M-Phase Prophase – Metaphase – Anaphase – Telophase Prophase chromatin begins to tightly coil (condenses) nuclear envelope begins to disappear nucleoli disappear each chromosome is now a complex of sister chromatids mitotic spindle begins to form centrosomes move away fro each other Prometaphase nuclear envelope fragments microtubules move through the nuclear area through the center of the cell each sister chromatid complex is now connected to a microtubules by the kinetochore region of the centromere

M-Phase Metaphase longest phase of Mitosis centrosomes are now at opposite sides of the cell chromosomes are located at the metaphase plate (center) kinetochores of the sister chromatids are now attached to tubules of opposite centrosomes microtubule complex is now called the spindle

M-Phase Anaphase shortest phase of Mitosis sister chromatids are pulled apart as the spindle fibers shorten the separated chromosomes migrate toward the opposite poles at the end of anaphase the polar regions of the cell have equivalent amounts and types of chromosomes

M-Phase Telophase the 2 daughter cell nuclei begin to form nuclear envelopes begin to form from the parent fragments chromosomes become less condensed mitosis is complete with the completion of the 2 nuclei regions

M-Phase Cytokinesis the cell divides at the cleavage furrow shortly after Mitosis Pinching in of the plasma membrane Cell plate forms in plants Becomes the cell wall