart (3 – 4)  Time: 40 min. (20 min. per question)  Short Free-Response  6 questions  Time: 39 min. (6.5 min. per question) Source:

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Slide 21 of 46 Free Response Review 1.How many Short FRQs are on the AP Exam? 1.How long should each Short FRQ take? 2.Which questions will be given to you during the Reading Period?

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Slide 24 of 46 Review  What does each of the 2 Sections of the AP Exam contain?  If you are not sure of an answer to a multiple choice question should you answer it?  How many minutes for each long FRQ?

Course Content Hour 2

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Slide 29 of 46 The Four Big Ideas  Big Idea 1 - The process of evolution drives the diversity and unity of life  Big Idea 2 – Biological systems utilize free energy and molecular building blocks to grow, to reproduce, and to maintain homeostasis  Big Idea 3 – Living systems store, retrieve, transmit and respond to information essential to life processes  Big Idea 4 – Biological systems interact, and these systems and their interactions possess complex properties Source:

Slide 30 of 46 Hierarchy of Understanding  Big Ideas (4)  Enduring Understanding (17)  Essential Knowledge (55)  LEARNING OBJECTIVES (149)

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Slide 32 of 46 Big Idea 1 - Evolution  Enduring understanding 1.A: Change in the genetic makeup of a population over time is evolution.  Enduring understanding 1.B: Organisms are linked by lines of descent from common ancestry.  Enduring understanding 1.C: Life continues to evolve within a changing environment.

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Slide 34 of 46 Big Idea 2 – Molecular Biology  Enduring understanding 2.A: Growth, reproduction and maintenance of the organization of living systems require free energy and matter.  Enduring understanding 2.B: Growth, reproduction and dynamic homeostasis require that cells create and maintain internal environments that are different from their external environments.  Enduring understanding 2.C: Organisms use feedback mechanisms to regulate growth and reproduction, and to maintain dynamic homeostasis.

Slide 35 of 46 Big Idea 2 – Molecular Biology  Enduring understanding 2.D: Growth and dynamic homeostasis of a biological system are influenced by changes in the system’s environment.  Enduring understanding 2.E: Many biological processes involved in growth, reproduction and dynamic homeostasis include temporal regulation and coordination.

Slide 36 of 46 Big Idea 3 - Genetics  Enduring understanding 3.A: Heritable information provides for continuity of life.  Enduring understanding 3.B: Expression of genetic information involves cellular and molecular mechanisms.  Enduring understanding 3.C: The processing of genetic information is imperfect and is a source of genetic variation.

Slide 37 of 46 Big Idea 3 - Genetics  Enduring understanding 3.D: Cells communicate by generating, transmitting and receiving chemical signals.  Enduring understanding 3.E: Transmission of information results in changes within and between biological systems.

Slide 38 of 46 Big Idea 4 – Biological Systems  Enduring understanding 4.A: Interactions within biological systems lead to complex properties.  Enduring understanding 4.B: Competition and cooperation are important aspects of biological systems.  Enduring understanding 4.C: Naturally occurring diversity among and between components within biological systems affects interactions with the environment.

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Slide 40 of 46 Overview of Labs  Student-Driven or Student-Directed  My goal: Guided Inquiry  Main drawback: Time Intensive  Overview and recommendations are provided in the “Lab Manual”  Your teacher may choose to do equivalent investigations rather than those in the “Lab Manual”

Slide 41 of 46 Big Idea 1: Evolution  Lab 1: Artificial Selection  Follow a plant population as you select for certain traits  Quantitatively monitor the population phenotypic frequencies  Lab 2: Mathematical Modeling  Computer based quantitative simulation of population evolution or stasis utilizing Hardy-Weinberg equations  Lab 3: Comparing DNA Sequences  Use NCBI’s BLAST (Basic Local Alignment Search Tool) to investigate evolutionary relationships between provided genetic sequences

Slide 42 of 46 Big Idea 2  Lab 4 – Diffusion & Osmosis  Surface Area & Cell Size – gelatin & phenolphthalein  Predict relative molarities of colored solutions  Plasmolysis – plant cells in hypertonic solutions

Slide 43 of 46 Big Idea 2  Lab 5 – Photosynthesis  Floating disks & photosynthetic gas production

Slide 44 of 46 Big Idea 2  Lab 6 – Cellular Respiration  Use a microrespirometer, peas (living organism), and measure O 2 consumption under different conditions

Slide 45 of 46 Big Idea 3  Lab 7: Cell Division (Mitosis and Meiosis)  Onion Root tip cells (Chi Square)  Visual investigation of HeLa cells  Soridaria images & Meiosis  Lab 8: Bacterial Transformation  I intend to do the old version, but update the analysis  Lab 9: Restriction Enzyme Digest of DNA & Gel Electrophoresis

Slide 46 of 46 Big Idea 4  Lab 10 – Energy Dynamics (I will avoid this one)  Lab 11 – Transpiration (Not on AP Exam?)  Guided Inquiry - Fruit flies & Water bottles  Lab 12 – Animal Behavior  Made for Open inquiry  Lab 13 – Peroxidase (Enzyme) Activity