Acinic Cell Carcinoma of the Parotid Gland Metastatic to the Epidermis of the Back Pilcher R. Davidson MJC. Department of Oral and Maxillofacial Surgery,

Slides:



Advertisements
Similar presentations
The Thyroid Incidentaloma
Advertisements

Adult Neck Masses Justin Dumouchel 9/14/05.
Malignant Adenomyoepithelioma of the Breast with Lymph Node Metastasis
Case Report History :26 year old caucasian male presented complaining of an intra oral swelling involving the gum margin of the upper left jaw. He gave.
AJCC Staging Moments AJCC TNM Staging 7th Edition Lung Case #3 Contributors: Valerie W. Rusch, MD Memorial Sloan-Kettering Cancer Center, New York, New.
Joint Hospital Surgical Grand Round 21 st July, 2012 RH.
Cancer of middle ear Chunfu Dai M.D & Ph.D. Background Primary tumor in middle cavity Primary tumor in middle cavity Predilection in y Predilection.
Salivary Gland Tumors.
Update on 18 F-Fluorodeoxyglucose/Positron Emission Tomography and Positron Emission Tomography/ Computed Tomography Imaging of Squamous Head and Neck.
TUMOURS OF NASAL CAVITY & PARANASAL SINUSES
Ovarian Cancer May 2007 Dr Anna Winship Guy’s & St. Thomas’ NHS Trust Click Here For First Question Oncology Registrars’ Forum “Best of Five”
Adult Neck Masses Ian Paquette MD DHMC PGY 3-5 Teaching Conference 12/20/2006.
SYB Case 2 By: Amy. History 63 y/o female History of left breast infiltrating duct carcinoma s/p mastectomy in 1996 and chemotherapy ER negative, PR negative,
Chapter 28 Lung Cancer. Mosby items and derived items © 2009 by Mosby, Inc., an affiliate of Elsevier Inc. 2 Objectives  Describe the epidemiology of.
Salivary gland diseases
 Gender: Female  Age: 35  James  Oncor  Single  Smoked for 8 years  Quit in 2004  No alcohol or drug use  Family  Mother: breast cancer  Sister:
USEFULNESS OF MRI IN THE DIAGNOSIS OF SALIVARY GLAND PATHOLOGIES
WORK UPS. Ultrasound method of choice for the differentiation of cysts from solid masses and for guidance in interventional procedures. Benign: – solid.
Introduction Oesophageal duplication cysts are rare congenital oesophageal anomalies in adults and are mostly asymptomatic. Diagnosis of an oesophageal.
Oral cavity The majority of tumors in the oral cavity are s.c.c.
4.1b. Pre-contrast Axial T1 Wtd MRI4.1c. Post-contrast Axial T1 Wtd MRI4.1a. Axial T2 Wtd MRI 4.1d. Post-contrast Sagittal T1 Wtd MRI Patient with Intra-cranial.
Head And Neck. Salivary gland Tumours Epithelial Epithelial Benign Benign Pleomorphic adenoma (Mixed parotid) Pleomorphic adenoma (Mixed parotid) Monomorphic.
Case study: lymphoma/ granulomatous disease
Leiomyosarcoma of the Vulva Bapir M, Hoh J & Al-Inizi S
Principles of Surgical Oncology Done by : 428 surgery team surgery team.
Grading And Staging Grading is based on the microscopic features of the cells which compose a tumor and is specific for the tumor type. Staging is based.
Cancer 101: A Cancer Education and Training Program for American Indians & Alaska Natives Cancer 101: A Cancer Education and Training Program for American.
NECK MASSES.
1. Clinical Impression? Differentials?. Thyroid Carcinoma commonly manifests as a painless, palpable, solitary thyroid nodule The patient's age at presentation.
NEOPLASIA CASES. CASE 1 A 20 year old female presented with a round mobile breast lump. She has no family history of breast cancer Question : What test.
Role of Sentinel Lymph Node Biopsy in the Staging of Synovial, Epithelioid, and Clear Cell Sarcomas. Ugwuji N. Maduekwe, Francis J. Hornicek, Dempsey S.
Clinical History Patient presents with a palpable upper abdominal mass Patient states possible clinical history of abdominal hernia.
Anaplastic thyroid cancer based on ATA guideline for Management of Patients with ATC. Thyroid. 2012;22: R3 이정록.
It is essential to obtain the exact history of the hypersalivation as well as a thorough and complete past medical history. Oral evaluation should be performed,
CASE 1: type A thymoma 83 year old woman. CT images show well defined mass with homogeneous enhancement that contains lobules. Note also fatty plane.
제 75 회 소화기 내시경 학회 월례 집담회 나윤주, 심기남, 강민정, 정지민, 하창윤 정해선, 백수정, 송현주, 염혜정, 정성애, 유권 이화여자대학교 부속 목동 병원 소화기 내과.
Supraclavicular metastasis from urothelial bladder carcinoma: A case report S. Farmahan, T. Mirza, P. Ameerally Oral Maxillofacial Department, Northampton.
Authors: Syed H. Jafri ¹, Angel I. Blanco¹, Bonnie A. Labdi², Shan Guo¹. UT Houston department of medicine, Division of Oncology Department of Pharmacy.
Sjogren’s syndrom  It is an autoimmune disease causing destruction of the salivary and the lachrymal g  Either primary or secondary to C T disease.
KCP 778 토의자 가천대 길병원 R3 강명희 2013 년 4 월 5 일 세포병리학회 월례집담회.
University of Pennsylvania Department of Orthopaedic Surgery Joseph King, Eileen Crawford, Abass Alavi, Arthur Staddon, Lee Hartner, Richard Lackman and.
Submandibular gland: Surgical Anatomy Tumors Surgery
Brain imaging prior to lung cancer resection
Metastatic sarcoma to the nasal bone
Advanced loco regional Regional breast cancer
A Rare Case of Askin’s Tumor in the 6th rib
Case of the Month 19 January 2017
Basile Pache, Antonia Digklia*, Nicolas Demartines, Maurice Matter.
Radio Iodine Therapy In Cancer Thyroid
Case scenario- Breast Lump
A diagnostic challenge: an incidental lung nodule in a 48-year-old nonsmoker Blake Christianson1, Smeet Patel MD1, Supriya Gupta MD1, Shikhar Vyas MD2,
Chest Wall Tumors.
Fig. 1c: Cystoprostatectomy specimen
NECK MASSES.
“CASE SERIES OF EGFR MUTATIONS IN SQUAMOUS CELL CARCINOMA LUNG ”
SOLITARY CYSTIC LYMPH NECK NODE METASTASIS OF OCCULT THYROID PAPILLARY CARCINOMA González-García R, Cho-Lee GY, Naval-Gías L, Rodríguez-Campo FJ, Sastre-Pérez.
2epart EXTRAPULMONARY SMALL CELL CANCER OF THE ESOPHAGUS INTRODUCTION
23 yo w/ widespread liver metastasis
Dr T P E Wells 13 July 2018 Breast SSG Bath
POEM Group Online Case Discussion Date: April 1, 2014
Otolaryngology referred this patient for imaging after palpating a mass in the “left parotid tail.” Axial contrast-enhanced CT scan through the mass reveals.
Case 1 South Bay Pathology Society May 2009
Malignant odontogenic tumors
Radiological imaging in primary parotid malignancy
Multiple (type 3) cyst-related primary lung malignancies presenting as cystic airspaces with asymmetrical or circumferential wall thickening. a, b) A 52-year-old.
R.J.I Colville, I.G Camilleri, N.R McLean, J.V Soames 
General strategies of Cancer Treatment and evaluation of Response
Serial imaging before and after immunotherapy among patients with MDM2/4 amplifications (N = 6). Serial imaging before and after immunotherapy among patients.
Presentation transcript:

