Ebola Virus Disease Clinical manifestations Ebola Virus Disease Clinical manifestations N. Shindo Lead, Clinical & Infection Control Pandemic & Epidemic.

Slides:



Advertisements
Similar presentations
Viral Haemorrhagic Fever: The West African Zaire Ebola Virus outbreak
Advertisements

(EVD) By Dr Lekan Adelakun Impact Healthserve Ltd Quaint Consultants (Advocacy For Health And Safety Programmes) Tel: , quaint consultants.
* Ebola virus disease (EVD), formerly known as Ebola hemorrhagic fever, is a severe, often fatal illness in humans. * EBOLA is a rare but deadly virus.
What is Ebola? 10/12/2014. What is Ebola? Filoviridae Ebolavirus – 5 viruses/species – Ebola (Zaire) – Sudan – Bundibugyo – Tai Forest – Reston Marburgvirus.
E bola Dr Nick Gent. current situation On 23 March 2014, WHO confirmed an outbreak of Ebola virus disease (EVD) in South-eastern Guinea, the first time.
Any of the following risk factors within 3 weeks (21 days) before onset of symptoms 1,2 : Contact with blood or other body fluids of a patient known to.
Any of the following risk factors within 3 weeks (21 days) before onset of symptoms 1,2 : Contact with blood or other body fluids of a patient known to.
EVD is a preventable but often fatal viral infection An EVD outbreak is affecting countries in West Africa where disease control resources are very limited.
Transmission The virus is transmitted to people from wild animals and spreads in the human population through human-to-human transmission. Human-to-human.
What is Ebola? Ebola is a rare and deadly disease caused by infection with the Ebola virus. It is only spread by direct contact with an infected person's.
Ebola – Facts, Myths, and Fiction Dr M. Oladoyin Odubanjo Executive Secretary, The Nigerian Academy of Science (NAS) 1st Vice Chair, Association of Public.
Ebola Virus Disease. EVD Description Hemorrhagic fever with case fatality rate up to 90% Endemic areas: Central and West Africa Wildlife reservoir: bats.
Ebola Virus. What is Ebola hemorrhagic fever? Ebola hemorrhagic fever (Ebola HF) is a severe, often-fatal disease in humans and nonhuman primates (monkeys,
EBOLA OUTBREAK 2014 There has never been an outbreak this size and severity.
PRSENTATION ABOUT EBOLA BY -PARTH MONGA INFORMATION IS BASED UPON VARIOUS RESERCH MATERIALS, I HAVE ONLY COMPOSED IT.FOR THE PURPOSE OF CREATING AWARENESS-PARTH.
The current outbreak of Ebola in west Africa is both a public health emergency of international concern and a human tragedy.
Ebola Facts October 14, Symptoms of Ebola Initial symptoms are nonspecific - may include fever, chills, myalgias, and malaise. Patients can progress.
Ebola Virus "Ebola hemorrhagic fever" Created by: Lexington Pittman Michael Trent Jake.
Washington State Ebola Response: From Identify, Isolate and Inform to Frontline, Assessment and Treatment Scott Lindquist MD MPH State Communicable Disease.
2014 Ebola Virus Outbreak. What is a Virus? Viruses are microscopic particles (10 – 400 nm). Viruses are made of genetic material (DNA or RNA) surrounded.
INTEGRIS Preparedness Plan: Ebola Virus Disease (EVD) With the spread of Ebola to the U.S., ensuring our employees and communities are safe is the utmost.
Ebola Virus Disease (EVD) Updated 11:30 a.m
Division of Public Health Services New Hampshire Department of Health and Human Services Eastern Equine Encephalitis (EEE) in New Hampshire Dianne Donovan,
EBOLA Virus Disease August 22, What is Ebola Virus Disease (EVD)? Ebola virus disease (also known as Ebola hemorrhagic fever) is a severe, often-fatal.
Ebola Virus Disease, West Africa outbreak 2014 An update on cases 21/04/2015 To update slides with most recent figures, please follow links and instructions.
Ebola Facts October 14, Symptoms of Ebola Initial symptoms are nonspecific - may include fever, chills, myalgias, and malaise. Patients can progress.
A deadly Disease  Solon, the sage of Athens, argued that one couldn't judge a person's happiness until one knew the manner of his death.  The Greeks.
Network modeling of the Ebola Outbreak Ahmet Aksoy.
