DATRI ACT NOW. GIFT A LIFE.

DATRI’s MISSION Create Awareness About Blood Stem Cell Donation Build A Diverse Donor Registry Help Find a Match for Patients globally in Need of A Stem Cell Transplant to cure Blood Cancer and other Blood related disorders

Co-Founders of DATRI - Raghu Rajagopal – CEO – DATRI – Founder of Energeate, Secretary TiE Chennai Chapter, Program Manager – Chennai Fund, Mentor and Board Member – Startups in the Education space - Dr. Nezih Cereb –Chairman – DATRI - President, Co-Founder Histogenetics, Background in clinical research especially bone marrow transplant, Research Scientist with a key role in enabling HLA Class I DNA typing feasible, internationally recognized for introducing and implementing latest technologies for HLA typing. - Dr. Soo Young Yang – Chairman – DATRI - Chairman, Co- Founder of histogenetics, over 25 years of extensive research experience in HLA genetics, pioneered the development of molecular typing methods for HLA.

WHAT WE DO ? Make people aware, about why and how to become a donor. Educate them about the process involved to become a donor. Collect Buccal Swab sample from them with their consent. help find a match for a patient in need.

WHAT IS A DONOR REGISTRY ? A DONOR REGISTRY is a database of individual potential donors. There exists various donor registries across the globe but no functional Registry in India. DONATE WHAT ? A donor is required to donate stem cells usually through peripheral blood stem cell transplant.

What are stem cells ? Stem cells have the remarkable potential to develop into many different cell types in the body like blood cells, muscle cells etc.. Serve as a repair system for the body A blood cancer patient’s stem cells are destroyed by radiation in chemotherapy and they require them from a donor to help keep him alive.

Why should I donate? 25% of patients in need of a transplant usually find a donor within their family.But, 70%of the patients usually look for a match among unrelated donors. Your choice to become a DONOR can therefore help save a life.

How do you determine if I am a ‘MATCH’ ? When you donate your sample, we perform necessary experiments to determine your genetic information (tissue typing). Your tissue typing is then matched with that of the patients. A close match is required to enable a successful transplant.

How do I donate stem cells ? Peripheral blood stem cells transplant is usually performed where the stem cells from your blood stream are filtered and infused into the patient. It’s a simple process like donating blood. You can usually return back to your day-to-day life immediately

THE NEED FOR YOU TO BE A DONOR? The probability of finding a possible match for a stem cell transplant depends largely on factors like ethnicity, genealogy etc. Every major donor registry across the world is in need of diverse ethnic groups to register as potential donors. South Asians for instance have a chance of 1 in to find a possible donor.

DONOR SAMPLE COLLECTION Buccal swab sample – a cotton swab is rubbed inside your cheek. Processing sample – it is processed in our state of the art lab at histogenetics to determine your genetic information. Potential match – your genetic information is matched with that of the patient in need, to check for a possible match.

TRANSPLANT PROCESS ONCE A POSSIBLE MATCH IS FOUND- Educate the donor about the process Ensure the DONOR is healthy through medical examinations. DONOR’s health is the top priority. No OBLIGATION for the donor to go through the process if he/she is not INCLINED

What next after you find my typing information?. Your HLA Type will be shared with you. You may have an opportunity to save a life. This may be helpful for your own family or friends. Currently there are many patients in India in need of a Match – Here are a few of them –. Gaurav Tandon – 34 year old – Mumbai. Venkat Ramani – 41 year old – Mumbai. Rohit Sehgal - 30 Year Old – New Delhi. Vibhasith – 3 year Old – CMC hospital. Chamood - 13 year Old – CMC hospital. IF you are a MATCH DATRI will contact you to explain the next steps

RIGHT TO REFUSE ! IF YOU ARE A POSSIBLE MATCH TO A PATIENT, YOU WILL BE CONTACTED BY THE REGISTRY AND EXPLAINED THE TRANSPLANT PROCESS THOROUGHLY. AT ANY GIVEN POINT OF TIME, YOU ARE FREE TO WITHDRAW FROM DONATING YOUR STEM CELLS.

NO COST !!! THE COMPLETE COST OF THE TRANSPLANT PROCESS IS COVERED BY THE PATIENT’S MEDICAL INSURANCE.

CONFIDENTAILITY Once you register as a donor - We assure that your information is safe with us. You are our priority! We highly appreciate your commitment and your noble choice to save a life. We respect your privacy.

DATRI ACT NOW. GIFT A LIFE.