SKOV-3, 48h CaOV-3, 48h BG-1, 48h Concentration (µM) Viable cells (%) SW 43 SW IV-52s SW III-123 SW 43 + SW IV-52s SW 43 SW IV-52s SW III-123 SW 43 + SW IV-52s SW 43 SW IV-52s SW III-123 SW 43 + SW IV-52s A C B Figure 1

Actin Phospho NF- B p65 SW III-123 ( M) min Figure 2

CaOV-3 cells A Figure 3 SW 43 SW IV-52s SW III-123 Caspase 3 activity (fold) - TNF Ab + TNF Ab SW 43 SW 43 + TNF Ab Viable cells (%) B SW 43 (µM) SW IV-52s SW IV-52s + TNF Ab Viable cells (%) C SW IV-52s (µM) SW III-123 SW III TNF Ab Viable cells (%) D SW III-123 (µM)

SW 43 SW IV-52s SW III-123 Caspase 3 activity (fold) - TNF Ab + TNF Ab BG-1 cells A SW 43 SW 43 + TNF Ab Viable cells (%) B SW 43 (µM) SW IV-52s SW IV-52s + TNF Ab Viable cells (%) C SW IV-52s (µM) SW III-123 SW III TNF Ab Viable cells (%) D SW III-123 (µM) Figure 4