Design by DNA an analogical approach to design Damian Rogers.

Slides:



Advertisements
Similar presentations
Chapter 16 Evolutionary Theory.
Advertisements

Evolution of Biodiversity
Lesson Overview 1.3 Studying Life.
NATURAL SELECTION SC.912.L Additional Site for EOC Help:
Unit 7: Evolution.
Evolution by Natural Selection
Topic 4. Learning objectives: By the end of the lesson you should be able to: Explain the impact of the environment on the phenotype of an organism. Describe.
Evolution.
Theory of evolution Evolution- process to explain change over time Theory-Well supported testable explanation.
Lecture 28 Evolution. Variation Without variation (which arises from mutations of DNA molecules to produce new alleles) natural selection would have nothing.
EVOLUTION. EVOLUTION The first living organisms were simple, single celled organisms. Through time more complex simple- celled creatures were created.
Unit 1: The Language of Science  communicate and apply scientific information extracted from various sources (3.B)  evaluate models according to their.
Natural Selection Developed by Charles Darwin in 1859
BIODIVERSITY + EVOLUTION Chapter 4. BRIDGING THE GAP  Biodiversity is all of the differences amongst the living world.  So how do topics already covered.
The Mechanics of Evolution Interaction of Natural Selection and Inheritance (Genetics)
Evolution. What is evolution? A basic definition of evolution… “…evolution can be precisely defined as any change in the frequency of alleles within a.
Section 3: Beyond Darwinian Theory
Ecology Ecological valance M. Saadatian.
Evolution. Artificial selection- humans select which traits will be passed on Natural selection- the environment determines which traits will be passed.
A Natural Approach to Design A DNA-Based Analogy for the Design of Sustainable Artifacts Presented by: Dr. Filippo Salustri Associate Professor, Ryerson.
Evolution Earlier Theories. WHY EVOLUTION? Evolution as a PROCESS is a SETTLED THEORY accepted by biologists all over the world. Evolution provides a.
The lives of gray-headed flying foxes are closely entwined with the lives of the eucalyptus trees that form their habitat –Eucalyptus trees provide food.
Sources of Inherited Variation Mutations & Sexual Reproduction.
Biology EOC Review Evolution. Evolution Explain biological evolution as the consequence of the interaction of population growth, inherited variability.
Genetics and Speciation
Evolution What role does the environment play in an organism’s survival, reproduction and evolution?
Natural Selection. In science, theories are statements or models that have been tested and confirmed many times.
Mechanisms of Population Evolution
EVOLUTIONEVOLUTIONEVOLUTIONEVOLUTION. Questions to Ponder TRUE/FALSE 1. You can web your hands if you try. 2. You can acquire traits in your lifetime.
EVOLUTION AND NATURAL SELECTION. QUICK REVIEW SUMMARY OF THE HISTORY OF EVOLUTIONARY THOUGHT.
Introduction to History of Life. Biological evolution consists of change in the hereditary characteristics of groups of organisms over the course of generations.
Evolution Biology Mrs. Zuck. Evolution by Natural Selection  Organisms tend to be well suited to where they live and what they do.  How do they become.
Click on a lesson name to select. The Study of Life Section 1: Introduction to Biology Section 2: The Nature of Science Section 3: Methods of Science.
Multiple Choice Short Answers Fill in the blink DefinitionBONUS! Bonus! 1070.
Biological Change Over Time
Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings Evolution, Biodiversity and Extinctions.
Themes of Biology. Biology 1.1 Themes of Biology  Everyday, you are surrounded by living things that scientists call organisms. Some organisms; such.
Evidence for Evolution Review of Natural Selection.
Natural Selection. Evolution by Natural Selection.
Ch.10: Principles of Evolution
Essential Questions What is biology? What are possible benefits of studying biology? What are the characteristics of living things? Introduction to Biology.
Agents of Evolutionary Change Mutation What is a mutation? Changes to the nucleotide sequence in the genetic material of an organism that.
Day 1 – Introduction to Biology
Chapter 23 Evolution. » A population has been described as a group of individuals of the one species that breed together in an environment (fertile offspring)
Jean-Baptiste Lamarck a French botanist a French botanist Lamarck’s Theory: Inheritance of Acquired Characteristics Lamarck’s Theory: Inheritance of Acquired.
Genetic Variation. KEY CONCEPT A population shares a common gene pool.
Lesson # 7: Evolution (Processes + Patterns of Evolution)
Ms. Hughes.  Evolution is the process by which a species changes over time.  In 1859, Charles Darwin pulled together these missing pieces. He was an.
Natural Selection and the Evidence of Evolution (15.1) Evolution Foldable 1.Fold 4 pieces of paper, so you have 7 layered flaps 2.Write “Evolution” on.
Evolution of Populations. Individual organisms do not evolve. This is a misconception. While natural selection acts on individuals, evolution is only.
Evolution of Populations
Evolution for Beginners. What is evolution? A basic definition of evolution… “…evolution can be precisely defined as any change in the frequency of alleles.
Natural Selection A Mechanism for Evolutionary Change.
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Chapter 1 Lecture Slides.
LECTURE 9. Genetic drift In population genetics, genetic drift (or more precisely allelic drift) is the evolutionary process of change in the allele frequencies.
Evolution, Biodiversity and Extinctions
Evolution for Beginners
Biology is the scientific study of life
The Environment and Change Over Time
7th Grade Cells Natural Selection
Inheritance and Variation of Traits
Unit 5 Evolution Fossil record Natural Selection
Natural Selection in Populations
Charles Darwin ( ) Sailed around the world
Evolution Standards Rachel Tumlin.
What leads to variation among species?
The “A” TEAM Ecology TEST.
EVOLUTION Definition - A gradual change over a period of time
Evolution by Means of Natural Selection
Presentation transcript:

Design by DNA an analogical approach to design Damian Rogers

What is Design by DNA? Method to design the functional form of a product Method to design the functional form of a product IE: the characteristics a product must have in order to describe its function in relation with requirements (do 0-60 in 3s) IE: the characteristics a product must have in order to describe its function in relation with requirements (do 0-60 in 3s) There is also the aesthetic form (be aesthetically pleasing) There is also the aesthetic form (be aesthetically pleasing) Uses an analogy to biological DNA Uses an analogy to biological DNA Promotes faster “cookie-cutter” design Promotes faster “cookie-cutter” design Allows a more direct approach to novel designs Allows a more direct approach to novel designs

Why an analogy? Engineering design problems are becoming increasingly complex Engineering design problems are becoming increasingly complex Need a way to lower the complexity into easier to handle portions Need a way to lower the complexity into easier to handle portions Analogies lower problem complexity Analogies lower problem complexity relates a problem to something that is familiar or well-known relates a problem to something that is familiar or well-known

Why a DNA analogy? The “building blocks of life” – building blocks of artefacts The “building blocks of life” – building blocks of artefacts Nature uses DNA to preserve information for organisms Nature uses DNA to preserve information for organisms Humans tend to throw away this same information and/or do not update it with advances Humans tend to throw away this same information and/or do not update it with advances Operations manual covered by countless layers of dust Operations manual covered by countless layers of dust Keeping information helps create products more efficiently and with better results Keeping information helps create products more efficiently and with better results Lets us see what worked/did not work before Lets us see what worked/did not work before Nature is inherently sustainable, so then a design process based off nature should also be sustainable Nature is inherently sustainable, so then a design process based off nature should also be sustainable

Analogous Processes Designed products and biological entities share many common phenomena Designed products and biological entities share many common phenomena Lifecycle processes, evolution, natural selection, mutation, etc Lifecycle processes, evolution, natural selection, mutation, etc

Evolution – why laptops are like giraffes Both evolved for specific reasons Both evolved for specific reasons Giraffe evolved a long neck to have no competition to eat the food from high branches Giraffe evolved a long neck to have no competition to eat the food from high branches The “toughbook” laptop evolved into a product which is more rugged to protect against accidental drops The “toughbook” laptop evolved into a product which is more rugged to protect against accidental drops

Products Evolving Products evolve over time Products evolve over time Evolve through external influences Evolve through external influences Internally, through genetic mutation or inter-breeding Internally, through genetic mutation or inter-breeding Through scientific advances Through scientific advances Light pen on hard specialized monitor Touch sensitive kiosk screen PDA with touch screen Mobile phone with touch screen