Acinic Cell Carcinoma of the Parotid Gland Metastatic to the Epidermis of the Back Pilcher R. Davidson MJC. Department of Oral and Maxillofacial Surgery, Taunton and Somerset Hospital, UK. Acinic cell carcinoma (ACC) of the parotid is reported with multiple metastases including rare spread to the contralateral orbit and the epidermis of the back Case Report 54 year old Caucasian female presented with a right asymptomatic parotid mass of 2 month’s duration with no other neck masses nor lymhadenopathy. Fine needle aspirate suggested an epithelial neoplasm. Histology following a partial parotidectomy demonstrated ACC (figure 1). More radical surgery and investigations were advised. MRI scan of the head and neck could not exclude residual tumour and an incidental finding was a 1 cm lesion in the contralateral orbit (figure 2). Ophthalmic opinion was sought and a working diagnosis of a cystic lesion was obtained. A right total parotidectomy and excision of the contents of the right submandibular triangle plus supramental node sampling were performed. Histology reported an island of tumour within the excised right submandibular gland. Postoperative adjuvant radiotherapy was provided. Progressive diplopia developed during the following four months and fundoscopy revealed signs consistent with a retrobulbar mass. A repeat MRI scan demonstrated an enlargement of the orbital lesion (figure 3). Biopsy of the orbital lesion reported ACC. (figure 4). CT scan of abdomen and chest excluded any other primary site and radiotherapy was performed to the left orbit. 18 months later a mass on her lower back was histologically demonstrated as being metastatic disease and was followed by a further deposit on her upper back 2 months later. A further MRI scan was undertaken and this demonstrated multiple cerebral metastases (figure 5). A decision was taken not to proceed with further radiotherapy or to provide chemotherapy. References 1.Saxena RB, Mathur RN, Sonani SZ. Orbital metastasis of mixed parotid tumor. Indian J Ophthalmol.1975;23(2): Thomas KM, Cumberworth VL, McEwan J. Orbital and skin metastases in a polymorphous low grade adenocarcinoma of the salivary gland. J Laryngol Otol. 1995;109: Spiro RH, Huvos AG, Strong EW. Acinic cell carcinoma of salivary gland origin: a clinicopathologic study of 67 cases. Cancer.1978; 41: Discussion Two previous reported cases of distant metastasis from parotid gland tumor to the orbit are in the literature but none have been found to the epidermis of the back 1,2. ACC represents approximately 5% to 17% of all salivary gland cancers. Spiro et al 3 reported a distant metastasis rate of 12% mainly to lung, bone and brain. This case demonstrates the very aggressive nature of ACC and the importance of wide diagnostic imaging in treatment planning. Figure 4: Metastatic deposit of acinic cell tumor in orbital connective tissue (haematoxylin- eosin, original magnification x 200). Figure 1: Acinic cell tumour arising in the parotid tissue with a small group of normal parotid acini (bottom left) (haematoxylin–eosin,original magnification x 200) Figure 2: Axial magnetic resonance image of the orbits showing a lesion approximately 1cm in diameter in the left orbit. Figure 3: Axial magnetic resonance image of the orbits showing considerable enlargement of the tumor, causing displacement of the optic nerve and the globe. Figure 5: Axial magnetic resonance imaging demonstrating increase in size of original lesions and new lesions in the right orbit laterally, right temporal lobe and right vertex.