ACP PRESENTATION 2012 – Steroids and Leflunomide, Not Biologics Are The Major Risk Factors For Infection Following Total Joint Arthroplasty Ranjani Somayaji.

Slides:

Advertisements

Similar presentations

Shafiepour,mohsen MD. Kerman university of medical sciences.

Advertisements

Surgical Infection Prevention Project Team: Anesthesia Infectious Disease Pharmacy Surgical Services Labor & Delivery Quality Resource Management Center.

-HA -HB -Factor XI deficiency -Factor II deficiency -Factor V deficiency -Factor XIII deficiency -Factor VII deficiency Dental problems in Hemophilia.

Wrap-Up and Post Course Self Assessment Dr. Diane Lacaille.

Regional anaesthesia after total hip and knee replacement: Analysis of pain and treatment related side-effects from the Pain-out registry K. Donauer (1,3)

Orthopedic Joint Replacement: Applications and Challenges Peter Ping Liu, Ph D, PE, CQE, OCP and CSIT Professor and Coordinator of Graduate Programs School.

Complication after Procedure Resident Name, MD Attending Name, MD Institution Morbidity & Mortality Conference Date.

DR.IBTISAM JALI MEDICAL DEMONSTRATOR

Erik Haley Epidemiology of Chronic Diseases March 11, 2013.

Surgical Site Infection Prevention Orthopaedic Joint Surgery Patients Orthopaedic Quality Improvement Committee Dr Steven Rabin Dr Anthony Rinella Paul.

By: Brandon Jamison, Tucker Dodson, Nami Small.  There are several conditions can cause elbow pain and disability, and lead patients and their doctors.

Orthopedic Quality Initiatives

Part III Amy L. McIntosh, MD Pediatric Orthopedic Surgeon Mayo Clinic Rochester, Minnesota.

Osteoarthritis (OA) Dr. Timothy Payne, MD. What is Osteoarthritis? Osteoarthritis is primarily a non- inflammatory degenerative disorder of moveable joints.

44 y/o female, Known case of Addison's disease, For elective cholecystectomy. How to optimize the patient’s state during the surgery?

A New Oral Direct Thrombin Inhibitor, Dabigatran Etexilate, Compared With Enoxaparin for Prevention of Thromboembolic Events Following Total Hip or Knee.

Ankle Joint Prosthesis Sarah Lovell- BME281 Presentation 1.

Interventions for Clients with Connective Tissue Disease and Other Types of Arthritis.

Preventing Surgical Infections Through Effective Perioperative Antibiotic Administration Project Team Members: Anesthesia Infectious Disease Pharmacy Surgical.

Project JOINTS: Joining Organizations IN Tackling SSIs Screen patients for Staph aureus (SA) carriage and decolonize SA carriers with five days of intranasal.

Rheumatoid Arthritis Dr Chandini Rao Consultant Rheumatologist.

© Copyright, The Joint Commission 2014 National Patient Safety Goals.

Assistant Professor Dr Kapil Mani KC

Intra-wound Vancomycin Powder Significantly Reduces the Risk of Infection in Growth-friendly Surgery John T. Smith, MD Justin Haller, MD Angela Presson,

The Risk of Cancer Following Total Hip or Knee Arthroplasty by Ravi Tharani, Frederick J. Dorey, and Thomas P. Schmalzried J Bone Joint Surg Am Volume.

Advances in the Treatment of Crohn’s Disease GASTROENTEROLOGY 2004;126:1574–1581.

Jose S. Santiago M.D.. Total Knee Replacement Total Knee Arthroplasty- surgical procedure to replace the weight-bearing surfaces of the knee joint - the.

8 Things to Know About Knee Replacement Surgery

Juvenile Idiopathic arthritis and infectious arthritis 郭三元 Division of R-I-A TSGH.

Dr. L. K. Lelei Specialist Orthopaedic Surgeon Moi University, School of Medicine.

Making Surgery Safer: Preventing Post Operative Myocardial Infarction Departments: Anesthesia, Cardiology, General Surgery, Orthopaedics, Primary Care,

Orthopaedics at The Bon Secours, Cork

CURRENT CONCEPTS IN PERI-OPERATIVE TKA MANAGEMENT

Hip & Knee OA: 5 Pearls to Delay the Dreaded Total Joint Replacement

Arthritis and the Management of the Painful Knee

Total Knee Replacement

Abstract # Rates of Complications and Required Additional Surgical Interventions after Surgical and Nonsurgical Treatment in Lumbar Spondylosis:

Incidence and Predictors of Surgical Site Infections Following Foot and Ankle Surgery at a Tertiary Care Center in Riyadh, Saudi Arabia AlKenani NS, AlSultan.