Natural Selection We use “natural selection” for artifacts We use “natural selection” for artifacts I term it ‘anthropogenic’ selection I term it ‘anthropogenic’ selection Consider “Beta” and “HD DVD” Consider “Beta” and “HD DVD” Selection is partly in/out of our control Selection is partly in/out of our control Factors like: Factors like: Environment Environment Media Media Market analysis Market analysis Economy Economy Current affairs Current affairs

Mutation Permanent change to the genetic structure Permanent change to the genetic structure Spontaneous or induced, beneficial or harmful Spontaneous or induced, beneficial or harmful Occurs in artefacts too Occurs in artefacts too Manufacturing defects Manufacturing defects On-site changes On-site changes Part replacement Part replacement Technology change Technology change Design decision Design decision

Analogous Structures Living things have a DNA profile, containing genes that describe the functional (and sometimes physical) characteristics. Living things have a DNA profile, containing genes that describe the functional (and sometimes physical) characteristics. Similarly, when we design a product, we start by creating a list of characteristics/functions we wish the final product to have. Similarly, when we design a product, we start by creating a list of characteristics/functions we wish the final product to have. Designs can be described by a DNA profile, made up of a set of genes, which describes the form Designs can be described by a DNA profile, made up of a set of genes, which describes the form Sometimes referred to as embodiments Sometimes referred to as embodiments A gene is expressed as a certain performance characteristic, feature or function A gene is expressed as a certain performance characteristic, feature or function Each gene then has a subset of 'gene options', which are possible outcomes of that gene Each gene then has a subset of 'gene options', which are possible outcomes of that gene

DbD Process Phase 1: DNA sequencing for a product line Phase 1: DNA sequencing for a product line Phase 2: Using the genome to design a new product in that line Phase 2: Using the genome to design a new product in that line

Product DNA Sequencing Must find the genetic structure for a product before we can use it Must find the genetic structure for a product before we can use it use DNA sequencing/gene mapping use DNA sequencing/gene mapping analysis of existing artifacts of a specified type and creation of the “genome” of that artifact type analysis of existing artifacts of a specified type and creation of the “genome” of that artifact type Ideally, we’d want to map out the genome for every product Ideally, we’d want to map out the genome for every product IE: pen, kettle, bicycle, etc IE: pen, kettle, bicycle, etc

A First Step Towards DNA Analyze a sample group of some existing product, in order to break it down into its DNA analogous components (genes) Analyze a sample group of some existing product, in order to break it down into its DNA analogous components (genes) Effectively; data mining Effectively; data mining Stats, product history, marketing, media, etc Stats, product history, marketing, media, etc Must take into account that the genes are context dependent Must take into account that the genes are context dependent ie: genes for the structure of a house will not be the same in different regions (Nunavut vs. Florida) ie: genes for the structure of a house will not be the same in different regions (Nunavut vs. Florida) Mobile phone charger Mobile phone charger

Creating Genes Once the characteristic genes for an artefact are identified and classified, they have to be made into usable forms Once the characteristic genes for an artefact are identified and classified, they have to be made into usable forms Each gene will be expressed through use of a pattern Each gene will be expressed through use of a pattern a pattern describes a process, method, or activities related to creating the artefact which they describe a pattern describes a process, method, or activities related to creating the artefact which they describe Each gene has genetic options Each gene has genetic options Gene for exterior cladding may have options for: brick, stucco, vinyl siding, etc Gene for exterior cladding may have options for: brick, stucco, vinyl siding, etc Each option contains performance characteristics Each option contains performance characteristics The stucco gene option has information on things like: lifetime, wear, thermal resistivity, air penetration rating, carbon footprint, etc The stucco gene option has information on things like: lifetime, wear, thermal resistivity, air penetration rating, carbon footprint, etc The gene pattern shows a designer how/when/where to use that gene/gene option The gene pattern shows a designer how/when/where to use that gene/gene option Gene patterns include a measure of sustainability Gene patterns include a measure of sustainability The patterns are linked via a pattern language The patterns are linked via a pattern language