Ebola Virus Disease Dr. Oluwafemi Akinyele Popoola Lecturer and Consultant Community Physician Lecture delivered at Bodija-Ashi Baptist Church 14 th September,
Ebola Virus Outbreak This presentation has been prepared by Christine H. Herrmann, Ph.D. of the Department of Molecular Virology and Microbiology at Baylor.
Ebola virus  The Ebola virus causes an acute, serious illness which is often fatal if untreated.  The most severely affected countries are: Guinea,
Ebola virus disease. Key facts Ebola virus disease (EVD), formerly known as Ebola haemorrhagic fever, is a severe, often fatal illness in humans. The.
EBOLA Kyle Draves. Pathogen Zaire Ebola Virus  Also known as EBOV  One of five viruses of the genus Ebolavirus  EBOV is most virulent of the five;
EBOLA - ZAIRE. PPE – Personal Protection Equiptment.
EBOLA VIRUS FREQUENTLY ASKED QUESTIONS. What is Ebola virus disease? (Formerly Ebola haemorrhagic fever)- a severe, often fatal illness, with a DEATH.
Why persistence of Ebola community deaths in Conakry, Guinea? Conakry, January 1st – February 12th 2015 Dominique Jeannel 1,2, Laurel Delayo-Zomahoun 1,
 An acute, severe viral infection  First appeared in 1976 in two simultaneous outbreaks  in a village near the Ebola River in the Democratic Republic.
EBOLA HAEMORRHAGIC FEVER – BLEEDING FEVER 7NEWS EBOLA UPDATE.
As per CDC and WHO, Recent outbreak of Ebola Virus Disease(EVD), New cases and deaths attributable to EVD continue to be reported by the Ministries of.
Patrice Gordon, Family Nurse Practitioner Canadian Red Cross Emergency Response Unit Kenema Ebola Treatment Centre, Sierra Leone 1.
Marburg and Lassa viruses ศาสตราจารย์ ดร. พิไลพันธ์ พุธ วัฒนะ ศูนย์ความร่วมมือการวิจัยไข้หวัดใหญ่ ภาควิชาจุลชีววิทยา คณะแพทยศาสตร์ศิริราช พยาบาล มหาวิทยาลัยมหิดล.
Training on the Ebola Virus Disease (duration 3 days)
THE EBOLA CRISIS What is Ebola? Ebola virus disease (EVD) or Ebola Hemorrhagic Fever (EHF) is a disease of humans and other primates caused by the Ebola.
EBOLA VIRUS DISEASE PREPAREDNESS Screening, Detection & Planning.
Outbreaks and Epidemics Ebola Hemorrhagic Fever. Ebola facts and origins  Ebola hemorrhagic fever is a severe, often-fatal disease in humans and nonhuman.
The Ebola Outbreak of What is Ebola? It’s a virus It causes EBV (Ebola virus disease) which is a hemorrhagic fever. It affects many organs and blood.
Risk factors for severe disease from pandemic (H1N1) 2009 virus infection reported to date are considered similar to those risk factors identified for.
Updates on Ebola Virus Disease (EVD) Divina Cabral-Antonio Regional Epidemiology and Surveillance Unit.
Ebola virus disease (EVD), formerly known as Ebola haemorrhagic fever, is a severe, often fatal illness in humans. The virus is transmitted to people.
Lutte contre l’infection : leçons à retenir dans le contexte de l’épidémie Ebola 26 Novembre eme Journée Romande d’Hygiène Hospitalière Dr Constanza.
Ebola Virus Disease: Occupational Safety and Health.
Quick Insights on Some Viral Issues Dr. Haya Al-Tawalah Clinical Virologist.
Information on the Ebola surge in West Africa All you need to know about Ebola (HF) -Jazlyn Selvasingh.
By Angus. Some of the symptoms are headache, Red eyes, Fever, lack of appetite, internal bleeding, muscle aches and weakness, aching joints Diarrhea,
Patient with Ebola Hemorrhagic Fever, Bumba Zone, Equateur Province, DR Congo (Zaire), October 1976.
DR I.O.LAWAL MBChB(Ife),FWACS(Urol). EBOLA VIRUS DISEASE Introduction Epidemiology Transmission Signs & Symptoms Diagnosis Differentials Treatment/ Health.
Ebola Facts October 14, 2014.
Ebola Virus and development
VIRAL HAEMORRHAGIC FEVERS
BY DR. MUDAMA PRECIOUS (M.B.B.S., BENIN)
Ebola Facts October 14, 2014.
Ebola Virus Disease (EVD) WHAT IS IT?
Ebola Facts October 14, 2014.
EBOLA VIRUSES (SYMPTOMS, TREATMENT AND CAUSES) Nama : Siti Sofea Annisa Binti Sheikh Mohamad No. Matric : Lecturer : Madam Siti Wahida Binti.
EBOLA VIRUS DISEASE Joseph P. Iser, MD, DrPH, MSc Southern Nevada Health District.
Active Surveillance for EHF Cases, Equateur Province, DR Congo (Zaire), November-December 1976
DEPARTMENT OF MEDICINE, UOM
Ebola Facts October 14, 2014.
Ebola Facts October 14, 2014.
Presentation transcript:

