MBV2010/BIO2140 Colloquium, April 9. RULES Multiple choice Only one correct answer 30-60 seconds to answer No textbook, computer, mobile phone, please.

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Presentation transcript:

MBV2010/BIO2140 Colloquium, April 9

RULES Multiple choice Only one correct answer seconds to answer No textbook, computer, mobile phone, please There will be a prize for the group with the most correct answers.

Most small nuclear RNA genes are transcribed by A RNA polymerase I B RNA polymerase II C RNA polymerase III D RNA polymerase IV 1

Most small nuclear RNA genes are transcribed by 1

The carboxy-terminal domain of RNA polymerase II consists of a repeated A heptapeptide (7 repeats) B hexapeptide (6 repeats) C octapeptide (8 repeats) D decapeptide (10 repeats) 2

The carboxy-terminal domain of RNA polymerase II consists of a repeated 2 Tyr-Ser-Pro-Thr-Ser-Pro-Ser

The human CTD consists of A 27 repeats B 32 repeats C 45 repeats D 52 repeats 3 Tyr-Ser-Pro-Thr-Ser-Pro-Ser

The human CTD consists of 3 Tyr-Ser-Pro-Thr-Ser-Pro-Ser

The TATA-binding protein (TBP) is part of A Transcription factor IIA B Transcription factor IIB C Transcription factor IID D Transcription factor IIE 4

The TATA-binding protein (TBP) is part of 4

FACT is a protein complex involved in A Transcription B Replication C Translation D Recombination 5 ?

FACT is a protein complex involved in 5 FACT = facilitates chromatin transcription

The rho protein mediates A Initiation of transcription B Initiation of replication C Site-specific recombination D Termination of transcription 6

The rho protein mediates 6

Which type of intron does not require a branch site for splicing? A Group I introns B GU-AG introns C AU-AC introns D Group II introns 7

Which type of intron does not require a branch site for splicing? 7

Which of the following proteins plays a role in splice site selection? A snRNPs B SR proteins C Sxl protein D U2 8

Which of the following proteins plays a role in splice site selection? 8

Amino acids are linked to tRNAs at A the 5’ terminus of tRNAs B the adenine base at the 3’ terminus C the ribose at the 3’ terminus D the phosphate linking the 3’ terminal nucleotides of tRNAs 9

Amino acids are linked to tRNAs at 9

Which of the following components of the translation machinery has proofreading capability? A ribosomal RNAs B ribosomal proteins C translation initiation factors D tRNA synthetases 10

Which of the following components of the translation machinery has proofreading capability? 10

Peptide bond formation is catalyzed by A ribosomal RNA B ribosomal proteins C translation factors D all of the above 11

Peptide bond formation is catalyzed by 11

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