An Artificial Genome A collection of gene patterns is analogous to a genome for an organism. A collection of gene patterns is analogous to a genome for an organism. One or more genes can define a chromosome One or more genes can define a chromosome One or more chromosomes defines a full genome One or more chromosomes defines a full genome This collection of artificial genetic information is the ‘artificial genome’. This collection of artificial genetic information is the ‘artificial genome’. The genome then contains enough information to reproduce an artefact, given certain contextual parameters The genome then contains enough information to reproduce an artefact, given certain contextual parameters Contextual parameters are usually in the customer requirements Contextual parameters are usually in the customer requirements These define what expectations and conditions an artefact must meet These define what expectations and conditions an artefact must meet Require the role of the designer Require the role of the designer

Using DNA to Create an Artefact

How do we use DbD? Similar or same opening steps as other methods Similar or same opening steps as other methods Problem analysis Problem analysis usage scenario usage scenario situation brainstorming situation brainstorming product requirements specification product requirements specification requirements validation/voice of the customer requirements validation/voice of the customer System architecture System architecture System/subsystem identification System/subsystem identification System diagram System diagram interface specs interface specs product architecture specs product architecture specs system validation system validation

How do we use DbD? – cont’d Concept design Concept design Ideation Ideation Generation Generation Evaluation Evaluation Selection Selection Refinement Refinement Product concept specification Product concept specification Concept validation Concept validation

Ideation - 1 For each chromosome (subsystem) in the genome (system), there exists a set of genes (sub-subsystems or parts) For each chromosome (subsystem) in the genome (system), there exists a set of genes (sub-subsystems or parts) For each gene, there exists a set of known and/or commonly found gene options (embodiments) For each gene, there exists a set of known and/or commonly found gene options (embodiments) As with biology, there could be options we haven’t discovered yet or that haven’t been applied to this product As with biology, there could be options we haven’t discovered yet or that haven’t been applied to this product We wish to pick the most suitable gene option for our given requirements and environment We wish to pick the most suitable gene option for our given requirements and environment

Ideation - 2 For each identified gene: For each identified gene: Observe the gene options Observe the gene options Assess how each option interacts and performs with the given requirements and contextual environment Assess how each option interacts and performs with the given requirements and contextual environment Given the above, choose the best option for that gene Given the above, choose the best option for that gene A rating scheme is useful to help make your choice A rating scheme is useful to help make your choice Rate options against the input variables (req’s/env.) Rate options against the input variables (req’s/env.) Repeat for all genes of the product Repeat for all genes of the product

Ideation - 3 Innovation and novelty can occur at this point Innovation and novelty can occur at this point Inter-breeding of gene options from similar genes in other products Inter-breeding of gene options from similar genes in other products Mutation of genes into new forms (changing a gene changes its functions/characteristics) Mutation of genes into new forms (changing a gene changes its functions/characteristics) Incandescent bulbs to CFL’s Incandescent bulbs to CFL’s Pen example Pen example What is the function of a pen? What is the function of a pen? To create a contrast on a given medium which is distinguishable to the human eye To create a contrast on a given medium which is distinguishable to the human eye Currently: mechanical movement of a nib Currently: mechanical movement of a nib Doesn’t a printer have the same function? And a monitor? Doesn’t a printer have the same function? And a monitor? Inter-breeding of pen with printer = new concept! Inter-breeding of pen with printer = new concept!

Ideation - 4 Given your choices of gene options: Given your choices of gene options: Assess how your gene choices within a chromosome interact with each other (refer to your PAS) Assess how your gene choices within a chromosome interact with each other (refer to your PAS) Interactions within chromosomes may affect your choices for genes Interactions within chromosomes may affect your choices for genes Re-evaluate your choices for genes given your assessment on the interactions Re-evaluate your choices for genes given your assessment on the interactions Sometimes, picking the optimal option within a gene does not work out within a chromosome Sometimes, picking the optimal option within a gene does not work out within a chromosome

Concept Generation - 1 Assemble the chromosomes together to create a full system concept Assemble the chromosomes together to create a full system concept Aka: combining ideas/embodiments to form concepts Aka: combining ideas/embodiments to form concepts Each new combination of your chromosomes is a new system concept Each new combination of your chromosomes is a new system concept It is possible that the exact same chromosomes may interact in different ways (given your PAS) to give rise to new concepts It is possible that the exact same chromosomes may interact in different ways (given your PAS) to give rise to new concepts Try some concepts that involve the inter-breeding or mutation from your ideation Try some concepts that involve the inter-breeding or mutation from your ideation