Ebola Virus Disease Clinical manifestations Ebola Virus Disease Clinical manifestations N. Shindo Lead, Clinical & Infection Control Pandemic & Epidemic Diseases Department

2 |2 | Ebola virus disease outbreak in 2014 Caused by Zaire ebolavirus WHO clinicians have been working in all three countries with national and international partners Data are based on two journal publications to which WHO clinical network contributed: –Clinical presentation of patients with Ebola Virus Disease in Conakry, Guinea. NEJM, 2014 –Clinical illness and outcomes in patients with Ebola in Sierra Leone. NEJM, 2014

3 |3 | Common features Guinea case series (N=37) Sierra Leone Case series (N=44)* Fever31/37 (84%)89% Fatigue24/27 (65%) 66% (weakness) Headache12/21 (57%)80% Diarrhoea23/37 (62%)51% Vomiting21/36 (57%)34% * At the time of presentation

4 |4 | Other symptoms Abdominal pain 40% (SL) Sore throat 34% (SL) Conjunctivitis 31% (SL) Tachycardia 62% (Guinea) Hiccups 28% (Guinea) Skin rush ( patients in Europe and USA)

5 |5 | Fatigue or weakness, Fever, headache, sore throat Non-specific, differential diagnosis difficult –Malaria –Influenza-like Illness –Lassa fever –Typhoid fever Initial symptoms of EVD

6 |6 | EVD Disease clinical course (fatal patients) Prodrome? Onset GI symptoms Shock, multiorgan failure Hemorragic symptoms death Incubation period (2-21 days) SL: 6-12 days Case fatality rate: 74% (SL), 43% (Guinea) 4-5 days 8 (7-11) days (SL) 4-5 days

7 |7 | Other points Older age group more likely to have severe outcomes including death (40 years or older, 3.5 times more, Guinea) Severe dehydration, hypovolemic shock and electrolytes/metabolic abnormalities lead to multiorgan failure and death Some CNS symptoms: confusion, delirium, convulsions Case fatality rate differs from one place to the other Ebola haemorrhagic fever vs Ebola virus disease –Seen in about a half of fatal patients (Guinea) –Late complication in severe illness

8 |8 | Challenges Frontline healthcare workers are at risk of being exposed to dangerous pathogens and also can become sources of healthcare associated infection, Too busy and occupied to manage patients and no time or resource for data collection, Have limited information due to lack of resources for case management and treatment.

9 |9 | Needs for means to play the role Efficient case detection – Triage System in place for reporting Good & safe biological sample collection for laboratory testing – Sampling (Which? How?) and better access with capable laboratories Better treatment – syndromic approach, evidence based  Motivation Protect self, colleagues, patients and environment

10 | Clinical network activities Deployment of ID physician and Intensive/critical care specialists to support clinicians at EVD treatment centres VHF case management 'Pocket Book' based on IMAI approach both in English and French

11 | Ebola Virus Disease Outbreak in West Africa 2014 LET'S UNITE AND HELP JOIN US!!!