Structure of Muscle. Sliding Filament Hypothesis n During Contraction n Proteins DO NOT actually shorten n Rather they slide past one another n Support.

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Presentation transcript:

Structure of Muscle

Sliding Filament Hypothesis n During Contraction n Proteins DO NOT actually shorten n Rather they slide past one another n Support n Changes in Sarcomere Bands n Actual measurement of proteins n Length-Tension Characteristics

Sliding Filament Hypothesis n During Contraction n Proteins DO NOT actually shorten n Rather they slide past one another n Support n Changes in Sarcomere Bands n Actual measurement of proteins n Length-Tension Characteristics

Length - Tension Characteristics n Stretch Muscle to Various Lengths n Measure Active Tension Sarcomere Length Tension

Troponin - Tropomyosin Complex Myosin Head Myosin Binding Site Actin Tropomyosin Filament T C I Ca Binding Sites

Troponin - Tropomyosin Complex Myosin Head Myosin Binding Site Actin T C I Ca

Troponin - Tropomyosin Complex Myosin Head Myosin Binding Site Actin T C I Ca

Troponin - Tropomyosin Complex Myosin Head Myosin Binding Site Actin T C I Ca

Plunger Model for Release of Ca ++ from SR Ca Ca Ca ATP Ca Dihydropyridine Receptor Ryanodine Receptor

Summary of Excitation-Contraction Coupling Ca

Muscle Mechanics – Series Elastic Component (SEC)

Variation in Muscle Tension

Muscle Fiber Types Type I Type IIa Type IIb

Braided Pneumatic Actuator

Colburn Test Rig

Length – Tension Characteristics

Festo Actuators

Air Insect - Kirchner

Buckling

Mini-Braided Pneumatics: Matt Birch and Alan Pollack

Electroactive Polymer – SRI et al