Evaluation - 1 Rank concepts to determine relative merits Rank concepts to determine relative merits Using something like a weighted decision matrix Using something like a weighted decision matrix

Evaluation - 2 Possible to encode evaluation criteria inside the genes Possible to encode evaluation criteria inside the genes Allows dynamic ideation evaluation Allows dynamic ideation evaluation Shows evaluation for every possible gene combination Shows evaluation for every possible gene combination Allows computer-aided ideation Allows computer-aided ideation Gives designers more time to innovate! Gives designers more time to innovate!

Refinement - 1 Given evaluations, refine some concepts Given evaluations, refine some concepts Similar or the same as other methods Similar or the same as other methods Add entirely new concepts Add entirely new concepts Take top performers and refine the weaker points Take top performers and refine the weaker points Take weak performers and consider the best points Take weak performers and consider the best points Combine 2 or more concepts to create a better one Combine 2 or more concepts to create a better one Discard poor designs Discard poor designs Re-evaluate remaining concepts Re-evaluate remaining concepts May take more than 1 iteration of refinement May take more than 1 iteration of refinement

Concept Winner After x iterations of refinement, pick a clear winner After x iterations of refinement, pick a clear winner Validate the winning concept against your: Validate the winning concept against your: Product requirements Product requirements System architecture System architecture Usually requires presenting the design to the customer for approval Usually requires presenting the design to the customer for approval

Kettle Example Containment system Containment system Heating system Heating system Control system Control system On/off On/off Safety off Safety off

EXTRA: DNA DNA is the inherited genetic material within an organism. Each gene is then a segment of its DNA. The genes are the chemical units that initiate the processes of organism development and growth, that determine the organism's characteristics and the characteristics that are inherited in a successive generations, and also regulate most of the activities which take place throughout the organism's lifetime. Genes ultimately influence all aspects of an organism's structure and function. Each chromosome contains 1 or more genes that describe the functional (and sometimes physical) characteristics of the entity. DNA is the inherited genetic material within an organism. Each gene is then a segment of its DNA. The genes are the chemical units that initiate the processes of organism development and growth, that determine the organism's characteristics and the characteristics that are inherited in a successive generations, and also regulate most of the activities which take place throughout the organism's lifetime. Genes ultimately influence all aspects of an organism's structure and function. Each chromosome contains 1 or more genes that describe the functional (and sometimes physical) characteristics of the entity. Gene characteristics can be classified as one of two different types; namely, genotypes and phenotypes. A basic definition is as follows: genotype refers to the structural composition of specific genes, whereas phenotype refers to the outward appearance of an individual, which results from both the genotype and the influence of the environment. A genotype does not result in a phenotype unless the genotype is expressed. Gene expression refers to the biochemical processes that result in an observable physical, structural, or behavioural effect in the individual. A dormant (non-expressed) gene has no impact on the individual, and its genotype can only be established via DNA profiling. Dormant genotypes can be activated by environmental effects. For example, some humans have a genetic predisposition to developing cancer; this means they have a genotype that is common to victims of cancer, but the genotype will only be triggered if subjected to some external effect – such as smoking cigarettes. Therefore, the 'form' of the DNA remains constant, though the expression of it may change from one manifestation to the next or through some trigger event. Gene characteristics can be classified as one of two different types; namely, genotypes and phenotypes. A basic definition is as follows: genotype refers to the structural composition of specific genes, whereas phenotype refers to the outward appearance of an individual, which results from both the genotype and the influence of the environment. A genotype does not result in a phenotype unless the genotype is expressed. Gene expression refers to the biochemical processes that result in an observable physical, structural, or behavioural effect in the individual. A dormant (non-expressed) gene has no impact on the individual, and its genotype can only be established via DNA profiling. Dormant genotypes can be activated by environmental effects. For example, some humans have a genetic predisposition to developing cancer; this means they have a genotype that is common to victims of cancer, but the genotype will only be triggered if subjected to some external effect – such as smoking cigarettes. Therefore, the 'form' of the DNA remains constant, though the expression of it may change from one manifestation to the next or through some trigger event.