Treatment Goal of treatment reduce inflammation and pain

Ochsner Health System- Orthopedics Division Research Studies

3rd National Rheumatology Congress of Kosova with International participants: November 3-4, 2016 Emerald Hotel, Prishtina, KosovoReumatology 2016 COMPLICATIONS.

Infected total knee arthroplasty (TKA) with antibiotic cement spacer

KNEE ARTHRITIS IS CURABLE

Menachem M Meller,MD, PhD

PPT - Leading Joint Replacement Center – The Knee Klinik

Total Hip Replacement Surgery – Introduction,process,benefits

Maggie Davis Hovda, MD 3/22/2010

Benefits of autotransfusion

Material Challenges for Biomedical Applications: An Example

Diagnosing Rheumatoid Arthritis Early

Figure 1 Rheumatoid arthritis development over time in relation to the level of inflammation Figure 1 | Rheumatoid arthritis development over time in relation.

Nat. Rev. Rheumatol. doi: /nrrheum

Continuous Infusion Pumps For Post-Operative Pain Control Oksana Sidorevich, RN State University of New York Institute of Technology Abstract A large.

Connect and learn more at

Risk factors for cryptococcal infection among patients with rheumatoid arthritis receiving different immunosuppressive medications T.-L. Liao, Y.-M.

Rheumatoid Arthritis 2015 Guidelines What's New? What's Different?

What’s new in my specialty- Rheumatoid Arthritis

Nat. Rev. Rheumatol. doi: /nrrheum

Volume 4, Issue 4, Pages (December 2018)

Who, where, why, and the data behind it.

Infections and Biologic Therapy in Rheumatoid Arthritis

Updates in RA, PsA, and Biosimilars

Prevention of Postoperative Recurrence in Crohn's Disease

Septic Arthritis and Prosthetic Joint Infections in Older Adults

The following medical conditions require antibiotic prophylaxis for dental procedures where bacteremia could occur such as after manipulation of gingiva.

Risk factors for postoperative infection after lower gastrointestinal surgery in patients with inflammatory bowel disease: Findings from a large epidemiological.

Aminocaproic Acid (Amicar) vs

Understand the Burden Total Knee Arthroplasty (TKA) Disease in India with HBG.

Presentation transcript:

ACP PRESENTATION 2012 – Steroids and Leflunomide, Not Biologics Are The Major Risk Factors For Infection Following Total Joint Arthroplasty Ranjani Somayaji B.Sc.PT., MD

Disclaimer  Wishing I had one?...  Residency Salary?

Background  Rheumatoid arthritis (RA) patients are at risk for infectious complications following orthopedic procedures due to underlying co-morbidities & RA treatment  The effect of biologic therapies on the risk of infections is still controversial… Goh L, Jewell T, Laversuch C & Smanta A. Should anti-TNF therapy be discontinued in rheumatoid arthritis patients undergoing orthopaedic surgery? A systematic review of the evidence. Rheumatol Int 2012;32:5-13.

Objective  To determine whether biologic therapies increase the risk of postoperative infection (surgical site or any site) in RA or adult juvenile idiopathic arthritis (JIA) patients undergoing hip or knee total joint arthroplasty

Methods  Subjects: RA/JIA undergoing hip or knee TJA between January 1, 2000 – December 31, 2010  Total of 381 procedures in 259 patients performed  Demographic + clinical data collected for up to 1 year

Hypothesis  Patients with RA on biologic therapy will have an increased incidence of post-operative infection following hip or knee TJA as compared with RA patients on standard disease modifying agents…

Table 1

Results – Part 1 Relative Risk for Infection Following Total Joint Arthroplasty by Therapy

Results – Part 2 Relative Risk for Infection Following Total Joint Arthroplasty by Comorbidity

Discussion  Biologic therapy & underlying co-morbidities do not confer an increased risk of post-operative infection in RA patients undergoing hip or knee total joint arthroplasty  Moderate to high dose steroids & leflunomide increase the risk of infection  Limitations…  Future studies….

QUESTIONS? Thank you to Dr. Liam Martin & Dr. Cheryl Barnabe