Workflow Diagram for the Natural Product/Metabolite/Discovery Chemist LC vacuum centrifuge MS DAD/ELSD or bioactivity NMR Purification Fraction Collection.

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Presentation transcript:

Workflow Diagram for the Natural Product/Metabolite/Discovery Chemist LC vacuum centrifuge MS DAD/ELSD or bioactivity NMR Purification Fraction Collection or Purified Samples Prep Stage Report Crude Samples/Mixtures Low Sensitivity Detection High Sensitivity Detection 1

Modern Sample Formats: The Wellplate and the Microvial No shimming between samples No washing tubes Minimal sample transfer Efficient storage Disposable Economical Incredible Time Savings Plates Make It Easy 2

Protasis One Minute NMR Automation Sample Return Stacked Sample Drawers Wash Bays Microliter Precision Near Zero Dead Volume Easy Parameter Setup Solvent Conditioning Wellplate Web-based Software 3

Solvent Microfilter Vial Spatula MicrofilterSample Step 1: Add sample (5 – 500  g) Step 2: Add solvent (5 – 15  L) Step 3: Spin down (~ 1 min.) Step 4: Discard microfilter Step 5: Place vial on OMNMR Quality Results Start with a Quality Sample 4

Preparative Filtration, Sample Concentrator Microfilter Vial Protasis P/N: PREP-OAFST-FV Unique Protasis product Ensures particulate-free, high-quality sample Benchtop “Point of Use” Centrifuge Ideal for open-access 500 Microfiltration Vials Easy to use! Discrete Sample Microfiltration Vacuum Centrifugation Protasis P/N: PREP-OAFST-VC Protonated-to-deuterated solvent Sample concentrator Variety of vendor options Customer may opt to purchase separately Summary: Open-access, discrete sample filtration?  PREP-OAFST-FV Solvent removal, deuterated solvent replacement?  PREP-OAFST-VC