EXTRA: Processes Evolution: Given a population of organisms, evolution proceeds based on two oppositional processes: mutation and interbreeding, which increases genetic diversity; and natural selection, which decreases genetic diversity. Mutation and interbreeding cause new variations in genes, which render as new physical characteristics (example: a longer neck). These characteristics manifest as new behaviours of organisms in successive generations to react to their environment (example: an ability to eat leaves from high tree branches). Natural selection is the impact that those behaviours have on the ability of the organisms to reproduce; this is usually interpreted as organisms living long enough to reproduce, but can also include time for offspring to mature, quantity of offspring per reproductive cycle, and other characteristics. If a given genetic change induces a characteristic that leads to a behaviour in a given environment that allows an organism to survive and/or reproduce better/faster, then over time that genetic change will become dominant in the overall population. For example, the long necks of giraffes lets them eat leaves of tall trees, that are inaccessible to other, short-necked herbivores, thus increasing the giraffe’s ability to access food compared to other animals. Natural Selection: Natural selection, as first coined by Charles Darwin, is a process by which characteristics that increase the likelihood of an organism's survival and successful reproduction in an environment become more commonplace within a population over successive generations. As an example, an increase in humankind's cognitive ability has allowed us to thrive as a species and thus natural selection over many generations of humans has seen an increase in our overall cognitive capacity, as compared to much earlier generations. A more straightforward example is the giraffe's neck, which evolved to give the giraffe the ability to reach vegetation no other footed animal could reach, thereby increasing its ability to survive. Evolution: Given a population of organisms, evolution proceeds based on two oppositional processes: mutation and interbreeding, which increases genetic diversity; and natural selection, which decreases genetic diversity. Mutation and interbreeding cause new variations in genes, which render as new physical characteristics (example: a longer neck). These characteristics manifest as new behaviours of organisms in successive generations to react to their environment (example: an ability to eat leaves from high tree branches). Natural selection is the impact that those behaviours have on the ability of the organisms to reproduce; this is usually interpreted as organisms living long enough to reproduce, but can also include time for offspring to mature, quantity of offspring per reproductive cycle, and other characteristics. If a given genetic change induces a characteristic that leads to a behaviour in a given environment that allows an organism to survive and/or reproduce better/faster, then over time that genetic change will become dominant in the overall population. For example, the long necks of giraffes lets them eat leaves of tall trees, that are inaccessible to other, short-necked herbivores, thus increasing the giraffe’s ability to access food compared to other animals. Natural Selection: Natural selection, as first coined by Charles Darwin, is a process by which characteristics that increase the likelihood of an organism's survival and successful reproduction in an environment become more commonplace within a population over successive generations. As an example, an increase in humankind's cognitive ability has allowed us to thrive as a species and thus natural selection over many generations of humans has seen an increase in our overall cognitive capacity, as compared to much earlier generations. A more straightforward example is the giraffe's neck, which evolved to give the giraffe the ability to reach vegetation no other footed animal could reach, thereby increasing its ability to survive. Mutation: A mutation is a permanent change to the underlying genetic structure of an organism. Mutations can be beneficial or harmful, depending on whether it affects the organism's survival (per natural selection) positively or negatively. Mutations can be spontaneous or induced. A spontaneous mutation occurs as the result of a variation in the chemical processes of genetics, such as molecular decay occurring spontaneously during the life of an individual?. An induced mutation occurs in response to an external stimulus or phenomenon, such as exposure to nuclear radiation, prolonged change in nutritional intake, or an intended alteration by a designer. Mutation: A mutation is a permanent change to the underlying genetic structure of an organism. Mutations can be beneficial or harmful, depending on whether it affects the organism's survival (per natural selection) positively or negatively. Mutations can be spontaneous or induced. A spontaneous mutation occurs as the result of a variation in the chemical processes of genetics, such as molecular decay occurring spontaneously during the life of an individual?. An induced mutation occurs in response to an external stimulus or phenomenon, such as exposure to nuclear radiation, prolonged change in nutritional intake, or an intended alteration by a designer.